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science & technology (97) 97
life sciences & biomedicine (93) 93
humans (71) 71
pulmonary hypertension (58) 58
respiratory system (46) 46
animals (35) 35
abridged index medicus (31) 31
life sciences (31) 31
male (31) 31
cardiovascular system & cardiology (26) 26
pulmonary arterial hypertension (25) 25
cardiac & cardiovascular systems (24) 24
female (24) 24
hypertension, pulmonary - physiopathology (23) 23
general & internal medicine (22) 22
hypertension (21) 21
hypertension, pulmonary - metabolism (21) 21
critical care medicine (20) 20
inflammation (20) 20
hypertension, pulmonary - pathology (19) 19
endothelial cells (18) 18
rats (17) 17
risk factors (17) 17
cell proliferation (16) 16
disease models, animal (16) 16
middle aged (15) 15
peripheral vascular disease (15) 15
pulmonary artery - pathology (15) 15
research (15) 15
familial primary pulmonary hypertension (14) 14
human health and pathology (14) 14
pulmonary arteries (14) 14
adult (13) 13
biological and medical sciences (13) 13
case-control studies (13) 13
hypertension, pulmonary - drug therapy (13) 13
medical sciences (13) 13
smooth muscle (13) 13
[sdv]life sciences [q-bio] (12) 12
cell biology (12) 12
cells, cultured (12) 12
hypertension, pulmonary (12) 12
pulmonary artery - metabolism (12) 12
analysis (11) 11
gene expression (11) 11
pneumology (11) 11
pulmonary hypertension. acute cor pulmonale. pulmonary embolism. pulmonary vascular diseases (11) 11
veins & arteries (11) 11
cardiology and cardiovascular system (10) 10
care and treatment (10) 10
health aspects (10) 10
hypertension, pulmonary - chemically induced (10) 10
hypertension, pulmonary - genetics (10) 10
pulmonary artery (10) 10
biochemistry & molecular biology (9) 9
heart (9) 9
hypertension, pulmonary - immunology (9) 9
pulmonary artery - physiopathology (9) 9
signal transduction (9) 9
apoptosis (8) 8
genetic aspects (8) 8
mice (8) 8
monocrotaline (8) 8
muscle, smooth, vascular - metabolism (8) 8
mutation (8) 8
myocytes, smooth muscle - metabolism (8) 8
pathology (8) 8
rodents (8) 8
[sdv.mhep.csc]life sciences [q-bio]/human health and pathology/cardiology and cardiovascular system (7) 7
aged (7) 7
anesthesia. intensive care medicine. transfusions. cell therapy and gene therapy (7) 7
cancer (7) 7
gene mutations (7) 7
hypertension, pulmonary - diagnosis (7) 7
intensive care medicine (7) 7
lung - metabolism (7) 7
lung - pathology (7) 7
lung diseases (7) 7
myocytes, smooth muscle (7) 7
physiological aspects (7) 7
proteins (7) 7
pulmonary veno-occlusive disease (7) 7
bone morphogenetic protein receptors, type ii - genetics (6) 6
cellular biology (6) 6
dendritic cells (6) 6
development and progression (6) 6
endothelium (6) 6
endothelium, vascular - physiopathology (6) 6
genetic predisposition to disease (6) 6
hypertension, pulmonary - etiology (6) 6
lung (6) 6
lungs (6) 6
platelet-derived growth factor (6) 6
rats, wistar (6) 6
smooth muscle cells (6) 6
asthma (5) 5
cardiology and cardiovascular medicine (5) 5
cell proliferation - drug effects (5) 5
chemokines (5) 5
endothelial cells - metabolism (5) 5
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1. Full Text House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
by Lambrecht, Bart N and Willart, Monique A and Germain, Ronald N and Hammad, Hamida and Chieppa, Marcello and Perros, Frederic
Nature medicine, ISSN 1078-8956, 04/2009, Volume 15, Issue 4, pp. 410 - 416
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Humans | Neutrophils - immunology | Hypersensitivity - immunology | Toll-Like Receptor 4 - genetics | Stromal Cells - immunology | Toll-Like Receptor 4 - immunology | Immunity, Innate | Lipopolysaccharides - adverse effects | Lipopolysaccharides - immunology | Mice, Knockout | Animals | Allergens - immunology | Toll-Like Receptor 4 - deficiency | Asthma - immunology | Mice | Toll-Like Receptor 4 - antagonists & inhibitors | Pyroglyphidae - immunology | Allergens | Allergy | House-dust mite | Research | T cells | Allergic reaction | Risk factors | Asthma | Complications and side effects | Antigen receptors, T cell | Receptors | Physiological aspects | Health aspects | Medical research | Cellular biology | Insects | Allergies | Index Medicus
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2. Full Text TLR4 signalling in pulmonary stromal cells is critical for inflammation and immunity in the airways
