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1974, Occasional paper - Centre for Research in the Educational Sciences, University of Edinburgh ; no. 20, ISBN 9780904170191, [2], 20 leaves
Book
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 06/2014, Volume 189, Issue 11, pp. 1374 - 1382
Journal Article
1973, Occasional paper - University of Edinburgh, Centre for Research in the Educational Sciences ; 14, ISBN 0904170136, [1], ii, 42 leaves
Book
Organic & biomolecular chemistry, ISSN 1477-0520, 10/2015, Volume 13, Issue 37, pp. 9629 - 9636
The racemic tertiary cathinones N,N-dimethylcathinone (1), N,N-diethylcathinone (2) and 2-(1-pyrrolidinyl)-propiophenone (3) have been prepared in reasonable... 
Amines - chemistry | Models, Molecular | Molecular Conformation | Alkaloids - chemistry | Alkaloids - isolation & purification
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 07/2009, Volume 8, Issue 7, pp. 1725 - 1738
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2017, Volume 56, Issue 38, pp. 11409 - 11414
The conformation of the activation loop (T‐loop) of protein kinases underlies enzymatic activity and influences the binding of small‐molecule inhibitors. By... 
activation loop | kinases | drug design | Aurora A | single-molecule studies | Aurora A | DRUG | PHOSPHORYLATION | CHEMISTRY, MULTIDISCIPLINARY | PROTEIN-KINASES | STRUCTURAL BASIS | A KINASE | INHIBITOR | BINDING | C-SRC | CONFORMATIONAL SELECTION | INSIGHTS | Fluorescence spectroscopy | Enzymes | Drug discovery | Protein kinases | Analysis | Communications | Communication
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, p. e28568
Human cancers often contain genetic alterations that disable G1/S checkpoint control and loss of this checkpoint is thought to critically contribute to cancer... 
MULTIPLE-MYELOMA | BREAST-CANCER | TRANSLATIONAL REGULATION | UNFOLDED-PROTEIN RESPONSE | RETINOBLASTOMA PROTEIN | CYCLIN D1 | PHOSPHORYLATION | ER STRESS | MULTIDISCIPLINARY SCIENCES | ENDOPLASMIC-RETICULUM | CELL-CYCLE | Enzyme Activators - pharmacology | Cyclin D1 - metabolism | Paclitaxel - pharmacology | Endoplasmic Reticulum Stress - drug effects | Oligonucleotide Array Sequence Analysis | eIF-2 Kinase - metabolism | Humans | Retinoblastoma Protein - metabolism | DNA, Complementary - genetics | Transcriptome - drug effects | Transcriptome - genetics | Enzyme Activation - drug effects | Mice, Knockout | Animals | Drug Interactions | Signal Transduction - drug effects | Enzyme Activators - chemistry | Eukaryotic Initiation Factor-2 - metabolism | Mice | Phosphorylation - drug effects | Drug Evaluation, Preclinical | G1 Phase Cell Cycle Checkpoints - drug effects | S Phase Cell Cycle Checkpoints - drug effects | Cluster Analysis | Chemotherapy | Genetic aspects | Genetic translation | Phosphotransferases | Cancer | Ubiquitin | Phosphorylation | Biomedical research | Transcription | Laboratories | Genes | Multiple myeloma | Activation | Identification | Biology | Sleep apnea | Taxane | Kinases | Phosphatase | Anticancer properties | Proteins | Signal transduction | Paclitaxel | Cell cycle | Genetics | Initiation factor eIF-2 | Deoxyribonucleic acid--DNA | Medical research | Translation | Cyclin-dependent kinases | Translation initiation | Translation initiation factor 2 | Mode of action | Signaling | DNA microarrays | Mutation | Taxanes | Endoplasmic reticulum | Apoptosis | Deoxyribonucleic acid | DNA
Journal Article
Frontiers in Neurology, ISSN 1664-2295, 2015, Volume 6, Issue MAY, p. 105
Hyperacusis is a frequent auditory disorder where sounds of normal volume are perceived as too loud or even painfully loud. There is a high degree of... 
Hyperacusis | Tinnitus | Loudness discomfort levels | Audiogram | Hearing loss | hyperacusis | NOISE | MECHANISMS | tmnitus | audiogram | NEUROSCIENCES | CLINICAL NEUROLOGY | TINNITUS | loudness discomfort levels | NORMAL-HEARING SENSITIVITY | INDUCED COCHLEAR NEUROPATHY | SOUND | hearing loss | AUDITORY-SENSITIVITY | LOUDNESS | HYPERSENSITIVITY | PLASTICITY | Hearing Loss
Journal Article
Synlett, ISSN 0936-5214, 2001, Volume 2001, Issue 9, pp. 1423 - 1427
An efficient synthesis of a 1,4-benzodiazepine was accomplished using copper catalysed amination of an arylbromide with the soluble bis-tetrabutylammonium salt... 
letter | SB-214857 | Amino acids | Aromatic amination | Copper catalysis | Benzodiazepines | copper catalysis | benzodiazepines | amino acids | ARYL HALIDES | SURFACE | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | aromatic amination
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2013, Volume 56, Issue 24, pp. 10045 - 10065
Journal Article
Angewandte Chemie, ISSN 1433-7851, 09/2017, Volume 56, Issue 38, p. 11409
The conformation of the activation loop (T-loop) of protein kinases underlies enzymatic activity and influences the binding of small-molecule inhibitors. By... 
Fluorescence spectroscopy | Spectroscopy | Inhibitors | Rate constants | Enzymatic activity | Spectrum analysis | Fluorescence | Activation | Kinases | Equilibrium
Journal Article
1997, ISBN 9781855673861, xiii, 178
Book
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2012, Volume 55, Issue 20, pp. 8721 - 8734
Journal Article
Synlett, ISSN 0936-5214, 2/2006, Volume 2006, Issue 3, pp. 0460 - 0462
Abstract Treatment of N,N-diformylaminomethyl aryl ketones with phosphorus pentasulfide/triethylamine in chloroform gives 5-arylthiazoles directly in good... 
letter | Heterocycles | 1,3-thiazole | Phosphorus pentasulfide | Lithiation | FUNCTIONALIZATION | POTENT | heterocycles | SUBSTITUTED THIAZOLES | CHEMISTRY, ORGANIC | lithiation | INHIBITORS | phosphorus pentasulfide | CATALYZED ARYLATION
Journal Article