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Pharmaceutical Research, ISSN 0724-8741, 12/2017, Volume 34, Issue 12, pp. 2637 - 2651
The accumulation of the neurotoxin beta-amyloid (Aβ) is a major hallmark in Alzheimer’s disease (AD). Aβ homeostasis in the brain is governed by its production... 
Biochemistry, general | blood-brain barrier | LRP1 | drug delivery | choroid plexus | Biomedical Engineering | beta-amyloid | targeting | Biomedicine | Pharmacy | angiopeps | Medical Law | Pharmacology/Toxicology | Alzheimer's disease
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 10/2019, Volume 56, Issue 10, p. 7234
The low-density lipoprotein receptor-related protein-1 (LRP1) has a dual role in the metabolism of the amyloid precursor protein (APP). In cellular models,... 
Analysis | Low density lipoproteins | Amyloid beta-protein | Mice | Models | Alzheimer's disease
Journal Article
Neuroforum, ISSN 0947-0875, 11/2018, Volume 24, Issue 4, pp. 297 - 304
Journal Article
Neuroforum, ISSN 0947-0875, 11/2018, Volume 24, Issue 4, pp. A197 - A205
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 12/2017, Volume 34, Issue 12, pp. 2637 - 2651
The accumulation of the neurotoxin beta-amyloid (Aβ) is a major hallmark in Alzheimer’s disease (AD). Aβ homeostasis in the brain is governed by its production... 
Drug delivery systems | Blood-brain barrier | Neurodegenerative diseases | Medical treatment | Blood vessels | Homeostasis | β-Amyloid | Receptor density | Drug delivery | Alzheimers disease | Alzheimer's disease | Low density lipoprotein
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P361 - P362
Journal Article
Experimental Cell Research, ISSN 0014-4827, 01/2016, Volume 340, Issue 1, p. 102
  The low density lipoprotein receptor-related protein 1 (LRP1) has been shown to interact with [beta]1-integrin and regulate its surface expression. LRP1... 
Physiological aspects | Analysis | Integrins | Proteins | Cellular biology | Rodents | Cell adhesion & migration
Journal Article
Experimental Brain Research, ISSN 0014-4819, 04/2012, Volume 217, Issue 3-4, p. 325
  Issue Title: Special Issue on The physiological functions of the β-amyloid precursor protein APP 
Physiological aspects | Development and progression | Genetic aspects | Research | Alzheimer's disease | Amyloid beta-protein
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e32568
Journal Article
Journal Article
Frontiers in Molecular Neuroscience, ISSN 1662-5099, 01/2017, Volume 9, p. 159
The membrane bound metalloprotease meprin beta is important for collagen fibril assembly in connective tissue formation and for the detachment of the... 
APP | Shedding | N-terminal truncated Aβ | Proteolysis | Meprin β | HUMAN CEREBROSPINAL-FLUID | shedding | N-terminal truncated A beta | AMYLOID PRECURSOR PROTEIN | NEUROSCIENCES | INFLAMMATORY-BOWEL-DISEASE | meprin beta | WILD-TYPE MICE | IN-VIVO | A-BETA | FAMILIAL ALZHEIMERS-DISEASE | PLAQUE-FORMATION | proteolysis | CATHEPSIN-B | TRANSGENIC MICE
Journal Article
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