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1. Full Text Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression
by Culverhouse, R C and Saccone, N L and Horton, A C and Ma, Y and Anstey, K J and Banaschewski, T and Burmeister, M and Cohen-Woods, S and Etain, B and Fisher, H L and Goldman, N and Guillaume, S and Horwood, J and Juhasz, G and Lester, K J and Mandelli, L and Middeldorp, C M and Olié, E and Villafuerte, S and Air, T M and Araya, R and Bowes, L and Burns, R and Byrne, E M and Coffey, C and Coventry, W L and Gawronski, K A B and Glei, D and Hatzimanolis, A and Hottenga, J-J and Jaussent, I and Jawahar, C and Jennen-Steinmetz, C and Kramer, J R and Lajnef, M and Little, K and Zu Schwabedissen, H M and Nauck, M and Nederhof, E and Petschner, P and Peyrot, W J and Schwahn, C and Sinnamon, G and Stacey, D and Tian, Y and Toben, C and Van der Auwera, S and Wainwright, N and Wang, J-C and Willemsen, G and Anderson, I M and Arolt, V and Åslund, C and Bagdy, G and Baune, B T and Bellivier, F and Boomsma, D I and Courtet, P and Dannlowski, U and de Geus, E J C and Deakin, J F W and Easteal, S and Eley, T and Fergusson, D M and Goate, A M and Gonda, X and Grabe, H J and Holzman, C and Johnson, E O and Kennedy, M and Laucht, M and Martin, N G and Munafò, M R and Nilsson, K W and Oldehinkel, A J and Olsson, C A and Ormel, J and Otte, C and Patton, G C and Penninx, B W J H and Ritchie, K and Sarchiapone, M and Scheid, J M and Serretti, A and Smit, J H and Stefanis, N C and Surtees, P G and Völzke, H and Weinstein, M and Whooley, M and Nurnberger, J I and Breslau, N and Bierut, L J
Molecular psychiatry, ISSN 1359-4184, 2018, Volume 23, Issue 1, pp. 133 - 142
SAMPLE | COHORT PROFILE | CHILDHOOD MALTREATMENT | ENVIRONMENT INTERACTION | POLYMORPHISM 5-HTTLPR | DISORDER | RISK | MAJOR DEPRESSION | SEROTONIN TRANSPORTER GENE | LIFE EVENTS | Journal Article | Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Stress, Psychological - genetics | Genetic Predisposition to Disease | Serotonin Plasma Membrane Transport Proteins - genetics | Humans | Life Change Events | Cooperative Behavior | Depression - psychology | Genotype | Depression - genetics | Gene-Environment Interaction | Stress, Psychological - complications | Genetic aspects | Research | Depression, Mental | Risk factors | Data analysis | Statistical analysis | Serotonin | Data processing | Mental depression | Subgroups | Strong interactions (field theory) | Consortia | Genotype & phenotype | Hypotheses | Serotonin transporter | Alleles | Children | Transporter | Genotypes | Index Medicus | Life Sciences
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2. Full Text The impact of low-frequency and rare variants on lipid levels
by Surakka, Ida and Horikoshi, Momoko and Mägi, Reedik and Sarin, A.-P and Mahajan, Anubha and Lagou, Vasiliki and Marullo, Letizia and Ferreira, Teresa and Miraglio, Benjamin and Timonen, Sanna and Kettunen, Johannes and Pirinen, Matti and Karjalainen, Juha and Thorleifsson, Gudmar and Hägg, Sara and Hottenga, Jouke Jan and Isaacs, Aaron and Ladenvall, Claes and Beekman, Marian and Esko, Tõnu and Ried, Janina and Nelson, Christopher P and Willenborg, Christina and Gustafsson, Stefan and Westra, Harm-Jan and Blades, Matthew and De Craen, Anton J. M and Geus, Eco and Deelen, Joris and Grallert, Harald and Hamsten, Anders and Havulinna, Aki and Hengstenberg, Christian and Houwing-Duistermaat, Jeanine and Hypponen, Elina and Karssen, Lennart and Lehtimäki, Terho and Lyssenko, Valeriya and Magnusson, Patrik and Mihailov, Evelin and Müller-Nurasyid, Martina and Mpindi, John-Patrick and