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Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, pp. e73121 - e73121
G-quadruplexes are tetraplex structures of nucleic acids that can form in G-rich sequences. Their presence and functional role have been established in... 
TELOMERIC G-QUADRUPLEX | CATIONIC PORPHYRINS | DNA QUADRUPLEX | MESSENGER-RNA | GENE | MULTIDISCIPLINARY SCIENCES | LOOP | IMMUNODEFICIENCY-VIRUS TYPE-1 | GENOME-WIDE | I-MOTIF STRUCTURES | CONSERVED CORE | Gene Expression Regulation, Viral - physiology | GC Rich Sequence - physiology | HIV Infections - genetics | Humans | nef Gene Products, Human Immunodeficiency Virus - chemistry | HIV-1 - physiology | nef Gene Products, Human Immunodeficiency Virus - genetics | HIV-1 - chemistry | HEK293 Cells | HIV Infections - therapy | nef Gene Products, Human Immunodeficiency Virus - metabolism | Virus Replication - physiology | HIV Infections - metabolism | Antiviral agents | Telomeres | Viral proteins | Analysis | Genes | Development and progression | Genetic aspects | Nucleic acids | Genetic transcription | HIV (Viruses) | Transcription | Incubation | Pathogenesis | Gene regulation | Viruses | Genomes | Kinases | Gene expression | Proteins | Medicine | Reporter gene | Nef protein | Acquired immune deficiency syndrome--AIDS | Infectivity | Human immunodeficiency virus--HIV | Computer applications | Antiviral activity | Ligands | In vivo methods and tests | Telomerase | Deoxyribonucleic acid--DNA | Viral infections | Index Medicus | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | DNA | Human immunodeficiency virus
Journal Article
Head & Neck, ISSN 1043-3074, 06/2019, Volume 41, Issue 6, pp. 1895 - 1902
Background In clinical trials of recurrent and metastatic head and neck carcinoma, Argiris et al have identified prognostic factors for overall survival (OS)... 
recurrence | head and neck cancer | classification | prognosis | squamous cell carcinoma | SURVIVAL | SURGERY | HUMAN-PAPILLOMAVIRUS | FLUOROURACIL | CHEMOTHERAPY | CISPLATIN | OTORHINOLARYNGOLOGY | SALVAGE SURGERY | Squamous cell carcinoma | Prognosis | Metastasis | Papillomavirus infections | Analysis | Medical prognosis | Classification | Clinical trials | Head and neck cancer | Radiation therapy | Neck | Metastases
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2013, Volume 56, Issue 16, pp. 6521 - 6530
G-Quadruplexes, noncanonical nucleic acid structures, act as silencers in the promoter regions of human genes; putative G-quadruplex forming sequences are also... 
CHEMISTRY, MEDICINAL | CIRCULAR-DICHROISM | FORMING SEQUENCES | TAT | ESCHERICHIA-COLI | TRANSCRIPTION | LOOP | IMMUNODEFICIENCY-VIRUS TYPE-1 | DNA MOTIFS | GENOME-WIDE | DIMERIZATION | HIV Long Terminal Repeat - genetics | Promoter Regions, Genetic | G-Quadruplexes | HIV-1 - genetics | Humans | HEK293 Cells | Index Medicus
Journal Article
by De Placido, Sabino and Gallo, Ciro and De Laurentiis, Michelino and Bisagni, Giancarlo and Arpino, Grazia and Sarobba, Maria Giuseppa and Riccardi, Ferdinando and Russo, Antonio and Del Mastro, Lucia and Cogoni, Alessio Aligi and Cognetti, Francesco and Gori, Stefania and Foglietta, Jennifer and Frassoldati, Antonio and Amoroso, Domenico and Laudadio, Lucio and Moscetti, Luca and Montemurro, Filippo and Verusio, Claudio and Bernardo, Antonio and Lorusso, Vito and Gravina, Adriano and Moretti, Anna and Moretti, Gabriella and Lauria, Rossella and Lai, Antonella and Mocerino, Carmela and Rizzo, Sergio and Nuzzo, Antonio and Nuzzo, Francesco and Carlini, Paolo and Perrone, Francesco and Accurso, Antonello and