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Journal of Controlled Release, ISSN 0168-3659, 06/2019, Volume 303, pp. 91 - 100
Retinal gene therapy has had unprecedented success in generating treatments that can halt vision loss. However, immunogenic response and long-term toxicity... 
Eye | Retinal degeneration | Retina | mRNA | Transfection efficiency | Lipid nanoparticle | CELLS | EFFICACY | OPEN-LABEL | SIRNA DELIVERY | CHEMISTRY, MULTIDISCIPLINARY | CHALLENGES | CATIONIC LIPIDS | IMMUNOGENICITY | DNA NANOPARTICLES | INTRACELLULAR DELIVERY | PHARMACOLOGY & PHARMACY | EFFICIENT | Nanoparticles | Anopheles | Messenger RNA | Genes | Genomics | World health | Lipids | Gene therapy | Gene expression
Journal Article
Retina, ISSN 0275-004X, 04/2019, p. 1
PURPOSEChoroideremia is an incurable, X-linked, recessive retinal dystrophy caused by loss of function mutations in the CHM gene. It is estimated to affect... 
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 01/2018, Volume 59, Issue 1, pp. 462 - 471
PURPOSE. To characterize the mediators of 5-HT2A serotonin receptor-driven retinal neuroprotection. METHODS. Albino mice were treated intraperitoneally with... 
Retinal degeneration | Light damage | MAPK/ERK | Sarpogrelate | 5-HT2A | PATHWAYS | APOPTOSIS | retinal degeneration | ANTAGONIST | PROTECTION | PHOSPHORYLATION | G-PROTEINS | MAP KINASES | MECHANISMS | light damage | DEGENERATION | PHOTORECEPTOR CELL-DEATH | sarpogrelate | OPHTHALMOLOGY | Index Medicus | Retina | MAPK | ERK
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2015, Volume 112, Issue 18, pp. E2395 - E2402
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 06/2016, Volume 134, Issue 6, p. 697
  Novel therapies for choroideremia, an X-linked recessive chorioretinal degeneration, demand a better understanding of the primary site(s) of cellular... 
Macular degeneration | Medical imaging | Blindness | Tomography | Pigments
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 06/2015, Volume 133, Issue 6, p. 653
  The patients evaluated in this study, to our knowledge, represent the first complete clinical description of a family with an autosomal dominant inheritance... 
Genotype & phenotype | Genetics | Mutation | Patients
Journal Article
ISSN 1932-6203, 2016
Purpose: To assess the neuroprotective effects of flibanserin (formerly BIMT-17), a dual 5-HT1A agonist and 5-HT2A antagonist, in a light-induced retinopathy... 
Medicine | Neurosciences | Serotonin--Receptors | Retina | Neuroprotective agents | Psychiatry | Apoptosis
Journal Article
Journal Article
Vision Research, ISSN 0042-6989, 12/2015, Volume 117, p. 136
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 2015, Volume 56, Issue 8, pp. 4560 - 4569
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 07/2014, Volume 132, Issue 7, pp. 823 - 823
  While older children and adults with achromatopsia have been studied, less is known of young children with achromatopsia. To characterize the macular and... 
Genotype & phenotype | Correlation analysis | Morphology | Retina | Mutation | Genetic testing | Children & youth
Journal Article
Vision Research, ISSN 0042-6989, 12/2015, Volume 117, pp. 136 - 136
Journal Article
Retina Today, 2015, Issue 2015, pp. 53 - 56
Journal Article
Translational vision science & technology, ISSN 2164-2591, 05/2019, Volume 8, Issue 3, p. 17
We determine the intersession repeatability of cone measurements via flood-illuminated adaptive optics (AO) imaging in patients with retinitis pigmentosa (RP),... 
Journal Article
Journal Article
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