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The Plant Journal, ISSN 0960-7412, 05/2012, Volume 70, Issue 3, pp. 460 - 470
Coumarins are important compounds that contribute to the adaptation of plants to biotic or abiotic stresses. Among coumarins, umbelliferone occupies a pivotal... 
Ruta graveolens | furanocoumarin | umbelliferone | coumarin | scopoletin | 2‐oxoglutarate‐dependent dioxygenase | 2-oxoglutarate-dependent dioxygenase | Coumarins - metabolism | Dioxygenases - metabolism | Dioxygenases - isolation & purification | Gene Expression - genetics | Molecular Sequence Data | Plant Roots - genetics | Phylogeny | RNA, Plant - metabolism | Umbelliferones - biosynthesis | Plant Stems - genetics | Coumarins - isolation & purification | Umbelliferones - metabolism | Ruta - genetics | Umbelliferones - analysis | Plant Proteins - antagonists & inhibitors | Conserved Sequence | Plant Proteins - metabolism | Plant Stems - chemistry | Plant Leaves - enzymology | Transgenes | Scopoletin - metabolism | Plant Leaves - chemistry | Plant Proteins - isolation & purification | Amino Acid Sequence | Ruta - chemistry | Escherichia coli - enzymology | Furocoumarins - metabolism | Furocoumarins - pharmacology | Ruta - enzymology | Plant Stems - enzymology | Plant Proteins - genetics | Coumarins - analysis | Dioxygenases - antagonists & inhibitors | Sequence Alignment | Dioxygenases - genetics | Plant Leaves - genetics | Escherichia coli - genetics | Tobacco - genetics | Plant Roots - chemistry | Plant Roots - enzymology | Scopoletin - analysis | Tobacco - enzymology | Amino Acid Substitution | Arabidopsis thaliana | Enzymes | Escherichia coli | Genes | Coumarins | Exhibitions | Universities and colleges | Plant biology | Biochemistry | Biosynthesis | Gene expression | Index Medicus | Life Sciences
Journal Article
JOURNAL OF CROHNS & COLITIS, ISSN 1873-9946, 04/2016, Volume 10, Issue 4, pp. 495 - 500
Crohn's disease [CD] is a chronic progressive and destructive condition. Half of all CD patients will develop bowel damage at 10 years. As in rheumatic... 
Journal Article
by Jostins, Luke and Ripke, Stephan and Weersma, Rinse K and Duerr, Richard H and McGovern, Dermot P and Hui, Ken Y and Lee, James C and Schumm, L. Philip and Sharma, Yashoda and Anderson, Carl A and Essers, Jonah and Mitrovic, Mitja and Ning, Kaida and Cleynen, Isabelle and Theatre, Emilie and Spain, Sarah L and Raychaudhuri, Soumya and Goyette, Philippe and Wei, Zhi and Abraham, Clara and Achkar, Jean-Paul and Ahmad, Tariq and Amininejad, Leila and Ananthakrishnan, Ashwin N and Andersen, Vibeke and Anews, Jane M and Baidoo, Leonard and Balschun, Tobias and Bampton, Peter A and Bitton, Alain and Boucher, Gabrielle and Brand, Stephan and Büning, Carsten and Cohain, Ariella and Cichon, Sven and D'Amato, Mauro and de Jong, Dirk and Devaney, Kathy L and Dubinsky, Marla and Edwards, Cathryn and Ellinghaus, David and Ferguson, Lynnette R and Franchimont, Denis and Fransen, Karin and Gearry, Richard and Georges, Michel and Gieger, Christian and Glas, Jürgen and Haritunians, Talin and Hart, Ailsa and Hawkey, Chris and Hedl, Matija and Hu, Xinli and Karlsen, Tom H and Kupcinskas, Limas and Kugathasan, Subra and Latiano, Anna and Laukens, Debby and Lawrance, Ian C and Lees, Charlie W and Louis, Edouard and Mahy, Gillian and Mansfield, John and Morgan, Angharad R and Mowat, Craig and Newman, William and Palmieri, Orazio and Ponsioen, Cyriel Y and Potocnik, Uros and Prescott, Natalie J and Regueiro, Miguel and Rotter, Jerome I and Russell, Richard K and Sanderson, Jeremy D and Sans, Miquel and Satsangi, Jack and Schreiber, Stefan and Simms, Lisa A and Sventoraityte, Jurgita and Targan, Stephan R and Taylor, Kent D and Tremelling, Mark and Verspaget, Hein W and de Vos, Martine and Wijmenga, Cisca and Wilson, David C and Winkelmann, Juliane and Xavier, Ramnik J and Zeissig, Sebastian and Zhang, Bin and Zhang, Clarence K and Zhao, Hongyu and Silverberg, Mark S and Annese, Vito and Hakonarson, Hakon and Brant, Steven R and Radford-Smith, Graham and Mathew, Christopher G and Rioux, John D and Schadt, Eric E and ... and Int IBD Genetics Consortium IIBDGC and International IBD Genetics Consortium (IIBDGC) and The International IBD Genetics Consortium (IIBDGC) and Region Örebro län and Örebro universitet and Institutionen för medicinska vetenskaper
Nature, ISSN 0028-0836, 2012, Volume 491, Issue 7422, pp. 119 - 124
Crohn's disease and ulcerative colitis, the two common forms of inflammatory bowel disease (IBD), affect over 2.5 million people of European ancestry, with... 
