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1. Full Text 5-year outcomes of transcatheter aortic valve replacement or surgical aortic valve replacement for high surgical risk patients with aortic stenosis (PARTNER 1): a randomised controlled trial
by Mack, Michael J, Prof and Leon, Martin B, Prof and Smith, Craig R, Prof and Miller, D Craig, Prof and Moses, Jeffrey W, Prof and Tuzcu, E Murat, Prof and Webb, John G, Prof and Douglas, Pamela S, Prof and Anderson, William N, PhD and Blackstone, Eugene H, MD and Kodali, Susheel K, MD and Makkar, Raj R, MD and Fontana, Gregory P, MD and Kapadia, Samir, Prof and Bavaria, Joseph, Prof and Hahn, Rebecca T, MD and Thourani, Vinod H, Prof and Babaliaros, Vasilis, MD and Pichard, Augusto, Prof and Herrmann, Howard C, Prof and Brown, David L, MD and Williams, Mathew, MD and Davidson, Michael J, MD and Svensson, Lars G, Prof and Akin, Jodi and PARTNER 1 Trial Investigators and PARTNER 1 trial investigators
Lancet, The, ISSN 0140-6736, 2015, Volume 385, Issue 9986, pp. 2477 - 2484
Summary Background The Placement of Aortic Transcatheter Valves (PARTNER) trial showed that mortality at 1 year, 2 years, and 3 years is much the same with... 
Internal Medicine | DURABILITY | MEDICINE, GENERAL & INTERNAL | MULTICENTER | IMPLANTATION IMPACT | REGURGITATION | LONG-TERM OUTCOMES | INOPERABLE PATIENTS | SAPIEN 3 | TAVR | Follow-Up Studies | Comorbidity | United States | Humans | Heart Valve Prosthesis Implantation - methods | Heart Valve Prosthesis Implantation - mortality | Male | Survival Rate | Treatment Outcome | Aortic Valve - surgery | Cause of Death | Canada | Aortic Valve Stenosis - epidemiology | Survival Analysis | Aged, 80 and over | Female | Aged | Aortic Valve Stenosis - surgery | Transcatheter Aortic Valve Replacement - mortality | Aortic Valve Insufficiency - epidemiology | Germany | Transcatheter Aortic Valve Replacement - methods | Clinical trials | Medical colleges | Aortic valve stenosis | Patient outcomes | Mortality | Cardiology | Heart surgery | Coronary vessels | Catheters | Clinical outcomes
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2. Full Text 5-year outcomes of transcatheter aortic valve replacement compared with standard treatment for patients with inoperable aortic stenosis (PARTNER 1): a randomised controlled trial
by Kapadia, Samir R, Prof and Leon, Martin B, Prof and Makkar, Raj R, MD and Tuzcu, E Murat, Prof and Svensson, Lars G, Prof and Kodali, Susheel, MD and Webb, John G, Prof and Mack, Michael J, Prof and Douglas, Pamela S, Prof and Thourani, Vinod H, Prof and Babaliaros, Vasilis C, MD and Herrmann, Howard C, Prof and Szeto, Wilson Y, MD and Pichard, Augusto D, MD and Williams, Mathew R, MD and Fontana, Gregory P, MD and Miller, D Craig, Prof and Anderson, William N, PhD and Smith, Craig R, Prof and Akin, Jodi J and Davidson, Michael J and PARTNER Trial Investigators and PARTNER trial investigators
Lancet, The, ISSN 0140-6736, 2015, Volume 385, Issue 9986, pp. 2485 - 2491
Summary Background Based on the early results of the Placement of Aortic Transcatheter Valves (PARTNER) trial, transcatheter aortic valve replacement (TAVR) is... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | IMPLANTATION | PREDICTORS | LONG-TERM OUTCOMES | TAVI | Follow-Up Studies | United States | Humans | Male | Aortic Valve - surgery | Cause of Death | Aortic Valve Stenosis - diagnostic imaging | Aortic Valve Stenosis - epidemiology | Aged, 80 and over | Female | Stroke - epidemiology | Aortic Valve Stenosis - surgery | Echocardiography | Aortic Valve - diagnostic imaging | Risk Assessment | Comorbidity | Aortic Valve Stenosis - physiopathology | Kaplan-Meier Estimate | Aortic Valve - physiopathology | Survival Rate | Treatment Outcome | Canada | Aged | Hemodynamics | Transcatheter Aortic Valve Replacement - mortality | Germany | Clinical trials | Medical colleges | Comparative analysis | Aortic valve stenosis | Patient outcomes | Comparative studies | Cardiology | Heart surgery | Coronary vessels | Catheters | Clinical outcomes
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3. Full Text Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients
by Smith, Craig R and Leon, Martin B and Mack, Michael J and Miller, D. Craig and Moses, Jeffrey W and Svensson, Lars G and Tuzcu, E. Murat and Webb, John G and Fontana, Gregory P and Makkar, Raj R and Williams, Mathew and Dewey, Todd and Kapadia, Samir and Babaliaros, Vasilis and Thourani, Vinod H and Corso, Paul and Pichard, Augusto D and Bavaria, Joseph E and Herrmann, Howard C and Akin, Jodi J and Anderson, William N and Wang, Duolao and Pocock, Stuart J and PARTNER Trial Investigators
The New England Journal of Medicine, ISSN 0028-4793, 06/2011, Volume 364, Issue 23, pp. 2187 - 2198
This study examines use of an expandable bovine pericardial prosthetic valve inserted with a catheter system for valvular aortic stenosis. Outcomes were... 
