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SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 6281 - 10
Compounds that are candidates for drug repurposing can be ranked by leveraging knowledge available in the biomedical literature and databases. This knowledge,... 
PROLIFERATION | POLYCYSTIC KIDNEY-DISEASE | MULTIDISCIPLINARY SCIENCES | GROWTH | Databases | Disease | Polycystic kidney | Semantics | Clinical trials | Kidney diseases | Knowledge | Vasopressin
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 806 - 9
Capillary electrophoresis-mass spectrometry (CE-MS) using a sheathless porous tip interface emerged as an attractive tool in metabolomics thanks to its... 
ELECTROPHORESIS-MASS-SPECTROMETRY | SPRAYER | SIGNALING PATHWAYS | INTERFACE | MULTIDISCIPLINARY SCIENCES | SENSITIVITY | CAPILLARY-ELECTROPHORESIS | MECHANISMS | ESI | Creatinine | Metabolomics | Kidneys | Polycystic kidney | Capillary electrophoresis | Mass spectroscopy | Biomass | Metabolism | Creatine | Carnitine | Metabolites | Betaine | Kidney diseases | Glutamine
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 04/2018, Volume 233, Issue 4, pp. 3615 - 3628
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 04/2019, Volume 33, Issue 4, pp. 5034 - 5044
Magnesium (Mg2+) is an important cofactor of many enzymes crucial for life; therefore, maintaining a Mg2+ balance in the body is essential. In the kidney, the... 
primary cilia | BIOCHEMISTRY & MOLECULAR BIOLOGY | FUNCTIONAL-CHARACTERIZATION | ion channels | CELL BIOLOGY | COLLECTING DUCT | MATHEMATICAL-MODEL | DCT | CHANNEL | FUROSEMIDE | SHEAR-STRESS | BIOLOGY | mechanosensation | TRPM6 | REABSORPTION | EXPRESSION | fluid shear stress
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 09/2018, Volume 315, Issue 3, pp. F537 - F546
The PKD1 gene encodes polycystin-1 (PC1), a mechanosensor triggering intracellular responses upon urinary flow sensing in kidney tubular cells. Mutations in... 
Precystic | ADPKD | Pkd1 | Electrolyte imbalance | PC1 | KIDNEY-DISEASE | PHYSIOLOGY | DETERMINANT | PARAMETERS | precystic | PRIMARY CILIUM | electrolyte imbalance | EPITHELIAL-CELLS | CALCIUM | UROLOGY & NEPHROLOGY | MICE | HYPERTENSION | PROTEINS | THICK ASCENDING LIMB | Water | Physiological aspects | Electrolytes | Models | Membrane proteins | Polycystic kidney disease
Journal Article
Nephrology Dialysis Transplantation, ISSN 0931-0509, 06/2019, Volume 34, Issue Supplement_1
Journal Article
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, ISSN 0931-0509, 04/2019
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive cyst formation, leading to growth in kidney volume and renal function... 
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 1931-857X, 04/2017, Volume 312, Issue 4, pp. F577 - F577
Autosomal dominant polycystic kidney disease (ADPKD) is the fourth most common cause of end-stage renal disease. The disease course can be highly variable and... 
Journal Article
Journal of molecular cell biology, ISSN 1759-4685, 05/2019
Polycystic kidney disease (PKD) is a prevalent genetic disorder, characterized by the formation of kidney cysts that progressively lead to kidney failure. The... 
Journal Article
Journal Article
EBIOMEDICINE, ISSN 2352-3964, 09/2019, Volume 47, pp. 436 - 445
Background: Multiple preclinical studies have highlighted AMP-activated protein kinase (AMPK) as a potential therapeutic target for autosomal dominant... 
OXIDATION | PATHWAYS | DRUG | MEDICINE, RESEARCH & EXPERIMENTAL | TOLVAPTAN | MECHANISMS | INHIBITION | Canagliflozin | AMPK | Salsalate | Metformin | ACTIVATES AMPK | Polycystic kidney disease | SIROLIMUS
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2015, Volume 125, Issue 6, pp. 2399 - 2399
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by renal cyst formation, inflammation, and fibrosis. Macrophages infiltrate cystic... 
Journal Article
Journal Article