by Perros, Frederic and Lambrecht, Bart N and Hammad, Hamida
Respiratory research, ISSN 1465-9921, 12/2011, Volume 12, Issue 1, pp. 1 - 8
pulmonary stromal cells | Pneumology/Respiratory System | dendritic cells | Medicine & Public Health | Airway diseases | epithelial cell | TLR4 | Epithelial cell | Pulmonary stromal cells | Dendritic cells | Life Sciences & Biomedicine | Respiratory System | Science & Technology | Stromal Cells - pathology | Humans | Stromal Cells - metabolism | Pneumonia - pathology | Respiratory Mucosa - pathology | Toll-Like Receptor 4 - physiology | Immunity, Cellular - immunology | Immunity, Innate - immunology | Signal Transduction - immunology | Animals | Respiratory Mucosa - immunology | Pneumonia - immunology | Respiratory Mucosa - metabolism | Pneumonia - metabolism | Stromal Cells - cytology | Transcription factors | Cell receptors | Physiological aspects | Respiratory tract diseases | Genetic aspects | Cellular signal transduction | Research | Risk factors | Inflammation | B cells | Health aspects | Asthma | Proteins | Signal transduction | Rodents | Mortality | Ligands | Ventilation | Chemokines | Index Medicus | Review
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3. Full Text Increased oxidative stress and severe arterial remodeling induced by permanent high-flow challenge in experimental pulmonary hypertension
by Dorfmüller, Peter and Chaumais, Marie-Camille and Giannakouli, Maria and Durand-Gasselin, Ingrid and Raymond, Nicolas and Fadel, Elie and Mercier, Olaf and Charlotte, Frédéric and Montani, David and Simonneau, Gérald and Humbert, Marc and Perros, Frédéric
Respiratory research, ISSN 1465-9921, 12/2011, Volume 12, Issue 1, pp. 1 - 17
Medicine & Public Health | Pneumology/Respiratory System | Life Sciences & Biomedicine | Respiratory System | Science & Technology | Oxidative Stress - physiology | Hypertension, Pulmonary - physiopathology | Rats | Male | Hypertension, Pulmonary - metabolism | Random Allocation | Rats, Sprague-Dawley | Pulmonary Artery - metabolism | Animals | Endothelium, Vascular - metabolism | Endothelium, Vascular - pathology | Airway Remodeling - physiology | Blood Flow Velocity - physiology | Pulmonary Artery - pathology | Disease Models, Animal | Polymerase chain reaction | Oxidative stress | Usage | Physiological aspects | Genetic aspects | Research | Diagnosis | Pulmonary hypertension | Risk factors | Enzymes | Operating systems | Dendritic cells | Analysis | Atherosclerosis | Superoxide | Inflammation | Hypertension | Proteins | Pulmonary arteries | Rodents | Veins & arteries | Index Medicus | Life Sciences | Human health and pathology | Pulmonology and respiratory tract
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4. Full Text miR-223 reverses experimental pulmonary arterial hypertension
by Meloche, Jolyane and Le Guen, Marie and Potus, François and Vinck, Jérôme and Ranchoux, Benoit and Johnson, Ian and Antigny, Fabrice and Tremblay, Eve and Breuils-Bonnet, Sandra and Perros, Frederic and Provencher, Steeve and Bonnet, Sébastien
American Journal of Physiology: Cell Physiology, ISSN 0363-6143, 09/2015, Volume 309, Issue 6, pp. C363 - C372
MiR-223 | HIF-1α | PARP-1 | DNA damage | Pulmonary hypertension | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Muscle, Smooth, Vascular - metabolism | Humans | Middle Aged | Monocrotaline - pharmacology | Apoptosis - genetics | Male | MicroRNAs - metabolism | Hypertension, Pulmonary - chemically induced | Pulmonary Artery - metabolism | DNA Damage - physiology | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Female | Lung - metabolism | Myocytes, Smooth Muscle - drug effects | Hypertrophy, Right Ventricular - metabolism | Myocytes, Smooth Muscle - metabolism | Hypertrophy, Right Ventricular - genetics | Muscle, Smooth, Vascular - drug effects | Cell Proliferation - physiology | Cells, Cultured | Rats | Hypertension, Pulmonary - metabolism | Pulmonary Artery - drug effects | Rats, Sprague-Dawley | Down-Regulation - physiology | Poly(ADP-ribose) Polymerases - metabolism | Animals | Signal Transduction - drug effects | Lung - drug effects | Signal Transduction - physiology | Poly (ADP-Ribose) Polymerase-1 | Genotype & phenotype | Smooth muscle | Rodents | Apoptosis | Index Medicus