HYPER-IGE SYNDROME | RISK LOCI | NETWORK | NUMBER | METAANALYSIS | TUBERCULOSIS | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | MUTATIONS | EXPRESSION | Crohn Disease - genetics | Humans | Inflammatory Bowel Diseases - immunology | Colitis, Ulcerative - genetics | Mycobacterium tuberculosis - immunology | Inflammatory Bowel Diseases - physiopathology | Colitis, Ulcerative - immunology | Host-Pathogen Interactions - immunology | Mycobacterium tuberculosis - pathogenicity | Haplotypes - genetics | Mycobacterium - pathogenicity | Mycobacterium Infections - genetics | Inflammatory Bowel Diseases - genetics | Crohn Disease - microbiology | Mycobacterium Infections - microbiology | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Reproducibility of Results | Mycobacterium - immunology | Crohn Disease - immunology | Genome, Human - genetics | Phenotype | Colitis, Ulcerative - microbiology | Host-Pathogen Interactions - genetics | Polymorphism, Single Nucleotide - genetics | Inflammatory Bowel Diseases - microbiology | Crohn Disease - physiopathology | Colitis, Ulcerative - physiopathology | Inflammatory bowel disease | Candidates | Tuberculosis | Architecture | Genetics | Genomes | Diabetes | Gene expression | Health risk assessment | Immune system | Index Medicus | Rheumatology and Autoimmunity | Basic Medicine | Medical Genetics | Medicinsk genetik | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Reumatologi och inflammation | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin
Journal Article
by Anderson, Carl A and Boucher, Gabrielle and Lees, Charlie W and Franke, Ane and D'Amato, Mauro and Taylor, Kent D and Lee, James C and Goyette, Philippe and Imielinski, Marcin and Latiano, Anna and Lagacé, Caroline and Scott, Regan and Amininejad, Leila and Bumpstead, Suzannah and Baidoo, Leonard and Baldassano, Robert N and Barclay, Murray and Bayless, Theodore M and Brand, Stephan and Büning, Carsten and Colombel, Jean-Frédéric and Denson, Lee A and de Vos, Martine and Dubinsky, Marla and Edwards, Cathryn and Ellinghaus, David and Fehrmann, Rudolf S. N and Floyd, James A. B and Florin, Timothy and Franchimont, Denis and Franke, Lude and Georges, Michel and Glas, Jürgen and Glazer, Nicole L and Guthery, Stephen L and Haritunians, Talin and Hayward, Nicholas K and Hugot, Jean-Pierre and Jobin, Gilles and Laukens, Debby and Lawrance, Ian and Lémann, Marc and Levine, Arie and Libioulle, Cecile and Louis, Edouard and McGovern, Dermot P and Milla, Monica and Montgomery, Grant W and Morley, Katherine I and Mowat, Craig and Ng, Aylwin and Newman, William and Ophoff, Roel A and Papi, Laura and Palmieri, Orazio and Peyrin-Biroulet, Laurent and Panés, Julián and Phillips, Anne and Prescott, Natalie J and Proctor, Deborah D and Roberts, Rebecca and Russell, Richard and Rutgeerts, Paul and Sanderson, Jeremy and Sans, Miquel and Schumm, Philip and Seibold, Frank and Sharma, Yashoda and