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1813
eBook
PL o S Genetics (Online), ISSN 1553-7390, 03/2015, Volume 11, Issue 3, p. e1005035
Journal Article
by Peters, Marjolein and Joehanes, Roby and Pilling, Luke and Schurmann, Claudia and Conneely, Karen N and Powell, Joseph and Reinmaa, Eva and Sutphin, George L and Zhernakova, Alexana and Schramm, Katharina and Wilson, Yana A and Kobes, Sayuko and Tukiainen, Taru and Ramos, Yolande and Göring, Harald H and Fornage, Myriam and Liu, Yongmei and Gharib, Sina and Stranger, Barbara and Jager, Philip and Aviv, Abraham and Levy, Daniel and Murabito, Joanne and Munson, Peter J and Huan, Tianxiao and Hofman, Albert and Uitterlinden, Ané and Rivadeneira Ramirez, Fernando and van Rooij, Jeroen and Stolk, Lisette and Broer, Linda and Verbiest, Michael and Jhamai, Mila and Arp, Pascal and Metspalu, Anes and Tserel, Liina and Milani, Lili and Samani, Nilesh and Peterson, Pärt and Kasela, Silva and Codd, Veryan and Peters, Annette and Ward-Caviness, Cavin K and Herder, Christian and Waldenberger, Melanie and Roden, Michael and Singmann, Paula and Zeilinger, Sonja and Illig, Thomas and Homuth, Georg and Grabe, Hans Jörgen and Völzke, Henry and Steil, Leif and Kocher, Thomas and Murray, Anna and Melzer, David and Yaghootkar, Hanieh and Bandinelli, S and Moses, Eric and Kent, Jack and Curran, Joanne and Johnson, Matthew and Williams-Blangero, Sarah and Westra, Harm-Jan and McRae, Allan F and Smith, Jennifer A and Kardia, Sharon and Hovatta, Iiris and Perola, Markus and Ripatti, Samuli and Salomaa, Veikko and Henders, Anjali and Martin, Nicholas and Smith, Alicia K and Mehta, Divya and Binder, Elisabeth B and Nylocks, K. Maria and Kennedy, Elizabeth M and Klengel, Torsten and Ding, Jingzhong and Suchy-Dicey, Astrid and Enquobahrie, D and Brody, Jennifer and Rotter, Jerome I and Chen, Yii-Der I and Houwing-Duistermaat, Jeanine and Kloppenburg, Margreet and Slagboom, Eline and Helmer, Quinta and Hollander, Wouter and Bean, Shannon and Raj, Towfique and Bakhshi, Noman and Wang, Qiao Ping and Oyston, Lisa J and Psaty, Bruce and Tracy, Russell and Montgomery, Grant and Turner, Stephen and Blangero, John and ... and NABEC UKBEC Consortium and NABEC/UKBEC Consortium
Nature Communications, ISSN 2041-1723, 10/2015, Volume 6, Issue 1, p. 8570
textabstractDisease incidences increase with age, but the molecular characteristics of ageing that lead to increased disease susceptibility remain inadequately... 
LIFE-SPAN | OXIDATIVE STRESS | METHYLATION | PROFILES | GLYCOSAMINOGLYCANS | HUMAN LONGEVITY | DROSOPHILA-MELANOGASTER | MULTIDISCIPLINARY SCIENCES | PATTERNS | GENE-EXPRESSION CHANGES | GENOME-WIDE ASSOCIATION | Aging - blood | DNA Methylation | Humans | Transcriptome | European Continental Ancestry Group | Gene Expression Profiling | Biomarkers - blood
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2018, Volume 13, Issue 9, p. e0203504
Higher Red Blood Cell Distribution Width (RDW or anisocytosis) predicts incident coronary artery disease (CAD) plus all-cause and cardiovascular mortality, but... 
