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Journal of Biological Chemistry, ISSN 0021-9258, 02/2014, Volume 289, Issue 6, pp. 3352 - 3364
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e47931
The unfolded protein response (UPR) is regulated by three ER-localized, transmembrane signal transducers that control distinct aspects of the UPR. We... 
RNA | Etoposide | Drug resistance
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 9, pp. 1 - 13
Background: Inadequate extracellular conditions can adversely affect the environment of the ER and impinge on the maturation of nascent proteins. The resultant... 
FACTOR XBP-1 | IN-VIVO | BIOLOGY | ENDOPLASMIC-RETICULUM STRESS | MESSENGER-RNA STABILITY | PLASMA-CELL DIFFERENTIATION | NF-KAPPA-B | TUMOR-GROWTH | ANGIOGENIC FACTORS | ENDOTHELIAL GROWTH-FACTOR | TRANSMEMBRANE PROTEIN | Cell Line | Interleukin-8 - genetics | Promoter Regions, Genetic | Up-Regulation | Humans | Ribonuclease, Pancreatic - genetics | Transcriptional Activation | Endoplasmic Reticulum - metabolism | Rats | Vascular Endothelial Growth Factor A - metabolism | Unfolded Protein Response | Vascular Endothelial Growth Factor A - genetics | Mice, Knockout | Animals | Fibroblast Growth Factor 2 - genetics | Ribonuclease, Pancreatic - metabolism | Angiogenesis Inducing Agents - metabolism | Fibroblast Growth Factor 2 - metabolism | Transcription, Genetic | Mice | Protein Processing, Post-Translational | Interleukin-8 - metabolism | Neovascularization, Physiologic | RNA | Analysis | Physiological aspects | Cellular signal transduction | Genetic aspects | Fibroblast growth factors | Genetic transcription | Vascular endothelial growth factor | Post-transcription | Regulators | Transcription factors | Gene regulation | Science | Homeostasis | Biology | Activation | Kinases | Angiogenin | Proteins | Angiogenesis | Signal transduction | Thapsigargin | Protein folding | Rodents | Cell cycle | Post-translation | Fibroblasts | Physiology | Interleukin 8 | Inducers | Fibroblast growth factor 2 | Stresses | Cues | Enzymes | AMP | Embryo fibroblasts | Embryos | Stress | Children & youth | DNA microarrays | Placenta | Medulloblastoma | Cell lines | Hypoxia | Transduction | Human behavior | Endoplasmic reticulum | mRNA stability | Cancer | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 3022 - 3022
Journal Article
Nature Protocols, ISSN 1754-2189, 08/2017, Volume 12, Issue 8, pp. 1513 - 1520
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, pp. e47931 - e47931
Background: The unfolded protein response (UPR) is regulated by three ER-localized, transmembrane signal transducers that control distinct aspects of the UPR.... 
CANCER-CELLS | GLUCOSE-REGULATED PROTEINS | UNFOLDED-PROTEIN RESPONSE | ER STRESS | MULTIDISCIPLINARY SCIENCES | ENDOPLASMIC-RETICULUM STRESS | CELL-CYCLE PROGRESSION | NF-KAPPA-B | MAMMALIAN-CELLS | TRANSCRIPTION FACTOR | TRANSMEMBRANE PROTEIN | NIH 3T3 Cells | Endoribonucleases - genetics | eIF-2 Kinase - metabolism | Humans | Cell Survival - genetics | Activating Transcription Factor 6 - genetics | X-Box Binding Protein 1 | DNA-Binding Proteins - metabolism | HEK293 Cells | Antigens, Neoplasm - metabolism | Cell Cycle Checkpoints - genetics | Drug Resistance | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | eIF-2 Kinase - genetics | Cell Survival - drug effects | DNA Topoisomerases, Type II - metabolism | Endoribonucleases - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Activating Transcription Factor 4 - genetics | Etoposide - pharmacology | Topoisomerase II Inhibitors - pharmacology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Unfolded Protein Response | Regulatory Factor X Transcription Factors | Blotting, Western | Mice, Knockout | Transcription Factors - metabolism | Activating Transcription Factor 6 - metabolism | Animals | Activating Transcription Factor 4 - metabolism | Cell Cycle Checkpoints - drug effects | Embryo, Mammalian - cytology | Fibroblasts - drug effects | Cell Line, Tumor | Thapsigargin - pharmacology | Mice | Transducers | Phosphorylation | Transcription factors | Transcription | Science | Etoposide | Homeostasis | Activation | Drug resistance | Kinases | Proteins | Signal transduction | Sensitivity | Protein folding | Protein synthesis | Rodents | Cell cycle | Hypoxia | Endoplasmic reticulum | Cancer | Apoptosis | Index Medicus
Journal Article
FASEB Journal, ISSN 0892-6638, 09/2015, Volume 29, Issue 9, pp. 3668 - 3677
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 01/2015, Volume 191, p. 1
Journal Article
2012, 2012, ISBN 9400743505, Volume 9789400743519
Due to their rapid growth, tumors are frequently exposed to extracellular environments that are deficient in nutrients, low in oxygen and with sub-optimal pH.... 
Biomedicine | Immunology | Cell Physiology | Molecular Medicine | Biomedicine general | Cell Biology | Apoptosis | Unfolded Protein Response (UPR) | Angiogenesis | VEGF | Chemosensitivity | Etoposide | mTOR | 4E-BP1 | Topo IIa | Translation Control
Book Chapter
Frontiers in Oncology, ISSN 2234-943X, 02/2018, Volume 8, pp. 36 - 36
Journal Article