X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (10) 10
humans (9) 9
cell line, tumor (6) 6
activation (4) 4
cd16 (4) 4
lymphoma (4) 4
lymphoma, mantle-cell - genetics (4) 4
oncology (4) 4
animals (3) 3
b cells (3) 3
cell biology (3) 3
cytotoxicity (3) 3
immunology (3) 3
leukemia (3) 3
lymphomas (3) 3
mantle cell lymphoma (3) 3
mice (3) 3
mutation (3) 3
obinutuzumab (3) 3
phosphorylation (3) 3
rituximab (3) 3
antigen receptors (2) 2
antigens (2) 2
cell survival (2) 2
cells, cultured (2) 2
chronic lymphocytic-leukemia (2) 2
cytokines (2) 2
cytomegalovirus-infection (2) 2
enzyme inhibitors - pharmacology (2) 2
enzymes (2) 2
expression (2) 2
gene (2) 2
genomes (2) 2
hemic and lymphatic diseases (2) 2
immunoglobulin (2) 2
immunoglobulin heavy chains - genetics (2) 2
immunoglobulins (2) 2
killer cells, natural - drug effects (2) 2
killer cells, natural - immunology (2) 2
kinases (2) 2
leukemia, lymphocytic, chronic, b-cell - genetics (2) 2
leukemia, lymphocytic, chronic, b-cell - pathology (2) 2
lymphocytes (2) 2
lymphoma, mantle-cell - pathology (2) 2
map kinase (2) 2
medicine (2) 2
monoclonal antibodies (2) 2
multidisciplinary sciences (2) 2
mutations (2) 2
natural killer cells (2) 2
natural-killer-cells (2) 2
nk cells (2) 2
opsonization (2) 2
original (2) 2
original research (2) 2
pathology (2) 2
phosphatidylinositol (2) 2
phosphatidylinositol 3-kinases - metabolism (2) 2
phosphoproteins - metabolism (2) 2
protein (2) 2
proteins (2) 2
purines - pharmacology (2) 2
quinazolinones - pharmacology (2) 2
research (2) 2
rna (2) 2
tumors (2) 2
1-phosphatidylinositol 3-kinase (1) 1
actin polymerization (1) 1
acute lymphoblastic-leukemia (1) 1
acute myeloid-leukemia (1) 1
adaptor proteins, signal transducing - metabolism (1) 1
adcc (1) 1
adcc; fc glycoengineering; fcγriiia/cd16; ifnγ; nk cells; obinutuzumab; immunology and allergy; immunology; oncology (1) 1
adoptive immunotherapy (1) 1
agammaglobulinaemia tyrosine kinase (1) 1
aid (1) 1
algorithms (1) 1
alk (1) 1
amino acid sequence (1) 1
anaplastic large-cell lymphoma (1) 1
anaplastic lymphoma kinase - metabolism (1) 1
anti-cd20 monoclonal-antibody (1) 1
antibodies (1) 1
antibodies, monoclonal - pharmacology (1) 1
antibodies, monoclonal - therapeutic use (1) 1
antibodies, monoclonal, humanized - pharmacology (1) 1
antibody (1) 1
antibody-dependent cell cytotoxicity - drug effects (1) 1
antidepressants (1) 1
antineoplastic agents - adverse effects (1) 1
antineoplastic agents - pharmacology (1) 1
antineoplastic agents, immunological - pharmacology (1) 1
article subject (1) 1
authorship (1) 1
b cell activation (1) 1
b-cell lymphoma (1) 1
b-cell receptor (1) 1
b-cells (1) 1
b-lymphocytes - drug effects (1) 1
b-lymphocytes - enzymology (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature medicine, ISSN 1546-170X, 2018, Volume 25, Issue 1, pp. 130 - 140
In T lymphocytes, the Wiskott-Aldrich Syndrome protein (WASP) and WASP-interacting-protein (WIP) regulate T cell antigen receptor (TCR) signaling, but their... 