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5. Full Text Dysregulated Renin-Angiotensin-Aldosterone System Contributes to Pulmonary Arterial Hypertension
by de Man, F.S and Tu, L and Handoko, M.L and Rain, S and Ruiter, G and Francois, C and Schalij, I and Dorfmuller, P and Simonneau, G and Fadel, E and Perros, F and Boonstra, A and Postmus, P.E and van der Velden, J and Vonk Noordegraaf, A and Humbert, M and Eddahibi, S and Guignabert, C
American journal of respiratory and critical care medicine, ISSN 1073-449X, 2012, Volume 186, Issue 8, pp. 780 - 789
Idiopathic pulmonary arterial hypertension | Renin angiotensin system | Smooth muscle cells | Monocrotaline | Endothelial cells | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | Intensive care medicine | Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Pneumology | Up-Regulation | Humans | Middle Aged | Cells, Cultured | Losartan - pharmacology | Proportional Hazards Models | Hypertension, Pulmonary - physiopathology | Rats | Familial Primary Pulmonary Hypertension | Male | Angiotensin II Type 1 Receptor Blockers - pharmacology | Case-Control Studies | Disease Progression | Animals | Myocytes, Smooth Muscle | Receptor, Angiotensin, Type 1 - metabolism | Female | Renin-Angiotensin System - drug effects | Hypertension, Pulmonary - drug therapy | Endothelium, Vascular | Index Medicus | Abridged Index Medicus | Receptor, Angiotensin, Type 1 | endothelial cells | monocrotaline | Hypertension, Pulmonary | renin angiotensin system | idiopathic pulmonary arterial hypertension | smooth muscle cells | Angiotensin II Type 1 Receptor Blockers | Renin-Angiotensin System | Losartan
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6. Full Text BET Bromodomain Inhibitors and Pulmonary Arterial Hypertension: Take Care of the Heart
by Piquereau, Jerome and Perros, Frederic
American journal of respiratory and critical care medicine, ISSN 1073-449X, 11/2019, Volume 200, Issue 9, pp. 1187 - 1188
Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Heart | Antineoplastic Agents | Transcription Factors | Humans | Pulmonary Arterial Hypertension | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology | Cardiology and cardiovascular system
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7. Full Text Tertiary lymphoid organs in infection and autoimmunity
by Neyt, Katrijn and Perros, Frédéric and GeurtsvanKessel, Corine H and Hammad, Hamida and Lambrecht, Bart N
Trends in immunology, ISSN 1471-4906, 2012, Volume 33, Issue 6, pp. 297 - 305
Allergy and Immunology | Life Sciences & Biomedicine | Immunology | Science & Technology | Autoimmunity | Models, Immunological | Animals | Humans | Autoimmune Diseases - immunology | Infections - immunology | Lymphoid Tissue - immunology | Dendritic cells | T cells | Health aspects | Disease | Lymphocytes | Rodents | Ligands | Grants | Autoimmune diseases | Vascular endothelial growth factor | Chemokines | Immune system | Cell adhesion & migration | Index Medicus
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8. Full Text Translating research into improved patient care in pulmonary arterial hypertension
by Bonnet, Sébastien and Provencher, Steeve and Guignabert, Christophe and Perros, Frédéric and Boucherat, Olivier and Schermuly, Ralph Theo and Hassoun, Paul M and Rabinovitch, Marlene and Nicolls, Mark R and Humbert, Marc
American journal of respiratory and critical care medicine, ISSN 1073-449X, 03/2017, Volume 195, Issue 5, pp. 583 - 595
Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Biomedical Research | Disease Management | Patient Care - standards | Quality Improvement | Humans | Hypertension, Pulmonary - therapy | Index Medicus | Abridged Index Medicus | Pulmonary
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9. β-blockers in pulmonary arterial hypertension: Generation might matter
by Malenfant, Simon and Perros, Frédéric
The European respiratory journal, ISSN 0903-1936, 02/2016, Volume 47, Issue 2, pp. 682 - 684
Life Sciences & Biomedicine | Respiratory System | Science & Technology | Hypertension, Pulmonary - mortality | Humans | Adrenergic beta-Antagonists - adverse effects | Female | Male | Hypertension, Pulmonary - drug therapy | Cause of Death | Adrenergic beta-Antagonists - therapeutic use
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