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science & technology (48) 48
life sciences & biomedicine (38) 38
humans (33) 33
cell biology (19) 19
biochemistry & molecular biology (17) 17
telomeres (17) 17
telomerase (15) 15
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science (7) 7
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alternative lengthening of telomeres (6) 6
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biology (4) 4
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fundamental and applied biological sciences. psychology (4) 4
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medicine (4) 4
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rna, messenger - genetics (4) 4
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alleles (3) 3
alt (3) 3
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1. Full Text Molecular mechanisms of activity and derepression of alternative lengthening of telomeres
by Pickett, Hilda A and Reddel, Roger R
Nature structural & molecular biology, ISSN 1545-9993, 11/2015, Volume 22, Issue 11, pp. 875 - 880
Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | DNA Helicases - metabolism | Homologous Recombination | Nuclear Proteins - metabolism | Telomere - metabolism | Telomere Homeostasis | Cellular proteins | DNA synthesis | Research | Chromosomes | Cellular biology | Telomerase | Deoxyribonucleic acid--DNA | Index Medicus
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2. Full Text Alternative Lengthening of Telomeres: DNA Repair Pathways Converge
by Sobinoff, Alexander P and Pickett, Hilda A
Trends in genetics, ISSN 0168-9525, 12/2017, Volume 33, Issue 12, pp. 921 - 932
ALT | replication stress | recombination | break-induced telomere synthesis | DNA damage response | telomere | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Animals | Humans | DNA Replication - genetics | Homologous Recombination - genetics | DNA Repair - genetics | Telomere Homeostasis - genetics | Telomere - genetics | Telomeres | DNA repair | Genomics | DNA | DNA damage | Index Medicus
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3. Full Text NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination
by Conomos, Dimitri and Conomos, Dimitri and Reddel, Roger R and Reddel, Roger R and Pickett, Hilda A and Pickett, Hilda A
Nature structural & molecular biology, ISSN 1545-9993, 09/2014, Volume 21, Issue 9, pp. 760 - 770
Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | DNA-Binding Proteins - metabolism | Cell Line | Cell Cycle | Humans | Chromatin Assembly and Disassembly | Homologous Recombination | Mi-2 Nucleosome Remodeling and Deacetylase Complex - metabolism | Telomere - metabolism | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Apoptosis | Gene Knockdown Techniques | Chromosome replication | Physiological aspects | Genetic research | Telomeres | Research | Genetic translation | Proteins | Chromatin | Cellular biology | Molecular biology | Index Medicus
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4. Full Text The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)
by Lu, Robert and O’Rourke, Julienne J and Sobinoff, Alexander P and Allen, Joshua A. M and Nelson, Christopher B and Tomlinson, Christopher G and Lee, Michael and Reddel, Roger R and Deans, Andrew J and Pickett, Hilda A
Nature communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2252 - 2252
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neoplasms - metabolism | DNA Topoisomerases, Type I - metabolism | RecQ Helicases - metabolism | HCT116 Cells | Humans | DNA Replication | Nuclear Proteins - metabolism | Telomere Homeostasis | DNA-Binding Proteins - metabolism | DNA Helicases - metabolism | Carrier Proteins - metabolism | HEK293 Cells | Cell Line, Tumor | Telomere - metabolism | HeLa Cells | Collapse | Complex formation | Stability | Anemia | Translocase | Fanconi syndrome | Substrates | Stress | Genomic instability | Replication forks | DNA biosynthesis | Telomeres | Depletion | Synthesis | Biomarkers | Replication | Attenuation | Telomerase | Deoxyribonucleic acid--DNA | Cancer | Index Medicus
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5. Full Text Mechanisms that drive telomere maintenance and recombination in human cancers
by Sobinoff, Alexander P and Pickett, Hilda A
Current opinion in genetics & development, ISSN 0959-437X, 02/2020, Volume 60, pp. 25 - 30
Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus
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6. Full Text Whole-genome landscapes of major melanoma subtypes
by Hayward, Nicholas K and Hayward, Nicholas K and Wilmott, James S and Wilmott, James S and Waddell, Nicola and Waddell, Nicola and Johansson, Peter A and Johansson, Peter A and Field, Matthew A and Field, Matthew A and Nones, Katia and Nones, Katia and Patch, Ann-Marie and Patch, Ann-Marie and Kakavand, Hojabr and Kakavand, Hojabr and Alexandrov, Ludmil B and Alexandrov, Ludmil B and Burke, Hazel and Burke, Hazel and Jakrot, Valerie and Jakrot, Valerie and Kazakoff, Stephen and Kazakoff, Stephen and Holmes, Oliver and Holmes, Oliver and Leonard, Conrad and Leonard, Conrad and Sabarinathan, Radhakrishnan and Sabarinathan, Radhakrishnan and Mularoni, Loris and Mularoni, Loris and Wood, Scott and Wood, Scott and Xu, Qinying and Xu, Qinying and Waddell, Nick and Waddell, Nick and Tembe, Varsha and Tembe, Varsha and Pupo, Gulietta M and Pupo, Gulietta M and De Paoli-Iseppi, Ricardo and De Paoli-Iseppi, Ricardo and Vilain, Ricardo E and Vilain, Ricardo E and Shang, Ping and Shang, Ping and Lau, Loretta M S and Lau, Loretta M. S and Dagg, Rebecca A and Dagg, Rebecca A and Schramm, Sarah-Jane and Schramm, Sarah-Jane and Pritchard, Antonia and Pritchard, Antonia and Dutton-Regester, Ken and Dutton-Regester, Ken and Newell, Felicity and Newell, Felicity and Fitzgerald, Anna and Fitzgerald, Anna and Shang, Catherine A and Shang, Catherine A and Grimmond, Sean M and Grimmond, Sean M and Pickett, Hilda A and Pickett, Hilda A and Yang, Jean Y and Yang, Jean Y and Stretch, Jonathan R and Stretch, Jonathan R and Behren, Andreas and Behren, Andreas and Kefford, Richard F and Kefford, Richard F and Hersey, Peter and Hersey, Peter and Long, Georgina V and Long, Georgina V and Cebon, Jonathan and Cebon, Jonathan and Shackleton, Mark and Shackleton, Mark and Spillane, Andrew J and Spillane, Andrew J and Saw, Robyn P. M and Saw, Robyn P M and López-Bigas, Núria and López-Bigas, Núria and Pearson, John V and Pearson, John V and Thompson, John F and Thompson, John F and Scolyer, Richard A and Scolyer, Richard A and Mann, Graham J and Mann, Graham J and Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Nature (London), ISSN 0028-0836, 05/2017, Volume 545, Issue 7653, pp. 175 - 180
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Membrane Proteins - genetics | Humans | X-linked Nuclear Protein | Phosphoproteins - genetics | RNA Splicing Factors - genetics | Mutation - genetics | Genes, p16 | Genome, Human - genetics | Tumor Suppressor Protein p53 - genetics | Ultraviolet Rays - adverse effects | Telomerase - genetics | Signal Transduction - drug effects | GTP Phosphohydrolases - genetics | Melanoma - genetics | Proto-Oncogene Proteins B-raf - genetics | Mitogen-Activated Protein Kinases - genetics | Neurofibromatosis 1 - genetics | Melanoma - classification | Nuclear Proteins - genetics | DNA Helicases - genetics | Telomere - genetics | Genetic research | Genetic aspects | Genomes | Research | Melanoma | Pathogenesis | Copy number | Mucosa | p53 Protein | Radiation | Security | Epidemiology | Metastases | Scholarships & fellowships | Reproduction (copying) | Coding | Mismatch repair | Clusters | Eye (anatomy) | Deoxyribonucleic acid--DNA | Medical research | Breakpoints | Radiation effects | MAP kinase | Exposure | Sun | Amplification | Bridges | Pathology | Ultraviolet radiation | Mutagenesis | Computation | Skin | Mutation | Internet | Aberration | Biotechnology | Genes | DNA damage | Carcinogens | Infrastructure | Signatures | Health | U.V. radiation | Inversions | Foldback | Data processing | Energy policy | Readers | Deamination | Protein kinase | Cell lines | Gene mapping | Tumors | Cancer | Index Medicus | Biological Science | 60 APPLIED LIFE SCIENCES
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7. Full Text BLM and SLX4 play opposing roles in recombination‐dependent replication at human telomeres
by Sobinoff, Alexander P and Allen, Joshua AM and Neumann, Axel A and Yang, Sile F and Walsh, Monica E and Henson, Jeremy D and Reddel, Roger R and Pickett, Hilda A
The EMBO journal, ISSN 0261-4189, 10/2017, Volume 36, Issue 19, pp. 2907 - 2919