MEDICINE, GENERAL & INTERNAL | STENOSIS | VENTRICULAR-FUNCTION | IMPLANTATION | HEART-VALVE | EXPERIENCE | OUTCOMES | ELDERLY-PATIENTS | PROSTHESIS | THORACIC SURGEONS | AGE | Catheterization | Humans | Risk Factors | Cardiac Catheterization - adverse effects | Heart Valve Prosthesis Implantation - methods | Male | Aortic Valve - surgery | Aortic Valve Stenosis - therapy | Aortic Valve Stenosis - mortality | Stroke - etiology | Heart Valve Prosthesis Implantation - adverse effects | Intention to Treat Analysis | Aged, 80 and over | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Female | Stroke - epidemiology | Aged | Aortic Valve Stenosis - surgery | Postoperative Complications | Care and treatment | Diagnosis | Health aspects | Aortic valve stenosis | Patient outcomes | Heart valve replacement | Studies | Fibrillation | Risk groups | Mortality | Clinical trials | Stenosis | Cardiovascular disease | Aorta | Risk factors | Catheters
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4. Full Text Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery
by Leon, Martin B and Smith, Craig R and Mack, Michael and Miller, D. Craig and Moses, Jeffrey W and Svensson, Lars G and Tuzcu, E. Murat and Webb, John G and Fontana, Gregory P and Makkar, Raj R and Brown, David L and Block, Peter C and Guyton, Robert A and Pichard, Augusto D and Bavaria, Joseph E and Herrmann, Howard C and Douglas, Pamela S and Petersen, John L and Akin, Jodi J and Anderson, William N and Wang, Duolao and Pocock, Stuart and PARTNER Trial Investigators
The New England Journal of Medicine, ISSN 0028-4793, 10/2010, Volume 363, Issue 17, pp. 1597 - 1607
Patients with aortic stenosis underwent transfemoral transcatheter implantation of a balloon-expandable bovine pericardial aortic valve. One-year mortality was... 
REPLACEMENT | MORTALITY | SURVIVAL | MEDICINE, GENERAL & INTERNAL | HIGH-RISK PATIENTS | HEART-VALVE | EXPERIENCE | ELDERLY-PATIENTS | PROSTHESIS | THORACIC SURGEONS | PROGRESSION | Echocardiography | Prospective Studies | Catheterization | Humans | Kaplan-Meier Estimate | Heart Valve Prosthesis Implantation - methods | Male | Treatment Outcome | Hospitalization | Aortic Valve Stenosis - therapy | Aortic Valve Stenosis - mortality | Cardiac Catheterization | Aged, 80 and over | Cardiovascular Diseases - mortality | Female | Aged | Aortic Valve Stenosis - surgery | Cardiac catheterization | Care and treatment | Health aspects | Aortic valve stenosis | Patient outcomes | Cardiovascular disease | Candidates | Patients | Surgery
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5. Full Text Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients
by Leon, Martin B and Smith, Craig R and Mack, Michael J and Makkar, Raj R and Svensson, Lars G and Kodali, Susheel K and Thourani, Vinod H and Tuzcu, E. Murat and Miller, D. Craig and Herrmann, Howard C and Doshi, Darshan and Cohen, David J and Pichard, Augusto D and Kapadia, Samir and Dewey, Todd and Babaliaros, Vasilis and Szeto, Wilson Y and Williams, Mathew R and Kereiakes, Dean and Zajarias, Alan and Greason, Kevin L and Whisenant, Brian K and Hodson, Robert W and Moses, Jeffrey W and Trento, Alfredo and Brown, David L and Fearon, William F and Pibarot, Philippe and Hahn, Rebecca T and Jaber, Wael A and Anderson, William N and Alu, Maria C and Webb, John G and PARTNER 2 Investigators
The New England Journal of Medicine, ISSN 0028-4793, 04/2016, Volume 374, Issue 17, pp. 1609 - 1620
In a randomized trial involving more than 2000 patients, transcatheter aortic-valve replacement was noninferior to surgical replacement in the primary end... 
