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PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, pp. e20351 - e20351
Background: Squamous cell lung carcinomas account for approximately 25% of new lung carcinoma cases and 40,000 deaths per year in the United States. Although... 
MULTIPLE-MYELOMA | GEFITINIB | GENE | TRASTUZUMAB | MULTIDISCIPLINARY SCIENCES | THERAPEUTIC TARGET | RESISTANCE | CARCINOMAS | RECEPTOR | OVARIAN-CANCER | ACTIVATING MUTATIONS | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Cell Survival - drug effects | Lung Neoplasms - enzymology | Carcinoma, Non-Small-Cell Lung - genetics | Humans | Genetic Loci - genetics | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | 3' Untranslated Regions - genetics | Lung Neoplasms - pathology | Open Reading Frames - genetics | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Gene Knockdown Techniques | Gene Amplification - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - enzymology | RNA, Small Interfering - metabolism | Care and treatment | Analysis | Oncology, Experimental | Lung cancer, Small cell | Research | Lung cancer, Non-small cell | Health aspects | Cancer | Adenocarcinoma | Lung cancer | Oncology | Single-nucleotide polymorphism | Kinases | Medical schools | Clinical outcomes | Ovarian cancer | Rodents | Fibroblasts | Fibroblast growth factor receptor 1 | Growth factors | Squamous cell carcinoma | Small cell lung carcinoma | Non-small cell lung carcinoma | Lung carcinoma | Bladder cancer | Patients | Esophagus | Amplification | Chromosome 8 | Mutation | Fibroblast growth factor receptors | Tumors | Index Medicus
Journal Article
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2009, Volume 15, Issue 24, pp. 7502 - 7509
Gefitinib and erlotinib are ATP competitive inhibitors of the epidermal growth factor receptor (EGFR) tyrosine kinase and are approved around the world for the... 
GENE-MUTATIONS | KRAS MUTATIONS | CHEMOTHERAPY-NAIVE PATIENTS | ONCOLOGY | PROSPECTIVE PHASE-II | ACQUIRED-RESISTANCE | T790M MUTATION | EGFR MUTATIONS | GEFITINIB THERAPY | PROLONGED SURVIVAL | PREVIOUSLY TREATED PATIENTS
Journal Article
Nature, ISSN 0028-0836, 04/2015, Volume 520, Issue 7546, pp. 239 - 242
Non-small-cell lung cancer is the leading cause of cancer-related death worldwide(1). Chemotherapies such as the topoisomerase II (TopoII) inhibitor etoposide... 
SURVIVAL | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | COMPLEXES | SWI/SNF | GENE-EXPRESSION PROFILES | MUTATIONS | DRUG-COMBINATION | POLYCOMB | MICROARRAY DATA | CANCER CELL-LINES | Polycomb Repressive Complex 2 - antagonists & inhibitors | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Humans | Lung Neoplasms - pathology | Molecular Targeted Therapy | Antineoplastic Agents, Phytogenic - therapeutic use | Nuclear Proteins - genetics | DNA Helicases - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung Neoplasms - enzymology | Carcinoma, Non-Small-Cell Lung - genetics | Genes, erbB-1 - genetics | Etoposide - pharmacology | Etoposide - therapeutic use | Topoisomerase II Inhibitors - pharmacology | Transcription Factors - genetics | Anaphase - drug effects | Enhancer of Zeste Homolog 2 Protein | Topoisomerase II Inhibitors - therapeutic use | Xenograft Model Antitumor Assays | Animals | Cell Line, Tumor | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Antineoplastic Agents, Phytogenic - pharmacology | Cell Cycle - drug effects | Protein research | Care and treatment | Oncology, Experimental | Genetic aspects | Research | Lung cancer, Non-small cell | Drug therapy | Gene expression | Cancer | Proteins | Genes | Lung cancer | Genetic engineering | Mutation | Kinases | Cancer therapies | Deoxyribonucleic acid--DNA | Tumors | Apoptosis | Index Medicus | Etoposide | Chemotherapy | EZH2 inhibition | BRG1 | EGFR
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 499, Issue 7457, pp. 214 - 218
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2013, Volume 19, Issue 11, pp. 1469 - 1472
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 539, Issue 7629, pp. 390 - 395
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 43, pp. 15544 - 15549
Journal Article