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Chemical Science, ISSN 2041-6520, 4/2015, Volume 6, Issue 5, pp. 266 - 2686
The synergistic action of light, oxygen and a photosensitizer (PS) has found applications for decades in medicine under the name of photodynamic therapy (PDT)... 
Names | Chemotherapy | Photodynamic therapy | Toxicity | Medical services | Strategy | Tumors | Cancer
Journal Article
Chemical Science, ISSN 2041-6520, 05/2015, Volume 6, Issue 5, pp. 2660 - 2686
The synergistic action of light, oxygen and a photosensitizer (PS) has found applications for decades in medicine under the name of photodynamic therapy (PDT)... 
POLYPYRIDYL COMPLEXES | DNA PHOTOCLEAVAGE | PLATINUM COMPLEX | PHOTODYNAMIC THERAPY | POTENTIAL APPLICATION | RUTHENIUM-PORPHYRIN | BIOLOGICAL-ACTIVITIES | ANTICANCER COMPLEXES | CHEMISTRY, MULTIDISCIPLINARY | METAL-COMPLEXES | CELLULAR UPTAKE | Chemistry
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 10/2014, Volume 20, Issue 44, pp. 14421 - 14436
Six substitutionally inert [RuII(bipy)2dppz]2+ derivatives (bipy=2,2′‐bipyridine, dppz=dipyrido[3,2‐a:2′,3′‐c]phenazine) bearing different functional groups on... 
density functional calculations | singlet oxygen | fluorescence microscopy | photodynamic therapy | DNA binding | Density functional calculations | Photodynamic therapy | Singlet oxygen | Fluorescence microscopy | Fluorescence | Photochemotherapy | DNA-ligand interactions | DNA | Cervical cancer | Cancer
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 07/2017, Volume 23, Issue 41, pp. 9888 - 9896
Two [Ru(phen)2dppz]2+ derivatives (phen=1,10‐phenantroline, dppz=dipyrido[3,2‐a:2′,3′‐c]phenazine) with different functional groups on the dppz ligand... 
ruthenium | cancer | photosensitizers | medicinal inorganic chemistry | photodynamic therapy | CELLS | ORGANOMETALLIC RHENIUM COMPLEXES | CHEMISTRY, MULTIDISCIPLINARY | CELLULAR UPTAKE | LIGHT-SWITCH | IN-VITRO | DNA | BIOLOGICAL EVALUATION | SINGLET OXYGEN | ABSORPTION | METAL-COMPLEXES | Photosensitizing Agents - chemistry | Humans | Molecular Conformation | Crystallography, X-Ray | Spheroids, Cellular - cytology | Photochemotherapy | Ruthenium - chemistry | Singlet Oxygen - metabolism | Light | Spheroids, Cellular - drug effects | Coordination Complexes - toxicity | Photosensitizing Agents - chemical synthesis | Cell Survival - drug effects | Spheroids, Cellular - metabolism | Photons | Coordination Complexes - chemistry | Coordination Complexes - blood | Microscopy, Confocal | Singlet Oxygen - chemistry | Photosensitizing Agents - blood | Photosensitizing Agents - toxicity | Coordination Complexes - chemical synthesis | Hydrophobic and Hydrophilic Interactions | Organometallic Compounds - chemistry | HeLa Cells | Nitriles | Ruthenium | Analysis | Cancer | Photodynamic therapy | Radiation | Confocal microscopy | Confocal | Spheroids | Ruthenium compounds | Anticancer properties | Lipophilic | Phenazine | Singlet oxygen | Microscopy | Acetonitrile | Monolayers | Phototoxicity | Irradiation | Antitumor activity | Ligands | Phosphorescence | Localization | Functional groups | Index Medicus
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 12/2012, Volume 134, Issue 50, pp. 20376 - 20387
A great majority of the Ru complexes currently studied in anticancer research exert their antiproliferative activity, at least partially, through ligand... 
POLYPYRIDYL COMPLEXES | RU(II) COMPLEX | APOPTOSIS | DNA-BINDING | IN-VITRO | LIGHT SWITCH | ANTICANCER COMPOUNDS | DPPZ COMPLEXES | ANTITUMOR-ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | METAL-COMPLEXES | Reactive oxygen species | Ligand binding (Biochemistry) | Ruthenium | Cancer cells | Physiological aspects | Carboxylic acids | Chemical properties | Research
Journal Article
Dalton Transactions, ISSN 1477-9226, 2013, Volume 43, Issue 11, pp. 4287 - 4294
Over the recent years, several Re(I) organometallic compounds have been shown to be toxic to various cancer cell lines. However, these compounds lacked... 
Index Medicus
Journal Article
Chemical Science, ISSN 2041-6520, 08/2016, Volume 7, Issue 9, pp. 6115 - 6124
Photodynamic therapy (PDT) is an attractive, complementary medical technique to chemotherapy. Among the different photosensitizers (PSs) employed, Ru(ii)... 
Chemotherapy | Inhibitors | Cell death | Interphase | Deoxyribonucleic acid | Irradiation | Nuclei (cytology) | Nuclei
Journal Article
Journal Article
Chemical Science, ISSN 2041-6520, 2016, Volume 7, Issue 9, pp. 6115 - 6124
Journal Article
European Journal of Inorganic Chemistry, ISSN 1434-1948, 08/2015, Volume 2015, Issue 23, pp. 3879 - 3891
Photoactivated chemotherapy (PACT) relies on the use of a drug and light to cause cell death. Unlike photodynamic therapy (PDT), its mechanism of action is... 
Medicinal chemistry | Antitumor agents | Ruthenium | Photoactivated chemotherapy | Peptides | Neuropeptides | Chemotherapy | Cancer
Journal Article