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American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, ISSN 0363-6119, 02/2009, Volume 296, Issue 2, pp. 208 - 216
The adaptive immune response and, in particular, T cells have been shown to be important in the genesis of hypertension. In the present study, we sought to... 
Superoxide | Cytokines | TNF-α | Electron spin resonance | NADPH oxidase | Adoptive transfer | RHEUMATOID-ARTHRITIS | PHYSIOLOGY | TNF-alpha | VASCULAR DYSFUNCTION | adoptive transfer | FACTOR-KAPPA-B | MECHANISMS | FACTOR-ALPHA | electron spin resonance | TUMOR-NECROSIS-FACTOR | AT RECEPTORS | cytokines | superoxide | CORONARY-ARTERY-DISEASE | CONVERTING-ENZYME | Blood Pressure | Catalase - pharmacology | Renin - metabolism | Tumor Necrosis Factor-alpha - metabolism | Angiotensin II - administration & dosage | Homeodomain Proteins - metabolism | Adoptive Transfer | Angiotensin II Type 1 Receptor Blockers - pharmacology | T-Lymphocytes - transplantation | NADPH Oxidases - deficiency | T-Lymphocytes - metabolism | Time Factors | T-Lymphocytes - drug effects | Peptidyl-Dipeptidase A - metabolism | Superoxides - metabolism | NADPH Oxidases - genetics | Polyethylene Glycols - pharmacology | Autocrine Communication | Receptor, Angiotensin, Type 2 - genetics | Infusion Pumps, Implantable | Superoxide Dismutase - pharmacology | Angiotensin II - metabolism | Mice, Inbred C57BL | Cells, Cultured | Losartan - pharmacology | Angiotensinogen - metabolism | Imidazoles - pharmacology | Homeodomain Proteins - genetics | Mice, Knockout | Animals | Lymphocyte Activation - drug effects | Receptor, Angiotensin, Type 1 - metabolism | Angiotensin II Type 2 Receptor Blockers | Renin-Angiotensin System - drug effects | T-Lymphocytes - immunology | Mice | Pyridines - pharmacology | Receptor, Angiotensin, Type 2 - deficiency | Call for Papers
Journal Article
Journal Article
Hypertension, ISSN 0194-911X, 09/2005, Volume 46, Issue 3, pp. 569 - 576
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 08/2007, Volume 293, Issue 2, pp. 1242 - 1253
Rats harboring the human renin and angiotensinogen genes (dTGR) feature angiotensin (ANG) II/hypertension-induced cardiac damage and die suddenly between wk 7... 
Magnetocardiography | Noninvasive mapping | Double-transgenic rat model | In vivo electrophysiological study | CURRENT DOWN-REGULATION | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | noninvasive mapping | HEART-FAILURE | CARDIAC-ARRHYTHMIA | TRANSGENIC RATS | QRS COMPLEX | in vivo electrophysiological study | DILATED CARDIOMYOPATHY | double-transgenic rat model | magnetocardiography | ATRIAL-FIBRILLATION | MYOCARDIAL FIBROSIS | HUMAN RENIN | MOUSE MODEL | PERIPHERAL VASCULAR DISEASE | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Cardiomegaly - pathology | Death, Sudden, Cardiac - prevention & control | Hypertension - drug therapy | Male | RNA, Messenger - metabolism | Angiotensin II Type 1 Receptor Blockers - pharmacology | Renin - genetics | Shal Potassium Channels - genetics | Time Factors | Myocardium - metabolism | Tachycardia, Ventricular - metabolism | Electrocardiography | Disease Models, Animal | Heart Conduction System - metabolism | Tachycardia, Ventricular - complications | Connexin 43 - metabolism | Losartan - pharmacology | Tachycardia, Ventricular - etiology | Cardiomegaly - physiopathology | Rats | Angiotensinogen - metabolism | Cardiac Pacing, Artificial | Tachycardia, Ventricular - prevention & control | Hypertension - pathology | Hypertension - metabolism | Shal Potassium Channels - metabolism | Cardiomegaly - prevention & control | Heart Conduction System - physiopathology | Rats, Sprague-Dawley - genetics | Cardiomegaly - metabolism | Blood Pressure | Renin - metabolism | Cardiomegaly - etiology | Death, Sudden, Cardiac - etiology | Connexin 43 - genetics | Angiotensin II - metabolism | Animals, Genetically Modified | Myocardium - pathology | Heart Conduction System - drug effects | Telemetry | Cardiomegaly - complications | Hypertension - physiopathology | Angiotensinogen - genetics | Tachycardia, Ventricular - physiopathology | Animals | Losartan - therapeutic use | Hypertension - complications | Ventricular Remodeling - drug effects
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 05/2008, Volume 117, Issue 20, pp. 2645 - 2656
Journal Article
Journal Article
Journal of the Renin-Angiotensin-Aldosterone System, ISSN 1470-3203, 06/2007, Volume 8, Issue 2, pp. 81 - 84
We studied the effects of extremely low-dose human renin inhibition (aliskiren) with low angiotensin II receptor blockade (losartan) in a novel... 
Renin inhibitor | Inflammation | Albuminuria | Angiotensin II | Cardiac damage
Journal Article
American Journal of Physiology, ISSN 0363-6119, 02/2009, Volume 296, Issue 2, p. R208
  The adaptive immune response and, in particular, T cells have been shown to be important in the genesis of hypertension. In the present study, we sought to... 
Hypertension | Enzymes | Peptides | Cytokines | Physiology | Gene expression | Cells
Journal Article
Hypertension, ISSN 0194-911X, 03/2009, Volume 53, Issue 3, pp. 516 - 523
Renin initiates angiotensin II formation and has no other known functions. We observed that transgenic rats (TGR) overexpressing the human renin gene (hREN)... 
Journal Article
Circulation, ISSN 0009-7322, 05/2008, Volume 117, Issue 20, pp. 2645 - 2656
BACKGROUND: Angiotensin (Ang) II-induced target-organ damage involves innate and acquired immunity. Mice deficient for the helix-loop-helix transcription... 
Journal Article
Circulation Research, ISSN 0009-7330, 09/2005, Volume 97, Issue 7, pp. 716 - 724
We tested whether or not complement activation participates in angiotensin (Ang) II-induced vasculopathy. We used double transgenic rats harboring human renin... 
Journal Article
Journal Article
The American Journal of Physiology, ISSN 0002-9513, 02/2009, Volume 296, Issue 2, p. R208
The adaptive immune response and, in particular, T cells have been shown to be important in the genesis of hypertension. In the present study, we sought to... 
Immune response | Cellular control mechanisms | Angiotensin | Influence | Superoxide | Research | T cells | Properties
Journal Article
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