ALK | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | ACTIN POLYMERIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | RHOA | DEFICIENCY | CELL BIOLOGY | CDC42 | MUTATIONS | RAC1 | WIP | Wiskott-Aldrich Syndrome Protein - deficiency | Cell Proliferation | Humans | cdc42 GTP-Binding Protein - metabolism | Guanosine Triphosphate - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Lymphoma, T-Cell - metabolism | MAP Kinase Signaling System | Lymphoma, T-Cell - enzymology | Wiskott-Aldrich Syndrome Protein - metabolism | Anaplastic Lymphoma Kinase - metabolism | Cytoskeletal Proteins - metabolism | STAT3 Transcription Factor - metabolism | Tumor Suppressor Proteins - metabolism | Cell Survival | Down-Regulation | Kaplan-Meier Estimate | CCAAT-Enhancer-Binding Protein-beta - metabolism | Animals | Lymphoma, T-Cell - pathology | Cell Line, Tumor | Protein Binding | T-Lymphocytes - immunology | Mice | Enzyme Activation | Research | B cells | T cells | Protein kinases | Cdc42 protein | GTP | Stat3 protein | MAP kinase | Lymphocytes T | CCAAT/enhancer-binding protein | Kinases | Lymphoma | Suppressors | Proteins | T-cell receptor | Inhibitors | Clonal deletion | Protein kinase | Lymphocytes | Tumor suppressor genes | Lymphomas | Anaplastic large-cell lymphoma | Protein-tyrosine kinase | T-cell lymphoma | Tumors
Journal Article
Nature (London), ISSN 1476-4687, 2017, Volume 542, Issue 7642, pp. 489 - 493
Activation-induced cytidine deaminase (AID) is a B-cell-specific enzyme that targets immunoglobulin genes to initiate class switch recombination and somatic... 
SUPER-ENHANCERS | INDUCED CYTIDINE DEAMINASE | DNA | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | IBRUTINIB | CLASS-SWITCH RECOMBINATION | MECHANISMS | TARGETING BTK | AID | SEQUENCING REVEALS | Isoquinolines - adverse effects | Class I Phosphatidylinositol 3-Kinases - metabolism | Humans | Lymphoma, Mantle-Cell - pathology | Phosphatidylinositol 3-Kinases - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Translocation, Genetic - drug effects | Isoquinolines - pharmacology | Antineoplastic Agents - adverse effects | Genomic Instability - drug effects | Female | Antineoplastic Agents - pharmacology | Purines - adverse effects | B-Lymphocytes - pathology | Immunoglobulin Class Switching - drug effects | Somatic Hypermutation, Immunoglobulin - drug effects | Lymphoma, Mantle-Cell - genetics | B-Lymphocytes - metabolism | Quinazolinones - pharmacology | Pyrazoles - adverse effects | Pyrazoles - pharmacology | Enzyme Inhibitors - adverse effects | B-Lymphocytes - enzymology | Purines - pharmacology | Enzyme Inhibitors - pharmacology | Pyrimidines - pharmacology | Class I Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | B-Lymphocytes - drug effects | Animals | Agammaglobulinaemia Tyrosine Kinase | Cytidine Deaminase - metabolism | Pyrimidines - adverse effects | Cell Line, Tumor | Mice | Immunoglobulin Heavy Chains - genetics | Quinazolinones - adverse effects | Recombination, Genetic - drug effects | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
Oncoimmunology, ISSN 2162-402X, 2017, Volume 6, Issue 3, p. e1290037
Natural killer (NK) cell-mediated antibody-dependent cellular cytotoxicity (ADCC), based on the recognition of IgG-opsonized targets by the low-affinity... 