Agostara, Biagio and Aieta, Michele and Alabiso, Oscar and Alicicco, Maria Grazia and Amadori, Dino and Amaducci, Laura and Amiconi, Gianna and Antuzzi, Giustino and Ardine, Mara and Ardizzoia, Antonio and Aversa, Caterina and Badalamenti, Giuseppe and Barni, Sandro and Basurto, Carlo and Berardi, Rossana and Bergamasco, Cinzia and Bidoli, Paolo and Bighin, Claudia and Biondi, Edoardo and Boni, Corrado and Borgonovo, Karen and Botta, Mario and Bravi, Stefano and Bruzzi, Paolo and Buono, Giuseppe and Butera, Alfredo and Caldara, Alessia and Candeloro, Giampiero and Cappelletti, Claudia and Cardalesi, Cinzia and Carfora, Elisabetta and Cariello, Anna and Carrozza, Francesco and Cartenì, Giacomo and Caruso, Michele and Casadei, Virginia and Casanova, Claudia and Castori, Luigi and Cavanna, Luigi and Cavazzini, Giovanna and Cazzaniga, Marina and Chilelli, Mario and Chiodini, Paolo and Chiorrini, Silvia and Ciardiello, Fortunato and Ciccarese, Mariangela and Cinieri, Saverio and Clerico, Mario and Coccaro, Mariarosa and Comande, Mario and Corbo, Claudia and Cortino, Giuseppina and Cusenza, Stefania and Daniele, Gennaro and D'arco, Alfonso Maria and D'auria, Giuliana and Dazzi, Claudio and De Angelis, Carmine and de Braud, Filippo and De Feo, Gianfranco and De Matteis, Andrea and De Tursi, Michele and Di Blasio, Anna and di Lucca, Giuseppe and Di Lullo, Liberato and Di Rella, Francesca and Di Renzo, Gianfranco and ... and GIM Investigators
The Lancet Oncology, ISSN 1470-2045, 04/2018, Volume 19, Issue 4, pp. 474 - 485
Uncertainty exists about the optimal schedule of adjuvant treatment of breast cancer with aromatase inhibitors and, to our knowledge, no trial has directly... 
SYSTEM | THERAPY | EFFICACY | ONCOLOGY | FOLLOW-UP | POSTMENOPAUSAL WOMEN | COMBINATION | AROMATASE INHIBITORS | Breast cancer | Product development | Tamoxifen | Analysis | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, pp. e92147 - e92147
Introduction: Although cetuximab and panitumumab show an increased efficacy for patients with KRAS-NRAS-BRAF and PI3KCA wild-type metastatic colorectal cancer,... 
CELL LUNG-CANCER | ANAPLASTIC LYMPHOMA KINASE | PHASE-III TRIAL | GROWTH-FACTOR RECEPTOR | 1ST-LINE TREATMENT | CETUXIMAB | SOLID TUMORS | RAS MUTATIONS | MULTIDISCIPLINARY SCIENCES | KRAS | MONOCLONAL-ANTIBODIES | Demography | Membrane Proteins - genetics | Humans | Middle Aged | In Situ Hybridization, Fluorescence | Male | Treatment Outcome | Gene Dosage | Transcription Factors - genetics | Disease-Free Survival | Receptor, Epidermal Growth Factor - metabolism | Receptor Protein-Tyrosine Kinases - genetics | GTP Phosphohydrolases - genetics | Proto-Oncogene Proteins B-raf - genetics | Colorectal Neoplasms - drug therapy | Aged, 80 and over | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Adult | Female | Aged | Nuclear Proteins - genetics | Care and treatment | Patient outcomes | Colorectal cancer | Development and progression | Genetic aspects | Research | Biological markers | Securitization | Copy number | Lung cancer | Colorectal carcinoma | ALK protein | Raf protein | Oncology | Systematic review | Metastasis | Kinases | Cancer therapies | Clinical outcomes | K-Ras protein | Metastases | Signal transduction | Epidermal growth factor | DNA methylation | Deoxyribonucleic acid--DNA | Translocation | Epidermal growth factor receptors | Patients | Survival | Amplification | Pathology | Irinotecan | Gene amplification | Chemotherapy | Medical prognosis | Response rates | Biomarkers | Lymphomas | Tumors | Cancer | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article