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CANCERS, ISSN 2072-6694, 08/2019, Volume 11, Issue 8, p. 1176
The introduction of v-raf murine sarcoma viral oncogene homolog B (BRAF) inhibitors in melanoma patients with BRAF (V600E) mutations has demonstrated... 
NEGATIVE-FEEDBACK-REGULATION | KINASE PATHWAY | ADVANCED SOLID TUMORS | ACQUIRED-RESISTANCE | RAF KINASE | melanoma | BRAF | MITF | AUTOPHAGY | resistance | adaptive responses | ONCOLOGY | PHASE-I TRIAL | UP-REGULATION | ERK
Journal Article
EMBO Reports, ISSN 1469-221X, 05/2017, Volume 18, Issue 5, p. 797
The amplitude of transforming growth factor-[beta] (TGF-[beta]) signal is tightly regulated to ensure appropriate physiological responses. As part of negative... 
Ubiquitin | Transcription | Pathogenesis | Brain cancer | Transforming growth factor-b | Glioblastoma | Breast cancer | Feedback loops | Physiological responses | Recruitment | Degradation | Signal transduction | Negative feedback | Feedback | Smad2 protein | Biomarkers | Breast | Smad7 protein | Bioindicators | Growth factors | Ubiquitin-protein ligase | Cancer
Journal Article
Blood, ISSN 0006-4971, 08/2019
Oncogenic EZH2 is overexpressed and extensively involved in the pathophysiology of different cancers including extranodal natural killer/T-cell lymphoma... 
Journal Article
EMBO reports, ISSN 1469-221X, 05/2017, Volume 18, Issue 5, pp. 797 - 808
Journal Article
Molecular & Cellular Oncology, ISSN 2372-3556, 09/2018, Volume 5, Issue 5, p. e1497862
Response to targeted therapies is limited by the activation or inhibition of feedback loops. Here we report the ubiquitin specific peptidase 28/F-box WD... 
USP28/BRAF/Melanoma/Vemurafenib resistance
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 09/2019, Volume 10, Issue 1, pp. 1 - 19
Journal Article
Oncotarget, ISSN 1949-2553, 04/2018, Volume 9, Issue 28, pp. 20179 - 20212
Breast cancer is the second leading cause of cancer related deaths in women. It is therefore important to understand the mechanisms underlying breast cancer... 
XIST and HOTAIR | Breast cancer | Mammary gland development | Long non-coding RNA
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 07/2018, Volume 215, Issue 7, pp. 1913 - 1928
Journal Article
12/2018, Volume 23, Issue 6, 14
Prior to the sequencing of the human genome, it was presumed that most of the DNA coded for proteins. However, with the advent of next-generation sequencing,... 
lncRNA interactome | long noncoding RNA | tools for lncRNA functional annotation | CHEMISTRY, ANALYTICAL | BIOCHEMICAL RESEARCH METHODS | CROSS-LINKING | TRANSCRIPTOME-WIDE | CLIP-SEQ | DNA ELEMENTS | SECONDARY STRUCTURE | BINDING-SITES | GENOME-WIDE IDENTIFICATION | ANTISENSE OLIGONUCLEOTIDES | MOLECULAR-MECHANISMS | Review
Book Review
by Sirunyan, A.M and Tumasyan, A and Adam, W and Ambrogi, F and Asilar, E and Bergauer, T and Brandstetter, J and Brondolin, E and Dragicevic, M and Erö, J and Escalante Del Valle, A and Flechl, M and Friedl, M and Frühwirth, R and Ghete, V.M and Grossmann, J and Hrubec, J and Jeitler, M and König, A and Krammer, N and Krammer, M and Krätschmer, I and Liko, D and Madlener, T and Mikulec, I and Pree, E and Rad, N and Rohringer, H and Schieck, J and Schöfbeck, R and Spanring, M and Spitzbart, D and Waltenberger, W and Wittmann, J and Wulz, C.-E and Zarucki, M and Chekhovsky, V and Mossolov, V and Suarez Gonzalez, J and De Wolf, E.A and Di Croce, D and Janssen, X and Lauwers, J and Van De Klundert, M and Van Haevermaet, H and Van Mechelen, P and Van Remortel, N and Abu Zeid, S and Blekman, F and D'Hondt, J and De Bruyn, I and De Clercq, J and Deroover, K and Flouris, G and Lontkovskyi, D and Lowette, S and Marchesini, I and Moortgat, S and Moortgat, F and Moreels, L and Python, Q and Skovpen, K and Skovpen, Y and Tavernier, S and Van Doninck, W and Van Mulders, P and Van Parijs, I and Beghin, D and Bilin, B and Brun, H and Clerbaux, B and De Lentdecker, G and Delannoy, A.G and Delannoy, H and Dorney, B and Fasanella, D and Fasanella, G and Favart, L and Goldouzian, R and Grebenyuk, A and Kalsi, A.K and Lenzi, T and Lenzi, P and Luetic, J and Maerschalk, T and Marinov, A and Seva, T and Starling, E and Vander Velde, C and Vanlaer, P and Vannerom, D and Yonamine, R and Zenoni, F and Cornelis, T and Dobur, D and Fagot, A and Gul, M and Khvastunov, I and Poyraz, D and Roskas, C and ... and CMS Collaboration and Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States) and Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Physics Letters B, ISSN 0370-2693, 05/2018, Volume 780, Issue C, pp. 501 - 532
A search for the standard model (SM) Higgs boson (H) decaying to when produced in association with an electroweak vector boson is reported for the following... 
CMS | Higgs | Physics | PARTICLES | PHYSICS, NUCLEAR | MODEL | CROSS-SECTION | STRAHLUNG | BROKEN SYMMETRIES | ASTRONOMY & ASTROPHYSICS | HADRON | MASS | PROGRAM | PHYSICS, PARTICLES & FIELDS | Physics - High Energy Physics - Experiment | PHYSICS OF ELEMENTARY PARTICLES AND FIELDS
Journal Article