MEDICINE, GENERAL & INTERNAL | STENOSIS | IMPLANTATION | TRANSFEMORAL TRANSCATHETER | COMPLICATIONS | SOCIETY | TAVR | CLINICAL-OUTCOMES | INSIGHTS | Multivariate Analysis | Transcatheter Aortic Valve Replacement | Heart Valve Prosthesis | Humans | Risk Factors | Kaplan-Meier Estimate | Heart Valve Prosthesis Implantation - methods | Heart Valve Prosthesis Implantation - mortality | Male | Postoperative Complications - mortality | Aortic Valve Stenosis - diagnostic imaging | Aortic Valve Stenosis - mortality | Stroke - etiology | Ultrasonography | Aged, 80 and over | Female | Aged | Aortic Valve Stenosis - surgery | Stroke - mortality | Surgical techniques | Fibrillation | Risk groups | Heart surgery | Coronary vessels | Surgery | Regurgitation | Clinical trials | Stenosis | Cardiovascular disease | Death | Aorta
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6. Full Text Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves
by Makkar, Raj R and Fontana, Gregory and Jilaihawi, Hasan and Chakravarty, Tarun and Kofoed, Klaus F and de Backer, Ole and Asch, Federico M and Ruiz, Carlos E and Olsen, Niels T and Trento, Alfredo and Friedman, John and Berman, Daniel and Cheng, Wen and Kashif, Mohammad and Jelnin, Vladimir and Kliger, Chad A and Guo, Hongfei and Pichard, Augusto D and Weissman, Neil J and Kapadia, Samir and Manasse, Eric and Bhatt, Deepak L and Leon, Martin B and Søndergaard, Lars
The New England Journal of Medicine, ISSN 0028-4793, 11/2015, Volume 373, Issue 21, pp. 2015 - 2024
Reduced leaflet motion was detected on computed tomography in 22 patients in a clinical trial of transcatheter aortic-valve replacement (TAVR) and in 17... 
REPLACEMENT | MEDICINE, GENERAL & INTERNAL | STENOSIS | RECOMMENDATIONS | IMPLANTATION | RISK | ECHOCARDIOGRAPHY | EUROPEAN ASSOCIATION | TRANSCATHETER | Aortic Valve - diagnostic imaging | Humans | Heart Valve Prosthesis - adverse effects | Aortic Valve - physiopathology | Bioprosthesis - adverse effects | Anticoagulants - therapeutic use | Male | Aortic Valve - surgery | Heart Valve Diseases - etiology | Four-Dimensional Computed Tomography | Stroke - etiology | Thrombosis - etiology | Ischemic Attack, Transient - etiology | Aged, 80 and over | Female | Registries | Aged | CT imaging | Care and treatment | Usage | Clinical trials | Anticoagulants (Medicine) | Dosage and administration | Thrombosis | Blood clot | Anticoagulants | Warfarin | Stroke | Transplants & implants | Computed tomography | Ischemia | Coronary vessels | Data processing | Aorta
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7. Full Text Will TAVR Become the Default Treatment for Patients With Severe Aortic Stenosis?
by Waksman, Ron, MD and Pichard, Augusto D., MD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2015, Volume 66, Issue 2, pp. 122 - 124
  [...]of these studies, the U.S. Food and Drug Administration granted approval for the marketing of TAVR, and it has become the standard of care in patients... 
Cardiovascular | Internal Medicine | severe aortic stenosis | SAVR | structural heart disease | TAVR | CARDIAC & CARDIOVASCULAR SYSTEMS | VALVE-REPLACEMENT | 2-YEAR OUTCOMES | TRANSCATHETER | Female | Male | Aortic Valve Stenosis - therapy | Humans | Studies | Cardiology | Mortality | Surgery
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