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1. Full Text Making the White man's West
: Whiteness and the creation of the American West
by Pierce, Jason (Jason Eric)
2016, ISBN 1607323958, xxv, 296
"The West, especially the Intermountain states, ranks among the whitest places in America, but this fact obscures the more complicated history of racial... 
Cultural pluralism | British Americans | Race identity | Frontier and pioneer life | West (U.S.) History | Whites | History | Racism | West (U.S.) Race relationsHistory | 20th century | West (U.S.) | 19th century | Race relations | British Americans - West (U.S.) - History | HISTORY / United States / State & Local / West (AK, CA, CO, HI, ID, MT, NV, UT, WY) | Cultural Studies
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2. Improving America's schools
: the role of incentives
by Hanushek, Eric A. 1943- (Eric Alan) and Jorgenson, Dale W. 1933- (Dale Weldeau)
1996, ISBN 0309054362, viii, 268
Educational change | School improvement programs | School management and organization
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3. Philosophy imprisoned
: the love of wisdom in the age of mass incarceration
by Tyson, Sarah, editor
2014, ISBN 9780739189481, vii, 334
Prisons | Imprisonment | Social aspects | Philosophy
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4. Full Text Genome Editing for Inherited Retinal Degenerations
by Pierce, Eric
Ophthalmology, ISSN 0161-6420, 09/2018, Volume 125, Issue 9, pp. 1431 - 1432
OPHTHALMOLOGY
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5. Full Text The Status ofRPE65Gene Therapy Trials: Safety and Efficacy
by Pierce, Eric A and Bennett, Jean
Cold Spring Harbor Perspectives in Medicine, ISSN 2157-1422, 09/2015, Volume 5, Issue 9, p. a017285
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6. Full Text C3a triggers formation of sub-retinal pigment epithelium deposits via the ubiquitin proteasome pathway
by Fernandez-Godino, Rosario and Pierce, Eric A
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 9679 - 14
The mechanisms that connect complement system activation and basal deposit formation in early stages of age-related macular degeneration (AMD) are... 
PATHOGENESIS | SYSTEM | DRUSEN | INHIBITION | COMPLEMENT ACTIVATION | MULTIDISCIPLINARY SCIENCES | RECEPTOR | BRUCHS MEMBRANE | MODEL | APOLIPOPROTEIN-B | HUMAN RETINA | Ubiquitin | Complement receptors | Deposits | Complement component C3a | Fetuses | Retina | Epithelium | Retinal pigment epithelium | Gelatinase A | Macular degeneration | Complement activation | Complement component C3 | Collagen | Extracellular matrix | Degeneration | Age
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7. Full Text Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial
by Bennett, Jean, Prof and Wellman, Jennifer, MSc and Marshall, Kathleen A, COT and McCague, Sarah, BA and Ashtari, Manzar, PhD and DiStefano-Pappas, Julie, BA and Elci, Okan U, PhD and Chung, Daniel C, DO and Sun, Junwei, MSc and Wright, J Fraser, PhD and Cross, Dominique R, MPH and Aravand, Puya, BA and Cyckowski, Laura L, BA and Bennicelli, Jeannette L, PhD and Mingozzi, Federico, PhD and Auricchio, Alberto, MD and Pierce, Eric A, MD and Ruggiero, Jason, MD and Leroy, Bart P, Prof and Simonelli, Francesca, Prof and High, Katherine A, MD and Maguire, Albert M, Prof
Lancet, The, ISSN 0140-6736, 2016, Volume 388, Issue 10045, pp. 661 - 672
Summary Background Safety and efficacy have been shown in a phase 1 dose-escalation study involving a unilateral subretinal injection of a recombinant... 
