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Journal Article
Journal Article
Journal Article
BMC Research Notes, ISSN 1756-0500, 12/2011, Volume 4, Issue 1, pp. 524 - 524
BACKGROUND: To study late-life depression and its unfavourable course and co morbidities in The Netherlands. METHODS: We designed the Netherlands Study of... 
Aged | Research | Comorbidity | Health aspects | Depression, Mental | Prevalence studies (Epidemiology) | Aging | Mental depression | Anxieties | Older people
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 11/2017, Volume 42, Issue 12, pp. 2446 - 2455
Stress responses are controlled by the hypothalamus pituitary adrenal (HPA)-axis and maladaptive stress responses are associated with the onset and maintenance... 
steroid 5alpha reductase 1 | dexamethasone suppression test | nuclear magnetic resonance imaging | single nucleotide polymorphism | lifespan | major clinical study | FKBP5 protein | protein | adrenal gland | hypophysis | female | molecular pathology | major depression | neuropathology | PROP1 protein | cholesterol monooxygenase (side chain cleaving) | child abuse | CYP17A1 protein | mineralocorticoid receptor | article | neuroimaging | hydrocortisone | AVPRA1 protein | multicenter study | transcription factor Pit 1 | adult | male | arousal | unclassified drug | amygdala | cohort analysis | CRH protein | endophenotype | pleiotropy | NR3C2 protein | regulatory mechanism | gene interaction | priority journal | human | mental stress | phenotype | hippocampus | gene mutation | POMC protein | AKR1D1 protein | HSD3B2 protein | brain size | allele | genome-wide association study | hypothalamus | ENVIRONMENT INTERACTION | PSYCHIATRY | BIPOLAR-DISORDER | ALCOHOL-CONSUMPTION | NEUROSCIENCES | MINERALOCORTICOID RECEPTOR | HORMONE | PHARMACOLOGY & PHARMACY | MAJOR DEPRESSIVE DISORDER | INTERNATIONAL DIAGNOSTIC INTERVIEW | PITUITARY-ADRENAL AXIS | GENOME-WIDE ASSOCIATION | AMYGDALA | Endophenotypes - metabolism | Magnetic Resonance Imaging - trends | Pituitary-Adrenal System - metabolism | Humans | Life Change Events | Middle Aged | Hydrocortisone - metabolism | Magnetic Resonance Imaging - methods | Male | Child Abuse - trends | Hippocampus - diagnostic imaging | Hypothalamo-Hypophyseal System - metabolism | Hippocampus - metabolism | Stress, Psychological - genetics | Phenotype | Stress, Psychological - metabolism | Adult | Female | Hypothalamo-Hypophyseal System - diagnostic imaging | Genome-Wide Association Study - methods | Stress, Psychological - diagnostic imaging | Child | Pituitary-Adrenal System - diagnostic imaging | Stresses | Brain | Dexamethasone | Amygdala | Genes | Gene regulation | Disorders | Hypothalamic-pituitary-adrenal axis | Proopiomelanocortin | Single-nucleotide polymorphism | Hypothalamus | Hormones | Mental depression | Hydrocortisone | Gene expression | Substrates | Stress | Pituitary | Diagnosis | Children | Hippocampus | Prophet of pit-1 protein | Original
Journal Article
Journal Article
by Wray, Naomi R and Ripke, Stephan and Mattheisen, Manuel and Trzaskowski, MacIej and Byrne, Enda M and Abdellaoui, Abdel and Adams, Mark J and Agerbo, Esben and Air, Tracy M and Andlauer, Till M. F and Bacanu, Silviu-Alin and Bækvad-Hansen, Marie and Beekman, Aartjan F. T and Bigdeli, Tim B and Binder, Elisabeth B and Blackwood, Douglas R. H and Bryois, Julien and Buttenschøn, Henriette N and Bybjerg-Grauholm, Jonas and Cai, Na and Castelao, Enrique and Christensen, Jane Hvarregaard and Clarke, Toni-Kim and Coleman, Jonathan I. R and Coloo-Conde, Lucía and Couvy-Duchesne, Baptiste and Craddock, Nick and Crawford, Gregory E and Crowley, Cheynna A and Dashti, Hassan S and Davies, Gail and Deary, Ian J and Degenhardt, Franziska and Derks, Eske M and DIrek, Nese and Dolan, Conor V and Dunn, Erin C and Eley, Thalia C and Eriksson, Nicholas and Escott-Price, Valentina and Kiadeh, Farnush Hassan Farhadi and Finucane, Hilary K and Forstner, Aneas J and Frank, Josef and Gaspar, H. léna A and Gill, Michael and Giusti-Roíguez, Paola and Goes, Fernando S and Gordon, Scott D and Grove, Jakob and Hall, Lynsey S and Hannon, Eilis and Hansen, Christine S. holm and Hansen, Thomas F and Herms, Stefan and Hickie, Ian B and Hoffmann, Per and Homuth, Georg and Horn, Carsten and Hottenga, Jouke-Jan and Hougaard, David M and Hu, Ming and Hyde, Craig L and Ising, Marcus and Jansen, Rick and Jin, Fulai and Jorgenson, Eric and Knowles, James A and Kohane, Isaac S and Kraft, Julia and Kretzschmar, Warren W and Krogh, Jesper and Kutalik, Zoltán and Lane, Jacqueline M and Li, Yihan and Li, Yun and Lind, Penelope A and Liu, Xiaoxiao and Lu, Leina and MacIntyre, Donald J and MacKinnon, Dean F and Maier, Robert M and Maier, Wolfgang and Marchini, Jonathan and Mbarek, Hamdi and McGrath, Patrick and McGuffin, Peter and Medland, Sarah E and Mehta, D. Ivya and Middeldorp, Christel M and Mihailov, Evelin and Milaneschi, Yuri and Milani, Lili and Mill, Jonathan and Mondimore, Francis M and Montgomery, Grant W and Mostafavi, Sara and Mullins, Niamh and Nauck, Matthias and Ng, Bernard and ... and Major Depressive Disorder Working and EQTLGEN and eQTLGen and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium and 23andMe and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Nature genetics, ISSN 1061-4036, 2018, Volume 50, Issue 5, pp. 668 - 681
Major depressive disorder (MDD) is a common illness accompanied by considerable morbidity, mortality, costs, and heightened risk of suicide. We conducted a... 
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