Simms, Lisa A and Seielstad, Mark and Steinhart, A. Hillary and Targan, Stephan R and van den Berg, Leonard H and Vatn, Morten and Verspaget, Hein and Walters, Thomas and Wijmenga, Cisca and Wilson, David C and Westra, Harm-Jan and Xavier, Ramnik J and Zhao, Zhen Z and Ponsioen, Cyriel Y and Andersen, Vibeke and Torkvist, Leif and Gazouli, Maria and Anagnou, Nicholas P and Karlsen, Tom H and Kupcinskas, Limas and Sventoraityte, Jurgita and Mansfield, John C and Kugathasan, Subra and Silverberg, Mark S and Halfvarson, Jonas and Rotter, Jerome I and Mathew, Christopher G and Griffiths, Anne M and Gearry, Richard and Ahmad, Tariq and Brant, Steven R and Chamaillard, Mathias and ... and Hälsoakademin and Örebro universitet
Nature genetics, ISSN 1061-4036, 2011, Volume 43, Issue 3, pp. 246 - 252
Journal Article
by Feagan, Brian G and Sandborn, William J and Gasink, Christopher and Jacobstein, Douglas and Lang, Yinghua and Friedman, Joshua R and Blank, Marion A and Johanns, Jewel and Gao, Long-Long and Miao, Ye and Adedokun, Omoniyi J and Sands, Bruce E and Hanauer, Stephen B and Vermeire, Severine and Targan, Stephan and Ghosh, Subrata and De Villiers, Willem J and Colombel, Jean-Frederic and Tulassay, Zsolt and Seidler, Ursula and Salzberg, Bruce A and Desreumaux, Pierre and Lee, Scott D and Loftus, Edward V and Dieleman, Levinus A and Katz, Seymour and Rutgeerts, Paul and Bampton, P and Chung, A and Connor, S and Debinski, H and Leong, R and Macrae, F and Pavli, P and Sorrentino, D and van den Bogaerde, J and Vogel, W and Vogelsang, H and Louis, E and Mana, F and Zaltman, C and Aumais, G and Bernstein, C and Bressler, B and Dhalla, S and Marshall, J and Panaccione, R and Ropeleski, M and Stehlik, J and Volfova, M and Brynskov, J and Glerup, H and Abitbol-Selinger, V and Allez, M and Beaugerie, L and Bourreille, A and Cadiot, G and Dupas, J and Grimaud, J and Laharie, D and Lerebours, E and Moreau, J and Baumgart, D and Brand, S and Ebert, M and Ehehalt, R and Hasselblatt, P and Howaldt, S and Klaus, J and Krummenerl, P and Kucharzik, T and Lügering, A and Mudter, J and Preiss, J and Schreiber, S and Stallmach, A and Stein, J and Strauch, U and Salamon, A and Patchett, S and Lahat-Zok, A and Rachmilewitz, D and Annese, V and Bossa, F and Guidi, L and Kohn, A and Rocca, R and Ando, A and Ashida, T and Hanai, H and Ishida, T and Ito, H and Matsumoto, T and Motoya, S and Nakamura, S and Sameshima, Y and Suzuki, Y and Watanabe, K and Yamagami, H and Yamamoto, T and ... and UNITI-IM-UNITI Study Grp and UNITI–IM-UNITI Study Group
New England Journal of Medicine, ISSN 0028-4793, 11/2016, Volume 375, Issue 20, pp. 1946 - 1960
Journal Article
American Journal of Gastroenterology, ISSN 0002-9270, 02/2018, Volume 113, Issue 2, pp. 265 - 272
OBJECTIVES: Few data are available to describe the changes in incidence of pediatric-onset inflammatory bowel disease (IBD). The aim of this study was to... 
