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Journal Article
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 12/2017, Volume 232, Issue 12, pp. 3735 - 3743
Endometrial cancer is often characterized by PI3K/AKT pathway deregulation. Recently it has been suggested that SGK1, a serine/threonine protein kinase that... 
endometrial cancer | SGK1 | endoplasmic reticulum stress | ACTIVATION | PHYSIOLOGY | SERUM | AKT | CELL BIOLOGY | OVEREXPRESSION | KINASE SGK1 | PROTEIN GRP78 | PROSTATE-CANCER | RESISTANCE | UP-REGULATION | CARCINOMA | Transcription Factor CHOP - genetics | Caspase 9 - metabolism | Apoptosis - drug effects | Microtubule-Associated Proteins - metabolism | Humans | Middle Aged | Autophagy - drug effects | Case-Control Studies | Dose-Response Relationship, Drug | Heat-Shock Proteins - genetics | Immediate-Early Proteins - metabolism | Endometrial Neoplasms - genetics | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Female | Antineoplastic Agents - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Pyrazoles - pharmacology | Cell Survival - drug effects | Endometrial Neoplasms - enzymology | Endoplasmic Reticulum Stress - drug effects | Heat-Shock Proteins - metabolism | Pyrimidines - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | Signal Transduction - drug effects | Cell Line, Tumor | Endometrial Neoplasms - drug therapy | Endometrial Neoplasms - pathology | Protein Kinase Inhibitors - pharmacology | Beclin-1 - metabolism | Transcription Factor CHOP - metabolism | Immediate-Early Proteins - antagonists & inhibitors | Endometrial cancer | Analysis | Cancer cells | Cancer | Apoptosis | Intervention | Deregulation | AKT protein | Kinases | Tissues | Autophagy | Endometrium | Stresses | Threonine | Markers | Caspase | Poly(ADP-ribose) polymerase | Stress | 1-Phosphatidylinositol 3-kinase | Polymerase chain reaction | Inhibitors | Protein kinase | Caspase-9 | Protein-serine/threonine kinase | Immunofluorescence | Endoplasmic reticulum | Viability | Phagocytosis | Tumors | Structure-function relationships | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2018, Volume 24, Issue 4, pp. 450 - 462
Journal Article
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 04/2015, Volume 35, Issue 5, pp. 2006 - 2018
Background/Aims: Published observations on serum and glucocorticoid regulated kinase 1 (Sgk1) knockout murine models and Sgk1-specific RNA silencing in the RKO... 
Original Paper | Small molecule | SGK1 | Kinase inhibitor | Apoptosis | Cancer | Necrosis | ACTIVATION | PHYSIOLOGY | PROTEIN-KINASE | SERUM | AKT INHIBITOR | GLYCOSYLATION | CELL BIOLOGY | INSULIN-RECEPTOR | EPITHELIAL-CELLS | COLORECTAL-CANCER | EXPRESSION | Pyrazoles - therapeutic use | Paclitaxel - pharmacology | Apoptosis - drug effects | Colonic Neoplasms - drug therapy | Humans | Colonic Neoplasms - metabolism | Pyrimidines - chemistry | Immediate-Early Proteins - metabolism | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | MCF-7 Cells | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Phosphorylation - drug effects | Protein Stability | Antineoplastic Agents, Phytogenic - therapeutic use | Proto-Oncogene Proteins c-mdm2 - metabolism | Protein-Serine-Threonine Kinases - metabolism | Pyrazoles - pharmacology | Insulin - pharmacology | Tumor Suppressor Protein p53 - metabolism | Pyrimidines - pharmacology | Paclitaxel - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Colonic Neoplasms - pathology | Cell Line, Tumor | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Antineoplastic Agents, Phytogenic - pharmacology | G1 Phase Cell Cycle Checkpoints - drug effects | Immediate-Early Proteins - antagonists & inhibitors
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2011, Volume 108, Issue 12, pp. 4840 - 4845
Journal Article
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, ISSN 1756-9966, 05/2019, Volume 38, Issue 1, pp. 202 - 13
BackgroundGlioblastoma multiforme (GBM), due to its location, aggressiveness, heterogeneity and infiltrative growth, is characterized by an exceptionally... 
TARGET | APOPTOSIS | ACTIVATION | Quinacrine | PHOSPHORYLATION | RPPA | SERUM | CHLOROQUINE | Glioblastoma multiforme | Autophagy | SI113 | ADJUVANT | ONCOLOGY | PATHWAY | RESISTANCE | SGK1 | Autophagy (Cytology) | Usage | Cellular signal transduction | Genetic aspects | Research | Drug therapy | Radiotherapy | Signal transduction | Brain cancer | Stem cells | Cell cycle | Cytotoxicity | Radiation therapy | Kinases | Cancer therapies | Tumors | Apoptosis
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 10/2017, Volume 43, Issue 1, pp. 108 - 119
Background/Aims: The importance of copper in the metabolism of cancer cells has been widely studied in the last 20 years and a clear-cut association between... 
Medical research | Phosphorylation | Brain cancer | Radioisotopes | Radiation therapy | Metabolism | Kinases | Cancer therapies | Autophagy | Cell growth | Medical prognosis | Penicillin | Dosimetry | Tumors | Apoptosis
Journal Article
Translational Oncology, ISSN 1936-5233, 08/2019, Volume 12, Issue 8, pp. 1045 - 1055
Ovarian cancer is the second most common gynecological malignancy worldwide. Paclitaxel is particularly important in the therapy of ovarian carcinomas, but the... 
ACTIVATION | GENE | ONCOLOGY | PHOSPHORYLATION | KINASE 1 SGK1 | DOWN-REGULATION | ALPHA | SERUM | 2-DIMENSIONAL GEL-ELECTROPHORESIS | PROTEIN IDENTIFICATION | PROTEOMICS
Journal Article
Transfusion, ISSN 0041-1132, 01/2017, Volume 57, Issue 1, pp. 178 - 186
Journal Article