ALT | BLM | SLX4 | telomere recombination | telomere synthesis | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Recombinases - metabolism | DNA Topoisomerases, Type I - metabolism | RecQ Helicases - metabolism | Humans | Cells, Cultured | Multienzyme Complexes - metabolism | DNA Topoisomerases, Type I - physiology | Telomere Homeostasis - genetics | Recombinases - physiology | Multienzyme Complexes - physiology | DNA Replication - genetics | Recombination, Genetic - genetics | DNA-Directed DNA Polymerase - physiology | Telomere - metabolism | DNA-Directed DNA Polymerase - metabolism | RecQ Helicases - physiology | Exchanging | Recombination | Mesenchyme | Tumor cells | Dissolution | Intermediates | DNA biosynthesis | DNA helicase | Telomeres | Synthesis | Replication | Endonuclease | Telomerase | Chromosomes | Deoxyribonucleic acid--DNA | Tumors | Index Medicus | DNA Replication, Repair & Recombination
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8. Full Text Author Correction: The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)
by Lu, Robert and O’Rourke, Julienne J and Sobinoff, Alexander P and Allen, Joshua A. M and Nelson, Christopher B and Tomlinson, Christopher G and Lee, Michael and Reddel, Roger R and Deans, Andrew J and Pickett, Hilda A
Nature communications, ISSN 2041-1723, 11/2019, Volume 10, Issue 1, pp. 1 - 1
Telomeres | Index Medicus
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9. Full Text Whole-genome landscape of pancreatic neuroendocrine tumours
by Scarpa, Aldo and Chang, David K and Nones, Katia and Corbo, Vincenzo and Patch, Ann-Marie and Bailey, Peter and Lawlor, Rita T and Johns, Amber L and Miller, David K and Mafficini, Andrea and Rusev, Borislav and Scardoni, Maria and Antonello, Davide and Barbi, Stefano and Sikora, Katarzyna O and Cingarlini, Sara and Vicentini, Caterina and McKay, Skye and Quinn, Michael C.J and Bruxner, Timothy J.C and Christ, Angelika N and Harliwong, Ivon and Idrisoglu, Senel and McLean, Suzanne and Nourse, Craig and Nourbakhsh, Ehsan and Wilson, Peter J and Anderson, Matthew J and Fink, J. Lynn and Newell, Felicity and Waddell, Nick and Holmes, Oliver and Kazakoff, Stephen H and Leonard, Conrad and Wood, Scott and Xu, Qinying and Nagaraj, Shivashankar Hiriyur and Amato, Eliana and Dalai, Irene and Bersani, Samantha and Cataldo, Ivana and Dei Tos, Angelo P and Capelli, Paola and Davì, Maria Vittoria and Landoni, Luca and Malpaga, Anna and Miotto, Marco and Whitehall, Vicki L.J and Leggett, Barbara A and Harris, Janelle L and Harris, Jonathan and Jones, Marc D and Humphris, Jeremy and Chantrill, Lorraine A and Chin, Venessa and Nagrial, Adnan M and Pajic, Marina and Scarlett, Christopher J and Pinho, Andreia and Rooman, Ilse and Toon, Christopher and Wu, Jianmin and Pinese, Mark and Cowley, Mark and Barbour, Andrew and Mawson, Amanda and Humphrey, Emily S and Colvin, Emily K and Chou, Angela and Lovell, Jessica A and Jamieson, Nigel B and Duthie, Fraser and Gingras, Marie-Claude and Fisher, William E and Dagg, Rebecca A and Lau, Loretta M.S and Lee, Michael and Pickett, Hilda A and Reddel, Roger R and Samra, Jaswinder S and Kench, James G and Merrett, Neil D and Epari, Krishna and Nguyen, Nam Q and Zeps, Nikolajs and Falconi, Massimo and Simbolo, Michele and Butturini, Giovanni and Van Buren, George and Partelli, Stefano and Fassan, Matteo and Khanna, Kum Kum and Gill, Anthony J and Wheeler, David A and Gibbs, Richard A and Musgrove, Elizabeth A and Bassi, Claudio and Tortora, Giampaolo and Pederzoli, Paolo and Pearson, John V and ... and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature (London), ISSN 0028-0836, 03/2017, Volume 543, Issue 7643, pp. 65 - 71
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Calmodulin-Binding Proteins - genetics | RNA-Binding Proteins - genetics | TOR Serine-Threonine Kinases - metabolism | Genomics | Humans | DNA Glycosylases - genetics | Carcinoma, Neuroendocrine - genetics | Chromatin Assembly and Disassembly - genetics | Male | Pancreatic Neoplasms - genetics | DNA Copy Number Variations - genetics | DNA Repair - genetics | Germ-Line Mutation - genetics | Genome, Human - genetics | DNA Mutational Analysis | Base Sequence | Chromosome Aberrations | Female | Telomere - metabolism | RNA-Binding Protein EWS | Telomere - genetics | Genetic aspects | Nucleotide sequencing | Pancreatic cancer | Methods | DNA sequencing | Genes | Biomarkers | Genomes | Mutation | Signatures | Patients | Tumors | Index Medicus
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