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Proceedings of the National Academy of Sciences of the United States of America, ISSN 1091-6490, 2001, Volume 98, Issue 25, pp. 14669 - 14674
.... Dodel † , Feng Gao*, Kelly R. Bales ‡ , Lazarose C. Triarhou § , Eyassu Chernet ‡ , Ken W. Perry ‡ , David L. G. Nelson ‡ , Susan Luecke ‡ , Lee A. Phebus ‡ , Frank... 
Brain | Biological Sciences | Neurotoxicity | Phosphorylation | Disease models | Neurons | Astrocytes | Neuroglia | Substantia nigra | Parkinson disease | Midbrain | TRANSLOCATION | ACTIVATION | INHIBITION | INDUCED APOPTOSIS | NITRIC-OXIDE SYNTHASE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | TOXICITY | NEUROTOXICITY | BRAIN | CEREBELLAR GRANULE CELLS | Minocycline - pharmacology | Humans | Caspase 1 - metabolism | Male | Nitric Oxide Synthase Type II | Neuroprotective Agents - pharmacology | Nerve Degeneration - prevention & control | Parkinsonian Disorders - drug therapy | Neurons - metabolism | Neurons - drug effects | p38 Mitogen-Activated Protein Kinases | Dopamine - metabolism | Mice, Inbred C57BL | Cells, Cultured | Imidazoles - pharmacology | Parkinsonian Disorders - chemically induced | MPTP Poisoning - drug therapy | MPTP Poisoning - prevention & control | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mice | Nitric Oxide Synthase - metabolism | Parkinsonian Disorders - prevention & control | Pyridines - pharmacology | Visual Cortex - drug effects | Nitric Oxide - metabolism | Mitogen-Activated Protein Kinases - metabolism | Monoamine Oxidase - metabolism | Prevention | Parkinson's disease | Minocycline | Physiological aspects | Nervous system | Degeneration | Dopaminergic mechanisms
Journal Article
Journal Article
Psychopharmacology, ISSN 0033-3158, 1/2006, Volume 184, Issue 1, pp. 26 - 35
Journal Article
The Journal of Nuclear Medicine, ISSN 0161-5505, 01/2010, Volume 51, Issue 1, pp. 112 - 120
We recently demonstrated that 11 C-MePPEP, a PET ligand for CB 1 receptors, has such high uptake in the human brain that it can be imaged for 210 min and that... 
Brain imaging neuroimaging | Positron emission tomography | positron emission tomography | brain imaging neuroimaging
Journal Article
Journal Article
Cephalalgia, ISSN 0333-1024, 10/2010, Volume 30, Issue 10, pp. 1159 - 1169
Journal Article
Journal of medicinal chemistry, ISSN 0022-2623, 9/2008, Volume 51, Issue 18, pp. 5833 - 5842
We have reported that [ methyl - 11 C](3 R ,5 R) -5-(3-methoxy-phenyl)-3-(( R )-1-phenyl-ethylamino)-1-(4-trifluoromethyl-phenyl)-pyrrolidin-2-one ([ 11 C] 8 ,... 
Journal Article
Psychopharmacology (Berlin, Germany), ISSN 1432-2072, 2002, Volume 160, Issue 4, pp. 353 - 361
Journal Article
Biological psychiatry (1969), ISSN 0006-3223, 2006, Volume 59, Issue 6, pp. 508 - 515
Knockout (KO) mice invalidated for the dopamine transporter (DAT) constitute a powerful animal model of neurobiological alterations associated with... 
ADHD | dopamine transporter | knockout mice | CB1 receptor | psychosis | anandamide uptake inhibitors | FAAH inhibitors | Psychosis | Knockout mice | Dopamine transporter | Anandamide uptake inhibitors | ENDOGENOUS CANNABINOIDS | ANANDAMIDE | DOPAMINERGIC-NEURONS | RELEASE | NEUROSCIENCES | PREFRONTAL CORTEX | IN-VIVO | ANIMAL-MODEL | BRAIN | TRANSPORT INHIBITOR | CAPSAICIN | Cannabinoid Receptor Modulators - pharmacology | Motor Activity - physiology | Attention Deficit Disorder with Hyperactivity - physiopathology | Capsaicin - pharmacology | Dopamine Plasma Membrane Transport Proteins - drug effects | Motor Activity - drug effects | TRPV Cation Channels - drug effects | Serotonin - pharmacology | Receptor, Cannabinoid, CB1 - physiology | Polyunsaturated Alkamides | Arachidonic Acids - metabolism | Cannabinoid Receptor Modulators - physiology | Dopamine - metabolism | Endocannabinoids | Disease Models, Animal | Dopamine Plasma Membrane Transport Proteins - physiology | TRPV Cation Channels - physiology | Corpus Striatum - physiopathology | Amidohydrolases - antagonists & inhibitors | Capsaicin - analogs & derivatives | Dopamine Plasma Membrane Transport Proteins - genetics | Arachidonic Acids - pharmacology | Mice, Knockout | Animals | Signal Transduction - drug effects | Receptor, Cannabinoid, CB1 - drug effects | Corpus Striatum - drug effects | Serotonin - analogs & derivatives | Signal Transduction - physiology | Mice | Schizophrenia | Health aspects
Journal Article
Psychopharmacology, ISSN 0033-3158, 8/2005, Volume 181, Issue 1, pp. 126 - 133
...Psychopharmacology (2005) 181: 126–133 DOI 10.1007/s00213-005-2198-2 ORIGINAL INVESTIGATION Matthew A. Seager . Vanessa N. Barth . Lee A. Phebus . Kurt... 
Antidepressant | Biomedicine | Olanzapine | Fluoxetine | Antipsychotic | Depression | Bipolar disorder | Pharmacology/Toxicology | Psychiatry | Locus coeruleus | OLANZAPINE/FLUOXETINE COMBINATION | NOREPINEPHRINE | TYROSINE-HYDROXYLASE | PSYCHIATRY | antidepressant | CERULEUS | NORADRENERGIC MODULATION | DEFICIENT MICE | locus coeruleus | NEUROSCIENCES | PREFRONTAL CORTEX | olanzapine | bipolar disorder | fluoxetine | IN-VIVO | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | antipsychotic | SEROTONIN | depression | Serotonin Uptake Inhibitors - pharmacokinetics | Benzodiazepines - blood | Fluoxetine - pharmacokinetics | Bipolar Disorder - physiopathology | Locus Coeruleus - drug effects | Male | Neurons - cytology | Brain - metabolism | Locus Coeruleus - cytology | Injections, Subcutaneous | Neurons - physiology | Neurons - drug effects | Action Potentials - drug effects | Fluoxetine - pharmacology | Benzodiazepines - pharmacology | Infusion Pumps | Injections, Intraperitoneal | Rats | Locus Coeruleus - physiology | Benzodiazepines - pharmacokinetics | Antipsychotic Agents - pharmacokinetics | Rats, Sprague-Dawley | Fluoxetine - blood | Antipsychotic Agents - administration & dosage | Drug Synergism | Bipolar Disorder - etiology | Animals | Serotonin Uptake Inhibitors - administration & dosage | Antipsychotic Agents - pharmacology | Serotonin Uptake Inhibitors - pharmacology | Bipolar Disorder - prevention & control
Journal Article