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Lancet Oncology, The, ISSN 1470-2045, 2010, Volume 11, Issue 11, pp. 1036 - 1047
Summary Background High-dose methotrexate is the standard of care for patients with newly diagnosed primary CNS lymphoma. The role of whole brain radiotherapy... 
Hematology, Oncology and Palliative Medicine | DEFERRED RADIOTHERAPY | 1ST-LINE TREATMENT | ONCOLOGY-GROUP | COMBINED-MODALITY THERAPY | ONCOLOGY | CONSOLIDATION RADIOTHERAPY | CELL TRANSPLANTATION | INITIAL TREATMENT | CENTRAL-NERVOUS-SYSTEM | CEREBROSPINAL-FLUID | CHEMOTHERAPY | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Lymphoma - mortality | Antimetabolites, Antineoplastic - administration & dosage | Central Nervous System Neoplasms - radiotherapy | Lymphoma - drug therapy | Time Factors | Dose Fractionation | Female | Lymphoma - radiotherapy | Radiotherapy, Adjuvant | Risk Assessment | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Survival Rate | Treatment Outcome | Chi-Square Distribution | Cranial Irradiation - adverse effects | Cytarabine - administration & dosage | Disease-Free Survival | Methotrexate - adverse effects | Ifosfamide - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Antimetabolites, Antineoplastic - adverse effects | Methotrexate - administration & dosage | Aged | Central Nervous System Neoplasms - drug therapy | Central Nervous System Neoplasms - mortality | Germany | Chemotherapy | Radiation | Product development | Lymphomas | Methotrexate | Radiotherapy | Biometry | Cancer
Journal Article
Science, ISSN 0036-8075, 09/2013, Volume 341, Issue 6151, pp. 1257 - 1257
Cancer is a highly complex disease that can encompass multiple genomic alterations in the progression from normal to diseased cell. Recent studies point to the... 
Progressions | Biomarkers | Genetics | Evolution | Aberration | Monitoring | Tumors | Cancer
Journal Article
Science, ISSN 0036-8075, 09/2013, Volume 341, Issue 6151, pp. 1257 - 1257
Cancer is a highly complex disease that can encompass multiple genomic alterations in the progression from normal to diseased cell. Recent studies point to the... 
Journal Article
Journal Article
International Journal of Cancer, ISSN 0020-7136, 09/2012, Volume 131, Issue 6, pp. 1342 - 1350
Journal Article
Journal Article
Brain, ISSN 0006-8950, 10/2007, Volume 130, Issue 10, pp. 2596 - 2606
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2014, Volume 15, Issue 10, pp. 1100 - 1108
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 12/2009, Volume 27, Issue 35, pp. 5874 - 5880
Purpose The standard of care for anaplastic gliomas is surgery followed by radiotherapy. The NOA-04 phase III trial compared efficacy and safety of... 
MALIGNANT GLIOMA | SURVIVAL | ONCOLOGY | GLIOBLASTOMA-MULTIFORME | EUROPEAN ORGANIZATION | MGMT GENE | OLIGODENDROGLIAL TUMORS | RADIOTHERAPY | CHEMOTHERAPY | BRAIN-TUMORS | 1P/19Q LOSS | Procarbazine - administration & dosage | Dacarbazine - adverse effects | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Lomustine - adverse effects | Middle Aged | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Antineoplastic Agents, Alkylating - administration & dosage | Glioma - radiotherapy | Glioma - genetics | Young Adult | DNA Methylation | Time Factors | Radiotherapy, Adjuvant - adverse effects | Glioma - pathology | Treatment Failure | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Vincristine - administration & dosage | Adult | Female | Brain Neoplasms - mortality | Chemotherapy, Adjuvant | Brain Neoplasms - radiotherapy | Promoter Regions, Genetic | Dacarbazine - administration & dosage | Glioma - mortality | Drug Administration Schedule | Risk Assessment | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Brain Neoplasms - drug therapy | Disease Progression | Disease-Free Survival | DNA Modification Methylases - genetics | Procarbazine - adverse effects | Vincristine - adverse effects | Aged | Mutation | Antineoplastic Agents, Alkylating - adverse effects | Lomustine - administration & dosage | Glioma - drug therapy | Index Medicus