Journal Article
by Romagnoni, A and Jegou, S and Van Steen, K and Wainrib, G and Hugot, JP and Peyrin-Biroulet, L and Chamaillard, M and Colombel, JF and Cottone, M and D'Amato, M and D'Inca, R and Halfvarson, J and Henderson, P and Karban, A and Kennedy, NA and Khan, MA and Lemann, M and Levine, A and Massey, D and Milla, M and Ng, SME and Oikonomou, I and Peeters, H and Proctor, DD and Rahier, JF and Rutgeerts, P and Seibold, F and Stronati, L and Taylor, KM and Torkvist, L and Ublick, K and Van Limbergen, J and Van Gossum, A and Vatn, MH and Zhang, H and Zhang, W and Andrews, JM and Bampton, PA and Barclay, M and Florin, TH and Gearry, R and Krishnaprasad, K and Lawrance, IC and Mahy, G and Montgomery, GW and Radford-Smith, G and Roberts, RL and Simms, LA and Hanigan, K and Croft, A and Amininijad, L and Cleynen, I and Dewit, O and Franchimont, D and Georges, M and Laukens, D and Theatre, E and Vermeire, S and Aumais, G and Baidoo, L and Barrie, AM and Beck, K and Bernard, EJ and Binion, DG and Bitton, A and Brant, SR and Cho, JH and Cohen, A and Croitoru, K and Daly, MJ and Datta, LW and Deslandres, C and Duerr, RH and Dutridge, D and Ferguson, J and Fultz, J and Goyette, P and Greenberg, GR and Haritunians, T and Jobin, G and Katz, S and Lahaie, RG and McGovern, DP and Nelson, L and Ng, SM and Ning, K and Pare, P and Regueiro, MD and Rioux, JD and Ruggiero, E and Schumm, LP and Schwartz, M and Scott, R and Sharma, Y and Silverberg, MS and Spears, D and Steinhart, AH and Stempak, JM and Swoger, JM and Tsagarelis, C and ... and Int Inflammatory Bowel Dis Genetic and International Inflammatory Bowel Disease Genetics Consortium (IIBDGC)
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 1 - 18
Crohn Disease (CD) is a complex genetic disorder for which more than 140 genes have been identified using genome wide association studies (GWAS). However, the... 
LOCI | INFLAMMATORY-BOWEL-DISEASE | RISK PREDICTION | ASSOCIATION | MULTIDISCIPLINARY SCIENCES | Inflammatory bowel diseases | Complementarity | Epistasis | Genomes | Genetic variance | Learning algorithms | Genetic markers | Genotyping | Intestine | Neural networks | Machine learning | Quality control | Artificial intelligence | Genotypes
Journal Article
by Sacleux, S.‐C and Sarter, H and Fumery, M and Charpentier, C and Guillon‐Dellac, N and Coevoet, H and Pariente, B and Peyrin‐Biroulet, L and Gower‐Rousseau, C and Savoye, G and Andre, JM and Antonietti, M and Aouakli, A and Armand, A and Aroichane, I and Assi, F and Aubet, JP and Auxenfants, E and Ayafi‐Ramelot, F and Bankovski, D and Barbry, B and Bardoux, N and Baron, P and Baudet, A and Bazin, B and Bebahani, A and Becqwort, JP and Benet, V and Benali, H and Benguigui, C and Ben Soussan, E and Bental, A and Berkelmans, I and Bernet, J and Bernou, K and Bernou‐Dron, C and Bertot, P and Bertiaux‐Vandaële, N and Bertrand, V and Billoud, E and Biron, N and Bismuth, B and Bleuet, M and Blondel, F and Blondin, V and Bohon, P and Boniface, E and Bonnière, P and Bonvarlet, E and Bonvarlet, P and Boruchowicz, A and Bostvironnois, R and Boualit, M and Bouche, B and Boudaillez, C and Bourgeaux, C and Bourgeois, M and Bourguet, A and Bourienne, A and Branche, J and Bray, G and Brazier, F and Breban, P and Brihier, H and Brung‐Lefebvre, V and Bulois, P and Burgiere, P and Butel, J and Canva, JY and Canva‐Delcambre, V and Capron, JP and Cardot, F and Carpentier, P and Cartier, E and Cassar, JF and Cassagnou, M and Castex, JF and Catala, P and Cattan, S and Catteau, S and Caujolle, B and Cayron, G and Chandelier, C and Chantre, M and Charles, J and Charneau, T and Chavance‐Thelu, M and Chirita, D and Choteau, A and Claerbout, JF and Clergue, PY and Coevoet, H and Cohen, G and Collet, R and Colombel, JF and Coopman, S and Corvisart, J and Cortot, A and Couttenier, F and Crinquette, JF and ... and EPIMAD Grp and EPIMAD Group and the EPIMAD Group
Alimentary Pharmacology & Therapeutics, ISSN 0269-2813, 06/2018, Volume 47, Issue 12, pp. 1652 - 1660
Journal Article