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Chemical Reviews, ISSN 0009-2665, 10/2016, Volume 116, Issue 20, p. 12785
  Tyrosine-type site-specific recombinases (T-SSRs) have opened new avenues for the predictable modification of genomes as they enable precise genome editing... 
Enzymes | Eukaryotes | Yeast | Genetics | Genomes | Deoxyribonucleic acid--DNA
Journal Article
Journal of Chemical Information and Modeling, ISSN 1549-9596, 01/2015, Volume 55, Issue 1, p. 114
  Glycosaminoglycans (GAGs) represent a class of anionic periodic linear polysaccharides, which mediate cell communication processes by interactions with their... 
Proteins | Carbohydrates | Molecules | Simulation | Cells
Journal Article
ISSN 2041-6520, 1/2019, Volume 1, Issue 3, pp. 866 - 878
Binding of sulfated glycosaminoglycans (GAG) to a wide spectrum of extracellular regulatory proteins is crucial for physiological processes such as cell... 
Journal Article
Journal Article
Journal of Chemical Information and Modeling, ISSN 1549-9596, 02/2014, Volume 54, Issue 2, p. 582
  We present Dynamic Molecular Docking (DMD), a novel targeted molecular dynamics-based protocol developed to address ligand and receptor flexibility as well... 
Proteins | Molecules | Solvents | Ligands | Electrostatics | Chemokines
Journal Article
Journal Article
Journal of Chemical Theory and Computation, ISSN 1549-9618, 07/2015, Volume 11, Issue 8, pp. 3906 - 3918
Journal Article
Nature Biotechnology, ISSN 1087-0156, 04/2016, Volume 34, Issue 4, pp. 401 - 409
Journal Article
Scientific Reports, ISSN 2045-2322, 07/2016, Volume 6, Issue 1, p. 30130
Precise genome engineering is instrumental for biomedical research and holds great promise for future therapeutic applications. Site-specific recombinases... 
TARGET | MANIPULATION | GENE | DNA | MULTIDISCIPLINARY SCIENCES | SYNAPSE | CRE RECOMBINASE | GENERATION | EXCISION | PROMOTER | DIRECTED EVOLUTION | DNA - genetics | Genetic Engineering - methods | Animals | Humans | Genome - genetics | Plasmids - genetics | Recombination, Genetic - genetics | DNA Nucleotidyltransferases - genetics | Tyrosine - genetics
Journal Article
Glycoconjugate Journal, ISSN 0282-0080, 06/2017, Volume 34, Issue 3, pp. 427 - 440
Glycosaminoglycans (GAGs) exhibit a key role in cellular communication processes through interactions with target proteins of the extracellular matrix (ECM).... 
FGF | Site-mapping | MM-GBSA | Molecular dynamics | Docking | Heparin | GAG | BIOCHEMISTRY & MOLECULAR BIOLOGY | FIBROBLAST-GROWTH-FACTOR | INTERLEUKIN-8 | NMR | FORCE-FIELD | ANTITHROMBIN | HEPARAN-SULFATE PROTEOGLYCANS | BINDING-SITES | PROTEINS | GLYCOSAMINOGLYCAN | Carbohydrate Sequence | Protein Conformation, alpha-Helical | Heparin - metabolism | Humans | Fibroblast Growth Factor 1 - metabolism | Crystallography, X-Ray | Molecular Dynamics Simulation | Amino Acid Motifs | Thermodynamics | Protein Conformation, beta-Strand | Sulfates - chemistry | Fibroblast Growth Factor 1 - chemistry | Protein Binding | Molecular Docking Simulation | Protein Interaction Domains and Motifs | Binding Sites | Heparin - chemistry | Fibroblast growth factors | Anticoagulants (Medicine) | Glycosaminoglycans | Analysis | Computers | Fibroblast growth factor | Electrochemical machining | Series (mathematics) | Mapping | Cell interactions | Flexibility | Dynamical systems | Molecular docking | Proteins | Cellular communication | Mathematical analysis | Extracellular matrix | Mathematical models | Sampling | Heparan sulfate | Evaluation | Fibroblast growth factor 1 | Experimental data | Computer simulation | Macromolecules | Pattern recognition | Derivatives | Peptide mapping | Free energy | Sensitivity | Computer applications | Protein interaction | Protein structure | System effectiveness | Original
Journal Article
Cell Stem Cell, ISSN 1934-5909, 05/2009, Volume 4, Issue 5, pp. 403 - 415
Journal Article