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Biochemical Society Transactions, ISSN 0300-5127, 11/2018, Volume 46, Issue 6, pp. 1707 - 1712
Leucine-rich repeat kinase 2 (LRRK2) is mutated in familial Parkinson's disease, and pathogenic mutations activate the kinase activity. A tour de force screen... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEIN | KINASE
Journal Article
Cell, ISSN 0092-8674, 12/2013, Volume 155, Issue 6, pp. X1203 - 1206
The 2013 Nobel Prize in Physiology or Medicine has been awarded to James Rothman, Randy Schekman, and Thomas Südhof "for their discoveries of machinery... 
Journal Article
Current Opinion in Cell Biology, ISSN 0955-0674, 2013, Volume 25, Issue 4, pp. 414 - 419
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 05/2016, Volume 213, Issue 3, pp. 297 - 299
An unsolved mystery in cell biology is how unusually large secretory cargoes are exported from the endoplasmic reticulum. In this issue, Santos et al. (2016.... 
Animals | Endoplasmic Reticulum | Collagen | Lipoproteins, LDL | Proteolipids | Lipoproteins | Cell research | Secretion | Physiological aspects | Research | Blood lipoproteins | Endoplasmic reticulum
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 10/2019, p. jcb.201902184
LRRK2 kinase mutations cause familial Parkinson’s disease and increased phosphorylation of a subset of Rab GTPases. Rab29 recruits LRRK2 to the trans-Golgi and... 
Journal Article
FEBS Letters, ISSN 0014-5793, 2009, Volume 583, Issue 23, pp. 3811 - 3816
Journal Article
The EMBO Journal, ISSN 0261-4189, 01/2019, Volume 38, Issue 2
Journal Article
The EMBO journal, ISSN 0261-4189, 01/2019, Volume 38, Issue 2
Journal Article
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 10/2013, Volume 203, Issue 2, p. 233
  Cyclin E regulates the cell cycle transition from G1 to S phase and is degraded before entry into G2 phase. Here we show that RhoBTB3, a Golgi-associated,... 
Eukaryotes | Cell cycle | Adenosine triphosphatase
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 10/2013, Volume 203, Issue 2, pp. 233 - 233
Cyclin E regulates the cell cycle transition from G1 to S phase and is degraded before entry into G2 phase. Here we show that RhoBTB3, a Golgi-associated,... 
Adenosinetriphosphatase
Journal Article
eLife, ISSN 2050-084X, 10/2019, Volume 8
Mutations that activate LRRK2 protein kinase cause Parkinson’s disease. LRRK2 phosphorylates a subset of Rab GTPases within their Switch-II motif controlling... 
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 09/2016, Volume 113, Issue 36
Export of LDL-derived cholesterol from lysosomes requires the cooperation of the integral membrane protein Niemann-Pick C1 (NPC1) and a soluble protein,... 
Physiological aspects | Observations | Cholesterol metabolism | Membrane proteins
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 48, p. 14876
  Lysosomes are lined with a glycocalyx that protects the limiting membrane from the action of degradative enzymes. We tested the hypothesis that Niemann-Pick... 
Proteins | Rodents | Glycosylation | Low density lipoprotein | Cells | Cholesterol
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 02/2010, Volume 188, Issue 4, p. 451
In this issue, Duran et al. (2010. J. Cell Biol. doi: 10.1083/ jcb.200911154) and Manjithaya et al. (2010. J. Cell Biol. doi: 10.1083/jcb.200911149) use yeast... 
Physiological aspects | Exocytosis | Observations
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 02/2010, Volume 188, Issue 4, p. 451
  In this issue, Duran et al. (2010. J. Cell Biol. doi: 10.1083/jcb.200911154) and Manjithaya et al. (2010. J. Cell Biol. doi: 10.1083/jcb.200911149) use yeast... 
Proteins | Enzymes | Yeast | Genetics | Binding sites
Journal Article
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