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The EMBO Journal, ISSN 0261-4189, 02/2011, Volume 30, Issue 3, pp. 494 - 509
TAL1/SCL is a master regulator of haematopoiesis whose expression promotes opposite outcomes depending on the cell type: differentiation in the erythroid... 
erythroid cells | SCL/TAL1 | T‐cell acute lymphoblastic leukaemia (T‐ALL) | ETS1 | RUNX1 | T-cell acute lymphoblastic leukaemia (T-ALL) | APOPTOSIS | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ERYTHROID-CELLS | CELL BIOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | DEPENDENT KINASE 6 | WIDE ANALYSIS | GENE-EXPRESSION | POSITIVE ROLE | SCL | BINDING | Proto-Oncogene Protein c-ets-1 - metabolism | Humans | Molecular Sequence Data | Gene Expression Profiling | Cell Differentiation - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Chromatin Immunoprecipitation | T-Lymphocytes - metabolism | Cell Transformation, Neoplastic - genetics | Microarray Analysis | Base Sequence | Leukemia, T-Cell - metabolism | Hematopoiesis - physiology | T-Cell Acute Lymphocytic Leukemia Protein 1 | Proto-Oncogene Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Core Binding Factor Alpha 2 Subunit - metabolism | Jurkat Cells | Cells, Cultured | Hematopoiesis - genetics | Proto-Oncogene Proteins - genetics | Binding Sites - genetics | Reverse Transcriptase Polymerase Chain Reaction | Sequence Analysis, DNA | Leukemia, T-Cell - genetics | T-Lymphocytes - cytology | Proto-Oncogene Protein c-ets-1 - genetics | Core Binding Factor Alpha 2 Subunit - genetics | T cell receptors | Molecular biology | Gene expression | Genomics | Binding sites | Index Medicus | TAL1
Journal Article
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 02/2012, Volume 80, Issue 2, pp. 374 - 381
Circular dichroism (CD) is a spectroscopic technique commonly used to investigate the structure of proteins. Major secondary structure types, alpha‐helices and... 
web tool | spectroscopy | algorithm | Spectroscopy | Algorithm | Web tool | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Algorithms | Internet | Proteins - chemistry | Protein Structure, Secondary | Circular Dichroism | Databases, Protein | Proteins | Stem cell research | Sound recordings | Usage | Stem cells | Index Medicus
Journal Article
Journal Article
INTERNATIONAL JOURNAL OF CANCER, ISSN 0020-7136, 09/2014, Volume 135, Issue 5, pp. 1072 - 1084
Exogenous 17 beta-estradiol (E2) accelerates the progression of ovarian cancer in the transgenic tgCAG-LS-TAg mouse model of the disease. We hypothesized that... 
estrogen | HORMONE-THERAPY | mouse model | ovarian cancer | GREB1 | RISK | BREAST-CANCER CELLS | microarray | MESSENGER-RIBONUCLEIC-ACID | ONCOLOGY | STANNIOCALCIN-2 | ESTROGEN-RECEPTOR-ALPHA | GROWTH | ESTRADIOL | SURFACE EPITHELIAL-CELLS | GENE-EXPRESSION
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 12/2012, Volume 80, Issue 12, pp. 2818 - 2818
Journal Article
Circulation, ISSN 0009-7322, 12/2017, Volume 136, Issue 25, pp. 2451 - 2467
BACKGROUND: Pulmonary arterial hypertension (PAH) is characterized by abnormal growth and enhanced glycolysis of pulmonary artery endothelial cells. However,... 
microRNAs | hypertension, pulmonary | endothelial cells | metabolism | endothelial progenitor cells | glycolysis | APOPTOSIS | COACTIVATOR | CARDIAC & CARDIOVASCULAR SYSTEMS | hypertension pulmonary | TUMOR | INHIBITION | MIR-124 | GROWTH | PERIPHERAL VASCULAR DISEASE | EXPRESSION | Cell Proliferation | MicroRNAs - antagonists & inhibitors | Humans | MicroRNAs - metabolism | Polypyrimidine Tract-Binding Protein - antagonists & inhibitors | Familial Primary Pulmonary Hypertension - metabolism | Lim Kinases - metabolism | Monocarboxylic Acid Transporters - metabolism | RNA Interference | Smad5 Protein - metabolism | Bone Morphogenetic Protein Receptors, Type II - antagonists & inhibitors | Disease Models, Animal | Familial Primary Pulmonary Hypertension - pathology | Bone Morphogenetic Protein Receptors, Type II - genetics | Pyruvate Kinase - metabolism | Endothelial Cells - metabolism | Cells, Cultured | Heterogeneous-Nuclear Ribonucleoproteins - metabolism | Rats | Familial Primary Pulmonary Hypertension - genetics | Heterogeneous-Nuclear Ribonucleoproteins - antagonists & inhibitors | Polypyrimidine Tract-Binding Protein - metabolism | Bone Morphogenetic Protein Receptors, Type II - metabolism | Symporters - metabolism | Heterogeneous-Nuclear Ribonucleoproteins - genetics | Animals | Endothelial Cells - cytology | Glycolysis | Smad1 Protein - metabolism | MicroRNAs - genetics | Antagomirs - metabolism | Pyruvate Kinase - genetics | Polypyrimidine Tract-Binding Protein - genetics | RNA, Small Interfering - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 07/2009, Volume 28, Issue 30, pp. 2710 - 2722
The role of the canonical NF-[kappa]B pathway in mammary tumorigenesis was investigated using a transgenic (TG) mouse expressing a dominant-negative inhibitor... 