Internal Medicine | RETINAL DEGENERATION | VISUAL CYCLE | MEDICINE, GENERAL & INTERNAL | LEBER CONGENITAL AMAUROSIS | CANINE MODEL | VISION | ADENOASSOCIATED VIRUS | ROD | IMPROVEMENT | Administration, Ophthalmic | Follow-Up Studies | Blindness - physiopathology | Humans | Middle Aged | Blindness - pathology | Male | Occipital Lobe - physiopathology | Retinal Cone Photoreceptor Cells - pathology | Patient Safety | Adult | Female | Blindness - therapy | Child | Linear Models | Dependovirus | Evidence-Based Medicine | Blindness - genetics | Retreatment | cis-trans-Isomerases - genetics | Vision, Ocular | Adolescent | Age of Onset | Mutation | Genetic Vectors | Injections, Intraocular | Retinal Rod Photoreceptor Cells - pathology | Genetic Therapy - adverse effects | Genetic Therapy - methods | Genetic vectors | Genes | Blindness | Genetic research | Genetic aspects | Ophthalmology | Gene therapy | Studies | Retina | Genomes | Children & youth | Index Medicus | Abridged Index Medicus
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8. Full Text Characterizing variants of unknown significance in rhodopsin: A functional genomics approach
by Wan, Aliete and Place, Emily and Pierce, Eric A and Comander, Jason
Human Mutation, ISSN 1059-7794, 08/2019, Volume 40, Issue 8, pp. 1127 - 1144
Characterizing the pathogenicity of DNA sequence variants of unknown significance (VUS) is a major bottleneck in human genetics, and is increasingly important... 
rhodopsin | inherited retinal diseases | variant pathogenicity, variant of unknown significance | VUS | retinitis pigmentosa | variant library | functional genomics | next‐generation sequencing | next-generation sequencing | variant pathogenicity | variant of unknown significance | STABILITY | MECHANISMS | BLINDNESS | DOMINANT RETINITIS-PIGMENTOSA | MUTANTS | MOLECULAR DIAGNOSIS | PHARMACOLOGICAL MANIPULATION | DISEASE | GENETICS & HEREDITY | ENDOPLASMIC-RETICULUM | MUTATIONS | Medical research | Rhodopsin | Genomics | Genetic research | Medicine, Experimental | Nucleotide sequencing | DNA sequencing | Pathogenicity | Flow cytometry | Nucleotide sequence | Retinitis pigmentosa | Retina | Retinitis | Gene therapy | Cell surface | Genetic screening | Index Medicus
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9. Full Text Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial
by Maguire, Albert M, MD and High, Katherine A, Prof and Auricchio, Alberto, Prof and Wright, J Fraser, PhD and Pierce, Eric A, MD and Testa, Francesco, MD and Mingozzi, Federico, PhD and Bennicelli, Jeannette L, PhD and Ying, Gui-shuang, PhD and Rossi, Settimio, MD and Fulton, Ann, Prof and Marshall, Kathleen A, COT and Banfi, Sandro, MD and Chung, Daniel C, DO and Morgan, Jessica IW, PhD and Hauck, Bernd, PhD and Zelenaia, Olga, PhD and Zhu, Xiaosong, MD and Raffini, Leslie, MD and Coppieters, Frauke, PhD and De Baere, Elfride, PhD and Shindler, Kenneth S, MD and Volpe, Nicholas J, Prof and Surace, Enrico M, DVM and Acerra, Carmela, BA and Lyubarsky, Arkady, PhD and Redmond, T Michael, PhD and Stone, Edwin, Prof and Sun, Junwei, MBA and McDonnell, Jennifer Wellman, MS and Leroy, Bart P, Prof and Simonelli, Francesca, MD and Bennett, Jean, Prof
Lancet, The, ISSN 0140-6736, 2009, Volume 374, Issue 9701, pp. 1597 - 1605
Summary Background Gene therapy has the potential to reverse disease or prevent further deterioration of vision in patients with incurable inherited retinal... 