Pedersen, Nancy L and Penninx, Brenda and Perola, Markus and Pers, Tune and Peters, Annette and Rung, Johan and Smit, Johannes and Steinthorsdottir, Valgerdur and Tobin, Martin and Tsernikova, Natalia and Leeuwen, Elisa and Viikari, Jorma and Willems, Sara and Willemsen, Gonneke and Schunkert, Heribert and Erdmann, Jeanette and Samani, Nilesh and Kaprio, Jaakko and Lind, Lars and Gieger, Christian and Metspalu, Anes and Slagboom, Eline and Groop, Leif and Duijn, Cornelia and Eriksson, Johan G and Jula, Antti and Salomaa, Veikko and Boomsma, Dorret and Power, Christopher and Raitakari, Olli T and Ingelsson, Erik and Jarvelin, Marjo-Riitta and Thorsteinsdottir, Unnur and Franke, Lude and Ikonen, Elina and Kallioniemi, Olli and Pietiäinen, Vilja and Lindgren, Cecilia M and Zwart, John-Anker and Palotie, Aarno and McCarthy, Mark and Morris, Anew and Prokopenko, Inga and Ripatti, Samuli and ENGAGE Consortium
Nature genetics, ISSN 1061-4036, 01/2015, Volume 47, Issue 6, pp. 589 - 597
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Dyslipidemias - genetics | Genome-Wide Association Study | Gene Frequency | Humans | Lipid Metabolism - genetics | Polymorphism, Single Nucleotide | Genetic Loci | Mutation, Missense | Sequence Analysis, DNA | Linkage Disequilibrium | Genetic aspects | Single nucleotide polymorphisms | Lipid metabolism | Identification and classification | Health aspects | Studies | Design | Lipids | Agreements | Cholesterol | Index Medicus | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
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3. Full Text Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group
by Schmaal, L and Hibar, D.P and Sämann, Philipp and Hall, Garry and Baune, B.T and Jahanshad, Neda and Cheung, J.W and Erp, Theo G and Bos, Daniel and Ikram, Kamran and Vernooij, Meike and Niessen, Wiro and Tiemeier, Henning and Hofman, Albert and Wittfeld, Katharina and Grabe, Hans Jörgen and Janowitz, Deborah and Bülow, R and Selonke, M and Völzke, Henry and Grotegerd, D and Dannlowski, U and Arolt, Volker and Opel, N and Heindel, W and Kugel, H and Hoehn, David and Czisch, Michael and Couvy-Duchesne, Baptiste and Rentería, Miguel and Strike, Lachlan and Wright, Margaret and Mills, N.T and Zubicaray, Greig and Mcmahon, Katie and Medland, Sarah and Martin, Nicholas and Gillespie, N.A and Goya-Maldonado, R and Gruber, Oliver and Krämer, Bernhard and Hatton, W and Lagopoulos, Jim and Hickie, Ian and Frodl, Thomas and Carballedo, A and Frey, E.M and Van Velzen, L.S and Penninx, Brenda and Tol, Marie-José and Wee, Nic and Davey, Christopher and Harrison, B.J and Mwangi, Benson and Cao, B and Soares, J.C and Veer, Ilya and Walter, Henrik and Schoepf, D and Zurowski, B and Konrad, C and Schramm, E and Normann, C and Schnell, Kerry and Sacchet, M.D and Gotlib, I.H and MacQueen, Glenda and Godlewska, Beata and Nickson, T and McIntosh, Anew and Papmeyer, Martina and Whalley, H.C and Hall, Jeremy and Sussmann, Jessika and Li, M and Walter, M and Aftanas, L and Brack, I and Bokhan, N.A and Thompson, Paul and Veltman, Dick and ENIGMA Major Depressive and for the ENIGMA-Major Depressive Disorder Working Group
Molecular psychiatry, ISSN 1359-4184, 06/2017, Volume 22, Issue 6, pp. 900 - 909
Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Physiological aspects | Cerebral cortex | Diagnosis | Abnormalities | Major depressive disorder | Index Medicus | Original
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4. Full Text Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
