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Nature, ISSN 0028-0836, 09/2010, Volume 467, Issue 7314, pp. 430 - 435
Journal Article
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7339, pp. 518 - 522
Melanoma is a tumour of transformed melanocytes, which are originally derived from the embryonic neural crest. It is unknown to what extent the programs that... 
CELLS | ZEBRAFISH | GENE | MULTIDISCIPLINARY SCIENCES | KINASE | CARBAMOYL-PHOSPHATE SYNTHETASE | INHIBITOR | LEFLUNOMIDE | EXPRESSION | DISCOVERY | Transcription, Genetic - drug effects | Humans | Neural Crest - pathology | Gene Expression Regulation, Neoplastic | Melanoma - enzymology | Stem Cells - cytology | Zebrafish - embryology | Cell Lineage - drug effects | Oxidoreductases Acting on CH-CH Group Donors - antagonists & inhibitors | Neural Crest - metabolism | Melanoma - genetics | Neural Crest - enzymology | Proto-Oncogene Proteins B-raf - metabolism | Disease Models, Animal | Proto-Oncogene Proteins B-raf - chemistry | Animals, Genetically Modified | Rats | Genes, p53 - genetics | Melanoma - pathology | Zebrafish - genetics | Neural Crest - drug effects | Isoxazoles - pharmacology | Oxidoreductases Acting on CH-CH Group Donors - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Transcription, Genetic - physiology | Animals | Cell Differentiation - drug effects | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Stem Cells - drug effects | Stem Cells - pathology | Mice | Isoxazoles - therapeutic use | Amino Acid Substitution | Care and treatment | Gene mutations | Melanoma | Physiological aspects | Genetic aspects | Research | Tumor proteins | Health aspects | Risk factors | Mutation | Gene expression | Chemicals | Stem cells | Tumors
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2012, Volume 109, Issue 2, p. 535
Aire is a transcriptional regulator that induces expression of peripheral tissue antigens (PTA) in thymic medullary epithelial cells (MECs), driving... 
Tissue | Antigens | Immunology | RNA polymerase | Gene expression | Cells
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2018, Volume 115, Issue 9, p. 2144
Developmental transitions are guided by master regulatory transcription factors. During adipogenesis, a transcriptional cascade culminates in the expression of... 
Studies | Proteins | Chromatin | Transcription factors | Enhancers | Fibroblasts | Regulatory sequences | Peroxisome proliferator-activated receptors