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Cold Spring Harbor Protocols, ISSN 1940-3402, 02/2014, Volume 2014, Issue 2, pp. 178 - 181
Resistance to targeted therapies has emerged as a major hurdle for the successful use of drugs in the clinic. Therefore, understanding the underlying molecular... 
Dose-Response Relationship, Drug | Lung Neoplasms - drug therapy | Protein Kinase Inhibitors - administration & dosage | Animals | Protein Kinase Inhibitors - therapeutic use | Lung Neoplasms - pathology | Mice | Protein Kinase Inhibitors - pharmacology | Drug Resistance, Neoplasm - drug effects
Journal Article
Cancer Discovery, ISSN 2159-8274, 10/2012, Volume 2, Issue 10, pp. 922 - 933
EGFR-mutant lung cancers eventually become resistant to treatment with EGFR tyrosine kinase inhibitors (TKIs). The combination of EGFR-TKI afatinib and... 
lung cancer | EGFR tyrosine kinase inhibitors | afatinib | EGFR mutations | erlotinib | HER2 amplification | cetuximab | EGFR T790M | acquired resistance
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 11/2019, Volume 116, Issue 45, pp. 22730 - 22736
Journal Article
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 07/2016, Volume 16, Issue 2, pp. 457 - 471
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2014, Volume 111, Issue 1, pp. 11 - 11
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2014, Volume 111, Issue 1, p. E6
  All cellular proteins are derived from preexisting ones by natural selection. Because of the random nature of this process, many potentially useful protein... 
Proteins | Rodents | Genetics | Amino acids | Evolution | Biochemistry | Hydrophobic surfaces
Journal Article
Cancer Discovery, ISSN 2159-8274, 2013, Volume 3, Issue 2, pp. 168 - 181
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 933 - 933
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. LB-309 - LB-309
Journal Article
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