by Aulchenko, Yurii and Ripatti, Samuli and Lindqvist, Ida and Boomsma, Dorret and Heid, Iris and Pramstaller, Peter Paul and Penninx, Brenda and Janssens, Cécile and Wilson, James and Spector, Timothy and Martin, Nicholas and Pedersen, Nancy and Kyvik, Kirsten Ohm and Kaprio, Jaakko and Hofman, Albert and Freimer, Nelson and Jarvelin, Marjo-Riitta and Gyllensten, Ulf and Campbell, Harry and Rudan, Igor and Johansson, Åsa and Marroni, Fabio and Hayward, Caroline and Vitart, Veronique and Jonasson, Inger and Pattaro, Cristian and Wright, Alan and Hastie, Nick and Pichler, Irene and Hicks, Anew and Falchi, Mario and Willemsen, Gonneke and Hottenga, Jouke Jan and Geus, Eco and Montgomery, Grant and Whitfield, John and Magnusson, Patrik and Saharinen, Juha and Perola, Markus and Silander, Kaisa and Isaacs, Aaron and Sijbrands, Eric and Uitterlinden, Ané and Witteman, Jacqueline and Oostra, Ben and Elliott, Paul and Ruokonen, Aimo and Sabatti, Chiara and Gieger, Christian and Meitinger, Thomas and Kronenberg, Florian and Döring, Angela and Wichmann, Erich and Smit, Johannes and McCarthy, Mark and Tikka-Kleemola, Päivi and Peltonen, Leena Johanna and Engage Consortium and ENGAGE Consortium and the ENGAGE Consortium
Nature genetics, ISSN 1061-4036, 01/2009, Volume 41, Issue 1, pp. 47 - 55
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Cardiology. Vascular system | Heart | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Coronary heart disease | Body Mass Index | Coronary Disease - blood | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genetic Testing | Humans | Middle Aged | Male | Sex Characteristics | Genome, Human - genetics | Metabolic Networks and Pathways - genetics | Phenotype | Coronary Disease - genetics | Lipids - blood | Adolescent | Aged, 80 and over | Cholesterol, HDL - blood | Polymorphism, Single Nucleotide - genetics | Adult | Female | Aged | Cohort Studies | Quantitative Trait Loci - genetics | Physiological aspects | Genetic aspects | Blood lipids | Research | Single nucleotide polymorphisms | Risk factors | Studies | Medical research | Environmental health | Data collection | Cardiovascular disease | Lipids | Population | Public private partnerships | Diabetes | Cholesterol | Family physicians | Index Medicus | Medicin och hälsovetenskap
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5. Full Text Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
by Wray, Naomi R and Ripke, Stephan and Mattheisen, Manuel and Trzaskowski, MacIej and Byrne, Enda M and Abdellaoui, Abdel and Adams, Mark J and Agerbo, Esben and Air, Tracy M and Andlauer, Till M. F and Bacanu, Silviu-Alin and Bækvad-Hansen, Marie and Beekman, Aartjan F. T and Bigdeli, Tim B and Binder, Elisabeth B and Blackwood, Douglas R. H and Bryois, Julien and Buttenschøn, Henriette N and Bybjerg-Grauholm, Jonas and Cai, Na and Castelao, Enrique and Christensen, Jane Hvarregaard and Clarke, Toni-Kim and Coleman, Jonathan I. R and Coloo-Conde, Lucía and Couvy-Duchesne, Baptiste and Craddock, Nick and Crawford, Gregory E and Crowley, Cheynna A and Dashti, Hassan S and Davies, Gail and Deary, Ian J and Degenhardt, Franziska and Derks, Eske M and DIrek, Nese and Dolan, Conor V and Dunn, Erin C and Eley, Thalia C and Eriksson, Nicholas and Escott-Price, Valentina and Kiadeh, Farnush Hassan Farhadi and Finucane, Hilary K and Forstner, Aneas J and Frank, Josef and Gaspar, H. léna A and Gill, Michael and Giusti-Roíguez, Paola and Goes, Fernando S and Gordon, Scott D and Grove, Jakob and Hall, Lynsey S and Hannon, Eilis and Hansen, Christine S. holm and Hansen, Thomas F and Herms, Stefan and Hickie, Ian B and Hoffmann, Per and Homuth, Georg and Horn, Carsten and Hottenga, Jouke-Jan and