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Genome Biology, ISSN 1474-7596, 03/2019, Volume 20, Issue 1, pp. 52 - 52
We propose a statistical boosting method, termed I-Boost, to integrate multiple types of high-dimensional genomics data with clinical data for predicting... 
Gene modules | Data integration | Cancer genomics | Variable selection | REGRESSION | MODEL | BREAST-CANCER | LUNG-CANCER | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | REGULARIZATION | SELECTION | JOINT | AGE | Genomics | Genomes | Breast cancer | Research | Gene expression | Patients | Survival | Variables | Accuracy | DNA methylation | Deoxyribonucleic acid--DNA | Methods | Tumors | Cancer
Journal Article
by Thorsson, Vesteinn and Thorsson, Vésteinn and Gibbs, Richard A and Gibbs, David L and Brown, Scott D and Wolf, Gregory and Wolf, Denise and Bortone, Dante S and Ou Yang, Tai-Hsien and Porta-Pardo, Eduard and Gao, Galen F and Gao, Jianjiong and Plaisier, Christopher L and Eddy, James A and Ziv, Elad and Culhane, Aedin C and Paull, Evan O and Sivakumar, I.K. Ashok and Gentles, Andrew J and Malhotra, Raunaq and Farshidfar, Farshad and Colaprico, Antonio and Parker, Joel S and Mose, Lisle E and Vo, Nam Sy and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Rader, Janet and Dhankani, Varsha and Reynolds, Sheila and Reynolds, Sheila M and Bowlby, Reanne and Califano, Andrea and Cherniack, Andrew D and Anastassiou, Dimitris and Bedognetti, Davide and Mokrab, Younes and Newman, Aaron M and Rao, Arvind and Chen, Amy and Chen, Chu and Chen, Ken and Krasnitz, Alexander and Hu, Jianhong and Hu, Hai and Malta, Tathiane M and Noushmehr, Houtan and Pedamallu, Chandra Sekhar and Bullman, Susan and Ojesina, Akinyemi I and Lamb, Andrew and Zhou, Wanding and Shen, Hui and Choueiri, Toni K and Weinstein, John N and Guinney, Justin and Saltz, Joel and Holt, Robert and Holt, Robert A and Rabkin, Charles S and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jioajiao and Wang, Min and Wang, Linghua and Wang, Zhining and Wang, Timothy and Wang, Jing and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Yang, Ian and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Jiexin and Zhang, Lizhi and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 812 - 830.e14
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across... 
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory | GENOMIC ANALYSES | INFORMATION | T-CELL-RECEPTOR | REGULATORY NETWORK | CLASSIFICATION | IMMUNOLOGY | SEQUENCING DATA | SOMATIC MUTATIONS | COMPREHENSIVE ANALYSIS | PREDICTION | REVEALS | Transforming Growth Factor beta - immunology | Prognosis | Humans | Middle Aged | Th1-Th2 Balance - physiology | Male | Neoplasms - classification | Wound Healing - immunology | Young Adult | Transforming Growth Factor beta - genetics | Neoplasms - genetics | Neoplasms - immunology | Interferon-gamma - immunology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Interferon-gamma - genetics | Wound Healing - genetics | Genomics - methods | Child | Macrophages - immunology | Cell proliferation | Cluster analysis | Transcription | Copy number | p53 Protein | Lung cancer | Genomics | Aneuploidy | Lymphocytes T | Genomes | Cell interactions | Macrophages | Immunotherapy | DNA methylation | Deoxyribonucleic acid--DNA | Immune system | Medical research | Wound healing | Immunomodulation | MiRNA | Stockholders | Inflammation | T cell receptors | Communications networks | Gene expression | White blood cells | Inventors | Medical prognosis | γ-Interferon | Mutation | Cancer | Tumors | Index Medicus | Immune Subtypes | Integrative Network Analysis | Cancer Genomics | Immuno-oncology | Tumor immunology
Journal Article
Bioinformatics (Oxford, England), ISSN 1367-4803, 01/2019
Genomic variant detection from next-generation sequencing (NGS) has become established as an extremely important component of research and clinical diagnoses... 
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2015, Volume 21, Issue 8, pp. 1779 - 1781
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. PL01-03 - PL01-03
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 04/2015, Volume 107, Issue 4
Journal Article
by Akbani, Rehan and Akdemir, Kadir C and Aksoy, B. Arman and Albert, Monique and Ally, Adrian and Amin, Samirkumar B and Arachchi, Harindra and Arora, Arshi and Auman, J. Todd and Ayala, Brenda and Baboud, Julien and Balasundaram, Miruna and Balu, Saianand and Barnabas, Nandita and Bartlett, John and Bartlett, Pam and Bastian, Boris C and Baylin, Stephen B and Behera, Madhusmita and Belyaev, Dmitry and Benz, Christopher and Bernard, Brady and Beroukhim, Rameen and Bir, Natalie and Black, Aaron D and Bodenheimer, Tom and Boice, Lori and Boland, Genevieve M and Bono, Riccardo and Bootwalla, Moiz S and Bosenberg, Marcus and Bowen, Jay and Bowlby, Reanne and Bristow, Christopher A and Brockway-Lunardi, Laura and Brooks, Denise and Brzezinski, Jakub and Bshara, Wiam and Buda, Elizabeth and Burns, William R and Butterfield, Yaron S.N and Button, Michael and Calderone, Tiffany and Cappellini, Giancarlo Antonini and Carter, Candace and Carter, Scott L and Cherney, Lynn and Cherniack, Andrew D and Chevalier, Aaron and Chin, Lynda and Cho, Juok and Cho, Raymond J and Choi, Yoon-La and Chu, Andy and Chudamani, Sudha and Cibulskis, Kristian and Ciriello, Giovanni and Clarke, Amanda and Coons, Stephen and Cope, Leslie and Crain, Daniel and Curley, Erin and Danilova, Ludmila and D’Atri, Stefania and Davidsen, Tanja and Davies, Michael A and Delman, Keith A and Demchok, John A and Deng, Qixia A and Deribe, Yonathan Lissanu and Dhalla, Noreen and Dhir, Rajiv and DiCara, Daniel and Dinikin, Michael and Dubina, Michael and Ebrom, J. Stephen and Egea, Sophie and Eley, Greg and Engel, Jay and Eschbacher, Jennifer M and Fedosenko, Konstantin V and Felau, Ina and Fennell, Timothy and Ferguson, Martin L and Fisher, Sheila and Flaherty, Keith T and Frazer, Scott and Frick, Jessica and Fulidou, Victoria and Gabriel, Stacey B and Gao, Jianjiong and Gardner, Johanna and Garraway, Levi A and Gastier-Foster, Julie M and Gaudioso, Carmelo and Gehlenborg, Nils and Genovese, Giannicola and Gerken, Mark and Gershenwald, Jeffrey E and Getz, Gad and ... and Canc Genome Atlas Network and Cancer Genome Atlas Network
Cell, ISSN 0092-8674, 06/2015, Volume 161, Issue 7, pp. 1681 - 1696
Journal Article