Internal Medicine | VISUAL CYCLE | ISOMEROHYDROLASE | MEDICINE, GENERAL & INTERNAL | VISION | SAFETY | ROD | KINETICS | ISOMERASE | MUTATIONS | RETINITIS-PIGMENTOSA | BLINDNESS | Dependovirus - genetics | Nystagmus, Physiologic | Age Factors | Humans | Male | Optic Atrophy, Hereditary, Leber - genetics | Genetic Vectors - therapeutic use | Dark Adaptation | Dose-Response Relationship, Drug | Young Adult | Adult | Female | Blindness - congenital | Eye Proteins - genetics | Optic Atrophy, Hereditary, Leber - diagnosis | Safety | Child | cis-trans-Isomerases | Electroretinography | Treatment Outcome | Optic Atrophy, Hereditary, Leber - therapy | Mutation - genetics | Visual Acuity | Blindness - genetics | Disease Progression | Genetic Vectors - genetics | Carrier Proteins - genetics | Injections | Adolescent | Genetic Therapy - methods | Usage | Care and treatment | Genetic aspects | Leber's congenital amaurosis | Gene therapy | Health aspects | Studies | Eye movements | Patients | Eyes & eyesight | Light | Blindness | Index Medicus | Abridged Index Medicus
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10. Full Text TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum
by Blakesley, Robert W and Hildebrandt, Friedhelm and Maskeri, Baishali and Attié-Bitach, Tania and Hansen, Nancy F and Gyapay, Gabor and Cherukuri, Praveen and Gleeson, Joseph G and Zhang, Qi and Szymanska, Katarzyna and Katsanis, Nicholas and Wheeler, David A and Tönshoff, Burkhard and Ramaswami, Gokul and Mullikin, James C and Liu, Qin and Scambler, Peter J and Davey, Lisa M and Lewis, Richard A and Soliman, Neveen A and Neuhaus, Thomas J and Maher, Eamonn R and Pierce, Eric A and Davis, Erica E and Rieger, Susanne and Gallagher, Tomas E and Diplas, Bill H and Muzny, Donna M and Green, Eric D and Young, Alice C and Lewis, Lora R and Kayserili, Hulya and Kern, Ilse and Saunier, Sophie and Dollfus, Hélène and Gibbs, Richard A and Morgan, Margaret and Cruz, Pedro and Beales, Philip L and Hartley, Jane and Bouffard, Gerard G and Stoetzel, Corinne and Swoboda, Kathryn J and Johnson, Colin A and Logan, Clare V and Otto, Edgar A and Bergmann, Carsten and NISC Comparative Sequencing Progra and NISC Comparative Sequencing Program
Nature Genetics, ISSN 1061-4036, 03/2011, Volume 43, Issue 3, pp. 189 - 196
Ciliary dysfunction leads to a broad range of overlapping phenotypes, collectively termed ciliopathies. This grouping is underscored by genetic overlap, where... 
RETROGRADE INTRAFLAGELLAR TRANSPORT | JOUBERT-SYNDROME | RETINAL DEGENERATION | GENE | MECKEL-SYNDROME | IN-VIVO | GENETICS & HEREDITY | BARDET-BIEDL-SYNDROME | NEPHRONOPHTHISIS | MUTATIONS | CENTROSOMAL PROTEIN | Genetic Variation | Animals | Pedigree | Humans | Adaptor Proteins, Signal Transducing - genetics | Alleles | Mice | Mutation | Photoreceptor Cells - physiology | Zebrafish - genetics | Ciliary Motility Disorders - genetics | Allelomorphism | Genetic disorders | Gene mutations | Cilia and ciliary motion | Genetic aspects | Research | Health aspects | Zebrafish | Index Medicus
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11. Full Text Mercury Uptake by Desulfovibrio desulfuricans ND132: Passive or Active?
by An, Jing and Zhang, Lijie and Lu, Xia and Pelletier, Dale A and Pierce, Eric M and Johs, Alexander and Parks, Jerry M and Gu, Baohua and Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Environmental Science and Technology, ISSN 0013-936X, 06/2019, Volume 53, Issue 11, pp. 6264 - 6272
Recent studies have identified HgcAB proteins as being responsible for mercury [Hg(II)] methylation by certain anaerobic microorganisms. However, it remains... 