Journal Article
by Torchia, Jonathon, MSc and Picard, Daniel, MSc and Lafay-Cousin, Lucie, MD and Hawkins, Cynthia E, PhD and Kim, Seung-Ki, MD and Letourneau, Louis, BSc and Ra, Young-Shin, Prof and Ho, King Ching, MSc and Chan, Tiffany Sin Yu, PhD and Sin-Chan, Patrick, MSc and Dunham, Christopher P, MD and Yip, Stephen, FRCPC and Ng, Ho-keung, MD and Lu, Jian-Qiang, FRCPC and Albrecht, Steffen, MD and Pimentel, José, PhD and Chan, Jennifer A, MD and Somers, Gino R, MBBS and Zielenska, Maria, PhD and Faria, Claudia C, PhD and Roque, Lucia, PhD and Baskin, Berivan, PhD and Birks, Diane, MS and Foreman, Nick, Prof and Strother, Douglas, MD and Klekner, Almos, PhD and Garami, Miklos, PhD and Hauser, Peter, PhD and Hortobágyi, Tibor, PhD and Bognár, Laszló, PhD and Wilson, Beverly, MD and Hukin, Juliette, FRCPC and Carret, Anne-Sophie, MD and Van Meter, Timothy E, PhD and Nakamura, Hideo, MD and Toledano, Helen, MD and Fried, Iris, MD and Fults, Daniel, MD and Wataya, Takafumi, PhD and Fryer, Chris, FRCPC and Eisenstat, David D, MD and Scheineman, Katrin, Prof and Johnston, Donna, MD and Michaud, Jean, MD and Zelcer, Shayna, MD and Hammond, Robert, MD and Ramsay, David A, MBChB and Fleming, Adam J, MD and Lulla, Rishi R, MD and Fangusaro, Jason R, MD and Sirachainan, Nongnuch, MD and Larbcharoensub, Noppadol, MD and Hongeng, Suradej, MD and Barakzai, Muhammad Abrar, MD and Montpetit, Alexandre, PhD and Stephens, Derek, MSc and Grundy, Richard G, FRCPCH and Schüller, Ulrich, MD and Nicolaides, Theodore, MD and Tihan, Tarik, PhD and Phillips, Joanna, PhD and Taylor, Michael D, PhD and Rutka, James T, MD and Dirks, Peter, PhD and Bader, Gary D, PhD and Warmuth-Metz, Monika, Prof and Rutkowski, Stefan, Prof and Pietsch, Torsten, Prof and Judkins, Alexander R, MD and Jabado, Nada, PhD and Bouffet, Eric, Prof and Huang, Annie, Dr and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet and Medicinsk genetik och genomik
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 5, pp. 569 - 582
Journal Article
Acta neuropathologica, ISSN 0001-6322, 2012, Volume 123, Issue 4, pp. 473 - 484
Medulloblastoma is the most common malignant brain tumor in childhood. Molecular studies from several groups around the world demonstrated that medulloblastoma... 
Pathology | Neurosciences | Medicine & Public Health | Medulloblastoma | Pediatric brain tumor | Subgroups | Meta-analysis | PROFILES | SUBTYPES | DISTINCT | PATHOLOGY | NEUROSCIENCES | ADULT | CLINICAL NEUROLOGY | PEDIATRIC MEDULLOBLASTOMAS | BETA-CATENIN STATUS | CHILDHOOD MEDULLOBLASTOMA | Multivariate Analysis | Meta-Analysis as Topic | Age Distribution | Kv1.1 Potassium Channel - metabolism | Cerebellar Neoplasms - diagnosis | Humans | Transcriptome | Child, Preschool | Hedgehog Proteins - metabolism | Male | Gene Expression Profiling | Wnt Proteins - metabolism | Young Adult | Chromosomes, Human, Pair 3 | Wnt Proteins - genetics | Hedgehog Proteins - genetics | Microarray Analysis | Adult | Female | Retrospective Studies | Cerebellar Neoplasms - classification | Medulloblastoma - genetics | Child | Gene Expression Regulation, Neoplastic - physiology | Kv1.1 Potassium Channel - genetics | Receptors, Atrial Natriuretic Factor - metabolism | Medulloblastoma - diagnosis | International Cooperation | Cerebellar Neoplasms - genetics | Chromosomes, Human, Pair 17 | Adolescent | Chromosome Aberrations | Survival Analysis | Cytogenetics | Receptors, Atrial Natriuretic Factor - genetics | Medulloblastoma - classification | Cohort Studies | Immunohistochemistry | Demography | Wnt protein | Brain tumors | Data processing | Single-nucleotide polymorphism | Gene expression | Survival | Reviews | Hedgehog protein | DNA | Children | Original Paper
Journal Article