Basal | Squamous | Luminal | Mammary cancer | NF-kB | Transgenic mice | Physiological aspects | Development and progression | Breast cancer | Genetic aspects | Research | DNA binding proteins | Genetic regulation | Properties | Risk factors | Genetics | Transgenic animals | Rodents | Stem cells | Flow cytometry | NF-B protein | Transformation | Data processing | Carcinogenesis | Promoters | Metaplasia | Tumorigenesis | Mammary gland | Neoplasia | Islands | Cancer
Journal Article
Thorax, ISSN 0040-6376, 12/2016, Volume 71, Issue Suppl 3, pp. A48 - A49
IntroductionPulmonary arterial hypertension (PAH) is a rare desease characterised by profound vascular abnormalities in the peripheral arteries of the lung,... 
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 02/2011, Volume 20, Issue 4, pp. 731 - 751
Mammalian circadian rhythms are synchronized to the external time by daily resetting of the suprachiasmatic nucleus (SCN) in response to light. As the master... 
RESPONSE ELEMENT | POLY(A) BINDING-PROTEIN | MESSENGER-RNA | RETT-SYNDROME | SUPRACHIASMATIC NUCLEUS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SLEEP PHASE SYNDROME | GENETICS & HEREDITY | GENE-EXPRESSION | POLY(A)-BINDING PROTEIN | HISTONE ACETYLTRANSFERASE | ACTIVE GENES | NIH 3T3 Cells | Humans | Methyl-CpG-Binding Protein 2 - metabolism | Chromatin Assembly and Disassembly - genetics | MicroRNAs - metabolism | E1A-Associated p300 Protein - metabolism | Chromatin Assembly and Disassembly - drug effects | Retinoblastoma-Binding Protein 2 - metabolism | Immediate-Early Proteins - metabolism | Period Circadian Proteins - genetics | Light | HEK293 Cells | Suprachiasmatic Nucleus - metabolism | DNA-Binding Proteins | Tumor Suppressor Proteins - metabolism | Signal Transduction | Mice, Inbred C57BL | Circadian Rhythm - genetics | Computational Biology | Gene Expression Regulation | Mice, Transgenic | RNA Stability | Animals | Period Circadian Proteins - metabolism | Mice | MicroRNAs - genetics | Jumonji Domain-Containing Histone Demethylases | Index Medicus | Suprachiasmatic nucleus | Calcium | Transcription | CLOCK protein | BTG2 protein | Period 1 protein | Methyl-CpG binding protein | Entrainment | miRNA | Period 2 protein | Circadian rhythms | Obesity | Translation | mRNA turnover | Cyclic AMP | Light effects | Oscillators | Promoters | Chromatin remodeling | Neurological diseases | Period protein | Sleep | MeCP2 protein | Workers | Pacemakers | Cardiovascular diseases | Cancer
Journal Article
BMC Structural Biology, ISSN 1472-6807, 2008, Volume 8, Issue 1, pp. 25 - 25
Background: Circular dichroism spectroscopy is a widely used technique to analyze the secondary structure of proteins in solution. Predictive methods use the... 
BIOPHYSICS | Software | Algorithms | Internet | Protein Structure, Secondary | Circular Dichroism - statistics & numerical data | Computational Biology | Proteins | Measurement | Usage | Spectrum analysis | Physiological aspects | Research | Structure | Circular dichroism | Index Medicus
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 05/2011, Volume 30, Issue 9, pp. 1778 - 1789
Journal Article
Oncogene, ISSN 0950-9232, 07/2009, Volume 28, Issue 30, pp. 2710 - 2722
The role of the canonical NF-kappa B pathway in mammary tumorigenesis was investigated using a transgenic (TG) mouse expressing a dominant-negative inhibitor... 
CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | ALPHA | HUMAN BREAST-CANCER | luminal | basal | TUMORS | CELL BIOLOGY | squamous | ONCOLOGY | THERAPEUTIC TARGET | GROWTH | GENETICS & HEREDITY | mammary cancer | EXPRESSION | NF-kappa B; transgenic mice | GLAND | TRANSGENIC MICE
Journal Article