MORTALITY | POPULATION | OLDER-ADULTS | MULTIDISCIPLINARY SCIENCES | RISK | DEATH | UNSELECTED OUTPATIENTS | LARGE COHORT | ASSOCIATION | Leukemia - blood | Follow-Up Studies | Humans | Middle Aged | Erythrocyte Indices | Male | Survival Rate | Cardiovascular Diseases - pathology | Healthy Volunteers | Biomarkers, Tumor - blood | Disease-Free Survival | Time Factors | Models, Biological | Cardiovascular Diseases - blood | Adult | Female | Aged | Leukemia - mortality | Medical research | Wellness programs | Analysis | Mortality | Patient outcomes | Medicine, Experimental | United Kingdom | Blood cell count | Coronary heart disease | Health care | Heart | Heart attacks | Leukemia | Colorectal carcinoma | Medical records | Cardiovascular disease | Systematic review | Medical diagnosis | Epidemiology | Blood | Skin cancer | Vascular diseases | Red blood cells | Fibrillation | Hemoglobin | Aging | Population | Chronic obstructive pulmonary disease | Heart diseases | Volunteers | Public health | Hypertension | Stroke | Hematology | Anemia | Diabetes mellitus | Melanoma | Coronary artery | Health risks | Assessment centers | Dose-response effects | Hazards | Genetic diversity | Angina pectoris | Coronary artery disease | Hospitals | Medical prognosis | Coronary vessels | Skin | Internet | Cell size | Cardiovascular diseases | Electronic health records | Elderly | Smoking | Cancer
Journal Article
Lancet, The, ISSN 0140-6736, 2014, Volume 384, Issue 9938, pp. 153 - 163
Journal Article
Journal Article
Clinical Science, ISSN 0143-5221, 2018, Volume 132, Issue 3, pp. 313 - 325
Coronary heart disease (CHD) is a leading cause of morbidity in people over 65 years of age; >40% of all deaths are due to this condition. The association... 
Journal Article
Aging, ISSN 1945-4589, 01/2016, Volume 8, Issue 9, pp. 1844 - 1865
textabstractEstimates of biological age based on DNA methylation patterns, often referred to as "epigenetic age", "DNAm age", have been shown to be robust... 
DNA methylation | Epigenetics | All-cause mortality | Epigenetic clock | Lifespan | Mortality | lifespan | CANCER | epigenetics | CELL BIOLOGY | all-cause mortality | DISEASE | mortality | COHORT | EPIDEMIOLOGY | BRAIN | epigenetic clock | BLOOD | LIFE
Journal Article
by Joehanes, Roby and Just, A.C and Marioni, Riccardo and Pilling, Luke and Reynolds, Lindsay and Mandaviya, P.R and Guan, Weihua and Xu, T and Elks, Cathy and Aslibekyan, S and Moreno-Macías, Hortensia and Smith, Jennifer A and Brody, Jennifer and Dhingra, R and Yousefi, Paul and Pankow, James and Kunze, S and Shah, S.H and McRae, Allan F and Lohman, Kurt and Sha, J and Absher, Devin and Ferrucci, Luigi and Zhao, W and Demerath, Ellen and Bressler, Jan and Grove, Megan and Huan, Tianxiao and Liu, Chunyu and Mendelson, M.M and Yao, Chen and Kiel, Douglas P and Peters, Annette and Wang-Sattler, Rui and Visscher, Peter and Wray, Naomi and Starr, John and Ding, J and Roiguez, C.J and Wareham, Nick and Irvin, M.R and Zhi, D and Barrdahl, Myrto and Vineis, Paolo and Ambatipudi, S and Uitterlinden, Ané and Hofman, Albert and Schwartz, J and Colicino, E and Hou, L and Vokonas, P.S and Hernandez, Dena and Singleton, Anew and Bandinelli, Stefania and Turner, Stephen and Ware, Erin B and Smith, A.K and Klengel, Torsten and Binder, Elisabeth B and Psaty, Bruce and Taylor, Kent and Gharib, Sina and Swenson, B.R and Liang, L and Demeo, Dawn L and O'Connor, George and Herceg, Zdenko and Ressler, K.J and Conneely, Karen N and Sotoodehnia, Nona and Kardia, S.L.R and Melzer, David and Baccarelli, Anea A and Meurs, Joyce and Romieu, Isabelle and Arnett, Donna and Ong, K.K and Liu, Yongmei and Waldenberger, Melanie and Deary, Ian J and Fornage, Myriam and Levy, Daniel and London, Stephanie J
Circulation: Cardiovascular Genetics, ISSN 1942-325X, 10/2016, Volume 9, Issue 5, pp. 436 - 447
Journal Article
BMJ (Online), ISSN 0959-8146, 2019, Volume 364, p. k5222
OBJECTIVE To compare prevalent and incident morbidity and mortality between those with the HFE p.C282Y genetic variant (responsible for most hereditary... 
