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Diabetes, ISSN 0012-1797, 2014, Volume 63, Issue 6, pp. 2006 - 2014
Journal Article
Molecules, ISSN 1420-3049, 10/2016, Volume 21, Issue 10, pp. 1290 - 1290
To design new compounds suitable as starting points for anticancer drug development, we have synthesized a novel series of benzoxazoles with pharmaceutically... 
HepaRG hepatocytes | A-549 lung carcinoma cells | Piperazine | Benzoxazole | Fluorine Cytotoxicity | benzoxazole | fluorine Cytotoxicity | POTENT | ANTICANCER AGENTS | piperazine | CHEMISTRY, ORGANIC | ANTITUMOR-ACTIVITY | DERIVATIVES | SCAFFOLD
Journal Article
Diabetes, ISSN 0012-1797, 11/2011, Volume 60, Issue 11, pp. 2740 - 2747
Journal Article
JAMA Pediatrics, ISSN 2168-6203, 09/2013, Volume 167, Issue 9, pp. 800 - 800
  There is evidence for a role of infections within the pathogenesis of islet autoimmunity and type 1 diabetes mellitus (T1D), but previous studies did not... 
Pediatrics | Pathogenesis | Respiratory diseases | Childrens health | Diabetes | Autoimmune diseases | Risk factors | Adolescence
Journal Article
Journal of Biomolecular Screening, ISSN 1087-0571, 1/2013, Volume 18, Issue 1, pp. 67 - 74
Chronic inflammation is at least partially mediated by the chemokine-mediated attraction and by the adhesion molecule–directed binding of leukocytes to the... 
electrical cell substrate impedances sensing (ECIS) | AlphaLISA | chemokine | tumor necrosis factor (TNF) | inflammation | cyanobacteria | high-throughput screening | ICAM-1 | IL-8 | CHEMISTRY, ANALYTICAL | BIOCHEMICAL RESEARCH METHODS | CANCER | TNF | INFLAMMATORY-BOWEL-DISEASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GROWTH | Interleukin-8 - genetics | Cell Adhesion Molecules - genetics | Peptides, Cyclic - isolation & purification | Gene Expression - drug effects | Anti-Inflammatory Agents | Cyanobacteria - chemistry | Humans | Transcriptional Activation - drug effects | Capillary Permeability - drug effects | Endothelium, Vascular - drug effects | Peptides, Cyclic - pharmacology | Depsipeptides - pharmacology | Interleukin-8 - metabolism | Cytokines - genetics | Endothelial Cells - physiology | High-Throughput Screening Assays - methods | Microvessels - cytology | Reproducibility of Results | Cytokines - metabolism | Endothelial Cells - metabolism | Depsipeptides - isolation & purification | Imidazoles - pharmacology | Electric Impedance | Cell Adhesion Molecules - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Intercellular Adhesion Molecule-1 - metabolism | Intercellular Adhesion Molecule-1 - genetics | Tumor Necrosis Factor-alpha - physiology | Pyridines - pharmacology | Kinetics | Lung - blood supply | Endothelial Cells - drug effects | High-throughput screening (Biochemical assaying) | Impedance spectroscopy | Analysis | Endothelium | Cell culture | Edema | Lung | Membrane permeability | Blood vessels | Cytotoxicity | Inflammation | Leukocytes | Drug development | intercellular adhesion molecule 1 | Endothelial cells | Cell adhesion molecules | Side effects | Tumor necrosis factor | Microvasculature | Capillaries | Interleukin 8 | Index Medicus
Journal Article
JAMA Pediatrics, ISSN 2168-6203, 01/2017, Volume 171, Issue 1, pp. 93 - 93
Journal Article
Journal Article
Trends in Food Science & Technology, ISSN 0924-2244, 11/2016, Volume 57, pp. 265 - 272
The human intestinal microbiota is an adaptive entity, being capable of adjusting its phylogenetic and functional profile in response to changes in diet,... 
Obesity | Lifestyle | Microbiota | Microbiome | METABOLITES | INTESTINAL MICROBIOTA | FOOD SCIENCE & TECHNOLOGY | PATTERNS | GUT MICROBIOTA | CHILDREN | DIET | INCREASED RISK | DISEASE | DIVERSITY | Microbiota (Symbiotic organisms) | Epidemiology | Phylogeny
Journal Article
Journal Article
INTERNATIONAL JOURNAL OF CANCER, ISSN 0020-7136, 02/2013, Volume 132, Issue 3, pp. 521 - 530
Metastasis is associated with poor prognosis for melanoma responsible for about 90% of skin cancer-related mortality. To metastasize, melanoma cells must... 
CANCER-CELLS | melanoma progression | ALPHA-CATULIN | EPITHELIAL-MESENCHYMAL TRANSITIONS | MALIGNANT-MELANOMA | BETA-CATENIN | a-catulin | invasion | ONCOLOGY | TUMOR-CELL INVASION | NF-KAPPA-B | UP-REGULATION | EXPRESSION | SNAIL | Fibronectins | Laminin | Genes | Melanoma | Stem cells | Development and progression | Skin | DNA binding proteins | Antigen presentation | Metastasis | Apoptosis | Skin cancer
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 01/2013, Volume 85, Issue 2, pp. 234 - 244
(a) PAK1 orchestrates mesalamine activity, (b) mesalamine inhibits PAK1; increases membranous E-cadherin and β-catenin; modulates cell adhesion Mesalamine... 
Mesalamine | PAK1 | Beta-catenin | E-cadherin | Cell adhesion | ULCERATIVE-COLITIS | MESALAZINE | 5-AMINOSALICYLIC ACID | COLON-CANCER CELLS | INFLAMMATORY-BOWEL-DISEASE | COLORECTAL-CANCER | PHARMACOLOGY & PHARMACY | CATENIN SIGNALING PATHWAY | EXPRESSION | PROGRESSION | Cadherins - metabolism | Colonic Neoplasms - prevention & control | Humans | p21-Activated Kinases - antagonists & inhibitors | Male | Neoplasm Proteins - antagonists & inhibitors | Gene Expression Profiling | Neoplasm Proteins - metabolism | Colonic Neoplasms - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | RNA Interference | Intestinal Polyps - prevention & control | Female | Cadherins - genetics | Neoplasm Proteins - genetics | Anticarcinogenic Agents - pharmacology | Anticarcinogenic Agents - therapeutic use | p21-Activated Kinases - genetics | Cell Adhesion - drug effects | Down-Regulation - drug effects | p21-Activated Kinases - metabolism | beta Catenin - metabolism | beta Catenin - genetics | Mesalamine - pharmacology | Animals | MAP Kinase Signaling System - drug effects | Wnt Signaling Pathway - drug effects | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Colonic Neoplasms - pathology | Intestinal Polyps - pathology | Cell Line, Tumor | Mesalamine - therapeutic use | Mice | Intestinal Polyps - metabolism | Medical colleges | Antifungal agents | Colorectal cancer | Ulcerative colitis | Index Medicus | UC, ulcerative colitis | IBD, inflammatory bowel diseases | CRC, colorectal cancer | PAK1, p21 activated kinase 1 | AJ, adherens junction
Journal Article
Journal Article