Sulfate reduction | Anaerobic microorganisms | Thiols | Deactivation | Bioavailability | Metabolism | Inactivation | Mercury compounds | Proteins | Spheroplasts | Uptakes | Microorganisms | Heat exchange | Desulfovibrio | Methylation | Mercury | Mercury (metal) | Carbonyls | Index Medicus | ENVIRONMENTAL SCIENCES
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12. Full Text Gene therapy: AAV2 gene therapy readministration in three adults with congenital blindness
by Bennett, Jean and Ashtari, Manzar and Wellman, Jennifer and Marshall, Kathleen A and Cyckowski, Laura L and Chung, Daniel C and McCague, Sarah and Pierce, Eric A and Chen, Yifeng and Bennicelli, Jeannette L and Zhu, Xiaosong and Ying, Gui-Shuang and Sun, Junwei and Wright, J. Fraser and Auricchio, Alberto and Simonelli, Francesca and Shindler, Kenneth S and Mingozzi, Federico and High, Katherine A and Maguire, Albert M
Science Translational Medicine, ISSN 1946-6234, 02/2012, Volume 4, Issue 120
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13. Full Text COPYRIGHT, PRESERVATION, AND ARCHIVES: An Interview with Eric Schwartz
by DAVID PIERCE and Eric Schwartz
The Moving Image: The Journal of the Association of Moving Image Archivists, ISSN 1532-3978, 10/2009, Volume 9, Issue 2, pp. 105 - 148
Eric Schwartz, a copyright attorney who is a partner at Mitchell, Silberberg & Knupp LLP, is interviewed in detail on the current copyright scene. Topics... 
Copyright laws | Motion picture industry | Archival preservation | Copyrights | Fair use | Libraries | Movies | Archives | Film preservation | Film archives | Copyright | Motion picture film | Schwartz, Eric | Preservation | Interviews | film preservation | copyright | film | dramatic arts | interview
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14. Full Text Comparative analysis of RNA-Seq alignment algorithms and the RNA-Seq unified mapper (RUM)
by Grant, Gregory R and Farkas, Michael H and Pizarro, Angel D and Lahens, Nicholas F and Schug, Jonathan and Brunk, Brian P and Stoeckert, Christian J and Hogenesch, John B and Pierce, Eric A
Bioinformatics, ISSN 1367-4803, 09/2011, Volume 27, Issue 18, pp. 2518 - 2528
Motivation: A critical task in high-throughput sequencing is aligning millions of short reads to a reference genome. Alignment is especially complicated for... 
SPLICE JUNCTIONS | COMPLEX | HUMAN GENOME | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | QUANTIFICATION | ULTRAFAST | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | SHORT READ ALIGNMENT | TOOL | REVEALS | Gene Library | Exons | Molecular Sequence Data | Benchmarking | RNA - genetics | Sequence Analysis, RNA - methods | RNA Splicing | Sequence Alignment | Algorithms | Animals | Base Sequence | High-Throughput Nucleotide Sequencing | Mice | Models, Genetic | Software | Genome | Cluster Analysis | Index Medicus | Original Papers
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15. Full Text A local complement response by RPE causes early-stage macular degeneration
by Fernandez-Godino, Rosario and Garland, Donita L and Pierce, Eric A
Human Molecular Genetics, ISSN 0964-6906, 10/2015, Volume 24, Issue 19, pp. 5555 - 5569
Inherited and age-related macular degenerations (AMDs) are important causes of vision loss. An early hallmark of these disorders is the formation of... 
DRUSEN FORMATION | CELLS | IN-VITRO | METALLOPROTEINASE ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | NONLETHAL OXIDANT INJURY | EXTRACELLULAR-MATRIX | ABERRANT ACCUMULATION | MALATTIA LEVENTINESE | HUMAN BRUCHS MEMBRANE | RETINAL-PIGMENT EPITHELIUM | Macular Degeneration - immunology | Extracellular Matrix Proteins - genetics | Cells, Cultured | Complement C5a - metabolism | Extracellular Matrix - metabolism | Animals | Macular Degeneration - genetics | Retinal Pigment Epithelium - immunology | Mice | Matrix Metalloproteinases - metabolism | Mutation | Complement C3a - metabolism | Extracellular Matrix Proteins - metabolism | Disease Models, Animal | Macular Degeneration - pathology | Index Medicus | Original
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