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chemistry, organic (10) 10
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The Journal of Organic Chemistry, ISSN 0022-3263, 11/2001, Volume 66, Issue 23, pp. 7575 - 7587
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 09/1994, Volume 59, Issue 18, pp. 5192 - 5205
Modifications were introduced in the side chain of didemnin B to afford several analogs (1f-1j) for biological testing in order to identify the features... 
DEPSIPEPTIDE | OXIDATION | IMMUNOSUPPRESSIVE CYCLIC PEPTIDE | INVITRO | CHEMISTRY, ORGANIC | PHASE-II | NORDIDEMNIN | TUNICATE | DIMETHYLBORON BROMIDE | RACEMIZATION | CLEAVAGE | Synthesis | Peptides | Analysis | Structure-activity relationships (Biochemistry)
Journal Article
Tetrahedron, ISSN 0040-4020, 1999, Volume 55, Issue 2, pp. 313 - 334
Based on information from X-ray, NMR, and SAR data, the N, O-diMeTyr 5 unit of didemnin B was believed to be important for biological activity. To determine... 
DEPSIPEPTIDE | IMMUNOSUPPRESSIVE CYCLIC PEPTIDE | INHIBITION | INVIVO | DIDEMNIN-B | CHEMISTRY | CHEMISTRY, ORGANIC | ALDEHYDES | RING ANALOG
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 03/1996, Volume 61, Issue 5, pp. 1655 - 1664
The didemnin class of biologically active cyclodepsipeptides, isolated from a marine tunicate, has shown antitumor, antiviral, and immunosuppressive... 
SODIUM TRIACETOXYBOROHYDRIDE | DIELS-ALDER REACTIONS | ENANTIOSELECTIVE SYNTHESIS | SECONDARY | CHEMISTRY, ORGANIC | COUPLING REAGENTS | DIMETHYLBORON BROMIDE | ALDEHYDES | PEPTIDE CHEMISTRY | REDUCTIVE AMINATION | ACID FLUORIDES | Peptides | Synthesis | Organic compounds
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 1997, Volume 8, Issue 18, pp. 3043 - 3046
β-Hydroxy-λ-amino acids are a class of non-proteinogenic amino acids present in many important biologically active natural products. In conjunction with our... 
Journal Article
Tetrahedron Asymmetry, ISSN 0957-4166, 09/1997, Volume 8, Issue 18, pp. 3043 - 3046
β-Hydroxy-γ-amino acids are a class of non-proteinogenic amino acids present in many important biologically active natural products. In conjunction with our... 
K EE CHEMISTRY, ORGANIC | PEPTIDOMIMETICS | PEPSTATIN | MIMETICS | ANALOG | DIDEMNIN-B | CHEMISTRY, ORGANIC | CHEMISTRY, PHYSICAL | K EC CHEMISTRY, INORGANIC & NUCLEAR | INHIBITORS | K EI CHEMISTRY, PHYSICAL | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 1996, Volume 6, Issue 22, pp. 2713 - 2716
Based on information from X-ray, NMR, and SAR data, the N,O-diMeTyr 5 unit of didemnim B was believed to interact with receptors. To ascertain the importance... 
CHEMISTRY, ORGANIC | CHEMISTRY, MEDICINAL | IMMUNOSUPPRESSIVE CYCLIC PEPTIDE | INHIBITION | INVIVO
Journal Article
01/1998, ISBN 9780599121164
The didemnins are cyclodepsipeptides isolated from a marine tunicate. Most contain the same twenty-three membered macrocycle and differ only in the side chain... 
Organic chemistry
Dissertation
Tetrahedron: Asymmetry, ISSN 0957-4166, 1994, Volume 5, Issue 4, pp. 519 - 522
An asymmetric Diels-Alder reaction in the presence of 3.0 M lithium perchlorate-diethyl ether was used to generate the initial stereochemistry for a... 
SODIUM TRIACETOXYBOROHYDRIDE | KETONES | DIELS-ALDER REACTIONS | CHEMISTRY, ORGANIC | CHEMISTRY, PHYSICAL | ALDEHYDES | REDUCTIVE AMINATION | RENIN INHIBITORS | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
ChemInform, ISSN 0931-7597, 04/2002, Volume 33, Issue 16, pp. no - no
ChemInform is a weekly ing Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform of an... 
amino acids, peptides
Journal Article
ChemInform, ISSN 0931-7597, 04/1999, Volume 30, Issue 17, pp. no - no
ChemInform is a weekly ing Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform of an... 
pharmacology, medicinal chemistry, vaccines, serums | amino acids, peptides
Journal Article
ChemInform, ISSN 0931-7597, 06/1999, Volume 30, Issue 22, pp. no - no
ChemInform is a weekly ing Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform of an... 
pharmacology, medicinal chemistry, vaccines, serums | amino acids, peptides
Journal Article
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