REPLACEMENT | POPULATION | PENETRANCE | MEDICINE, GENERAL & INTERNAL | DENSITY-LIPOPROTEIN CHOLESTEROL | HFE C282Y HOMOZYGOSITY | INCREASED RISK | IRON-OVERLOAD | DISEASE | PREVALENCE | MUTATIONS
Journal Article
The Journals of Gerontology: Series A, ISSN 1079-5006, 02/2019, Volume 74, Issue 3, pp. 350 - 357
Abstract Background Individuals with low cardiovascular risk factor profiles experience lower rates of cardiovascular diseases, but associations with geriatric... 
DEMENTIA | OLDER-ADULTS | VALIDATION | FOLLOW-UP | PREVALENCE | Chronic pain | GERIATRICS & GERONTOLOGY | OBESITY | Cardiovascular risk | DISEASE | GERONTOLOGY | Frailty | Incontinence | HEALTH | Healthy aging | Medical Sciences | The Journal of Gerontology
Journal Article
by Ligthart, Symen and Marzi, C and Aslibekyan, S and Mendelson, M.M and Conneely, Karen N and Tanaka, Toshiko and Colicino, E and Waite, Lindsay and Joehanes, Roby and Guan, Weihua and Brody, Jennifer and Elks, Cathy and Marioni, Riccardo and Jhun, Min A and Agha, G and Bressler, Jan and Ward-Caviness, Cavin K and Chen, Brian and Huan, Tianxiao and Bakulski, Kelly M and Salfati, Elias and Fiorito, G and Wahl, Simone and Schramm, Katharina and Sha, J and Hernandez, Dena and Just, A.C and Smith, Jennifer A and Sotoodehnia, Nona and Pilling, Luke and Pankow, James and Tsao, P.S and Liu, C and Zhao, Wei and Guarrera, Simonetta and Michopoulos, V.J and Smith, A.K and Peters, Marjolein and Melzer, David and Vokonas, P and Fornage, Myriam and Prokisch, Holger and Bis, Joshua and Chu, Auey and Herder, Christian and Grallert, Harald and Yao, Chen and Shah, Sonia and McRae, Allan F and Lin, H and Horvath, Steve and Fallin, D and Hofman, Albert and Wareham, Nick and Wiggins, Kerri and Feinberg, Anew P and Starr, John and Visscher, Peter and Murabito, Joanne and Kardia, S.L.R and Absher, Devin and Binder, Elisabeth and Singleton, Anew and Bandinelli, Stefania and Peters, Annette and Waldenberger, Melanie and Matullo, G and Schwartz, J.D and Demerath, Ellen and Uitterlinden, Ané and Meurs, J.B.J and Franco, Oscar and Chen, Y and Levy, Daniel and Turner, Stephen and Deary, Ian J and Ressler, Kerry and Dupuis, Josée and Ferrucci, Luigi and Ong, K.K and Assimes, Themistocles and Boerwinkle, Eric and Koenig, Wolfgang and Arnett, Donna and Baccarelli, Anea A and Benjamin, Emelia and Dehghan, Abbas and CHARGE Epigenetics Coronary Heart and WHI-EMPC Invest Giovanni Fiorito and CHARGE epigenetics of Coronary Heart Disease and WHI-EMPC Investigators
Genome Biology, ISSN 1474-7596, 12/2016, Volume 17, Issue 1, p. 255
Journal Article