Hougaard, David M and Hu, Ming and Hyde, Craig L and Ising, Marcus and Jansen, Rick and Jin, Fulai and Jorgenson, Eric and Knowles, James A and Kohane, Isaac S and Kraft, Julia and Kretzschmar, Warren W and Krogh, Jesper and Kutalik, Zoltán and Lane, Jacqueline M and Li, Yihan and Li, Yun and Lind, Penelope A and Liu, Xiaoxiao and Lu, Leina and MacIntyre, Donald J and MacKinnon, Dean F and Maier, Robert M and Maier, Wolfgang and Marchini, Jonathan and Mbarek, Hamdi and McGrath, Patrick and McGuffin, Peter and Medland, Sarah E and Mehta, D. Ivya and Middeldorp, Christel M and Mihailov, Evelin and Milaneschi, Yuri and Milani, Lili and Mill, Jonathan and Mondimore, Francis M and Montgomery, Grant W and Mostafavi, Sara and Mullins, Niamh and Nauck, Matthias and Ng, Bernard and ... and Major Depressive Disorder Working and EQTLGEN and eQTLGen and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium and 23andMe and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Nature genetics, ISSN 1061-4036, 2018, Volume 50, Issue 5, pp. 668 - 681
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Phenotype | Schizophrenia - genetics | Depressive Disorder, Major - genetics | Humans | Risk Factors | Female | Male | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Multifactorial Inheritance | Case-Control Studies | Brain | Phenotypes | Splicing | Mental disorders | Genomics | Schizophrenia | Genomes | Mental depression | Risk analysis | Gene expression | Suicide | Morbidity | Risk factors | Educational attainment | Meta-analysis | Consortia | Liability | Body mass | Etiology | Education | Body size | DNA methylation | Gene loci | Deoxyribonucleic acid--DNA | Index Medicus | Medicin och hälsovetenskap
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6. Full Text Subcortical brain alterations in major depressive disorder: Findings from the ENIGMA Major Depressive Disorder working group
by Schmaal, Lianne and Veltman, Dick and Van Erp, T.G.M and Smann, P.G and Frodl, Thomas and Jahanshad, N and Loehrer, Elizabeth and Tiemeier, Henning and Hofman, A and Niessen, Wiro and Vernooij, Meike and Ikram, Arfan and Wittfeld, Katharina and Grabe, Hans Jörgen and Block, Anea and Hegenscheid, Katrin and Völzke, Henry and Hoehn, David and Czisch, Michael and Lagopoulos, Jim and Hatton, W and Hickie, Ian and Goya-Maldonado, R and Krmer, B and Gruber, O and Couvy-Duchesne, Baptiste and Rentera, M.E and Strike, Lachlan and Mills, N.T and Zubicaray, Greig and Mcmahon, Katie and Medland, Sarah and Martin, Nicholas and Gillespie, N.A and Wright, Margaret and Hall, G.B and MacQueen, Glenda and Frey, E.M and Carballedo, A and Van Velzen, L.S and Tol, Marie-José and Wee, Nic and Veer, Ilya and Walter, H and Schnell, K and Schramm, E and Normann, C and Schoepf, D and Konrad, C and Zurowski, B and Nickson, T and McIntosh, Anew and Papmeyer, Martina and Whalley, H.C and Sussmann, Jessika and Godlewska, Beata and Cowen, P.J and Fischer, F.H and Rose, M and Penninx, Brenda and Thompson, P.M and Hibar, Derrek and ENIGMA-Major Depressive Disorder W and for the ENIGMA-Major Depressive Disorder Working Group
Molecular psychiatry, ISSN 1359-4184, 06/2016, Volume 21, Issue 6, pp. 806 - 812
Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Neuroimaging - methods | Depressive Disorder, Major - pathology | Magnetic Resonance Imaging | Humans | Middle Aged | Brain - pathology | Adult | Female | Male | Hippocampus - pathology | Case-Control Studies | Physiological aspects | Hippocampus (Brain) | Amygdala (Brain) | Major depressive disorder | Index Medicus | Original
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