IFNγ | NK cells | Fc glycoengineering | ADCC | FcγRIIIA/CD16 | obinutuzumab | NATURAL-KILLER-CELLS | ACTIVATION | IFN gamma | THERAPEUTIC ANTIBODIES | LYMPHOMA PATIENTS | CYTOKINE | IMMUNOLOGY | RECEPTOR 3A GENOTYPE | Fc gamma RIIIA/CD16 | ANTI-CD20 MONOCLONAL-ANTIBODY | ONCOLOGY | RITUXIMAB | CD16 | CYTOTOXICITY | fcγriiia/cd16 | ifnγ | adcc | nk cells | fc glycoengineering
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 07/2019, Volume 28, Issue 5, pp. 1307 - 1322.e8
CD40 has major roles in B cell development, activation, and germinal center responses. CD40 hypoactivity causes immunodeficiency whereas its overexpression... 
humoral immunity | ESCRT | N6-Methyladenosine | MAP kinase | CRISPR screen | NF-kappaB | immunodeficiency | germinal center | B cell activation | TNF receptor superfamily | INACTIVATION | TRANSCRIPTS | METHYLATION | PROTEIN | GENE | MECHANISM | ROLES | GERMINAL-CENTERS | EXPRESSION | BINDING | CELL BIOLOGY | Life Sciences
Journal Article
Journal Article
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, p. 489
...Author(s): Mara Compagno [1]; Qi Wang [1]; Chiara Pighi [1]; Taek-Chin Cheong [1]; Fei-Long Meng [2]; Teresa Poggio [3]; Leng-Siew Yeap [2]; Elif Karaca [1... 
Physiological aspects | Phosphatidylinositol | B cells | Proteins | Cell growth | Genomes | Mutation | RNA polymerase | Kinases | Deoxyribonucleic acid--DNA
Journal Article
Cellular Oncology, ISSN 2211-3428, 4/2011, Volume 34, Issue 2, pp. 141 - 153
Journal Article
Cancer immunology, immunotherapy, ISSN 1432-0851, 2020, Volume 69, Issue 4, pp. 501 - 512
... by defucosylated tumor‑targeting mAb sensitizes human NK cells to γc cytokine stimulation via PI3K/mTOR axis Cristina Capuano1 · Chiara Pighi1 · Roberta Maggio1,6 · Simone... 
Gene Expression - drug effects | TOR Serine-Threonine Kinases - metabolism | Humans | Phosphatidylinositol 3-Kinases - metabolism | Interferon-gamma - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Receptors, IgG - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Antibodies, Monoclonal, Humanized - pharmacology | Interferon-gamma - genetics | Quinazolinones - pharmacology | Interleukin-12 - pharmacology | Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases - metabolism | Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases - genetics | Purines - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Sirolimus - pharmacology | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Antineoplastic Agents, Immunological - pharmacology | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Cell Line, Tumor | Killer Cells, Natural - drug effects | MicroRNAs - genetics | Killer Cells, Natural - metabolism | TOR protein | myo-Inositol-1 (or 4)-monophosphatase | Post-transcription | Inositol | Phosphorylation | Chronic lymphatic leukemia | Cytokines | Phosphatidylinositol 3,4,5-triphosphate | Immunoregulation | Opsonization | Gene regulation | Rituximab | Rapamycin | Interleukin 15 | Lymphoma | 1-Phosphatidylinositol 3-kinase | Phosphatidylinositol | CD16 antigen | Interleukin 2 | γ-Interferon | Monoclonal antibodies | CD20 antigen | miRNA | Natural killer cells | IFN-γ | Obinutuzumab | PI3K | miR-155 | mTOR | CD16 | Original
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3
...Author(s): Giulia Paciello [sup.1]*, Andrea Acquaviva [sup.1], Chiara Pighi [sup.2] [sup.3], Alberto Ferrarini [sup.4], Enrico Macii [sup.1], Alberto Zamo... 
Enzymes | Immunoglobulins | Employee motivation | Lymphomas | B cells | RNA
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 164 - 164
Abstract Activation-induced cytidine deaminase (AID) is a B cell-specific enzyme that initiates class switch recombination (CSR) and somatic hypermutation... 
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 3673 - 3673
Abstract INTRODUCTION: We recently described inactivating mutations of the FBXO11 gene in Diffuse Large B Cell Lymphoma (DLBCL). One major function of FBXO11... 
Journal Article