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Experimental dermatology, ISSN 0906-6705, 06/2019
Although several cytokines and chemokines have been investigated as possible mediators of fibrosis in Systemic Sclerosis (SSc), specific correlation between... 
Journal Article
Anti-Cancer Drugs, ISSN 0959-4973, 12/2017, Volume 29, Issue 2, pp. 157 - 166
Substitutions in thiophene structure give rise to new derivatives with different biological and pharmacological activities. The present study investigated the... 
Anticancer | Cell death | Three-dimensional culture | three-dimensional culture | cell death | INDUCED APOPTOSIS | PYRAN | CYCLE ARREST | MODEL | anticancer | CYTOTOXIC EVALUATION | INVASION | INHIBITION | ONCOLOGY | BIOLOGICAL EVALUATION | RESISTANCE | PHARMACOLOGY & PHARMACY | AGENTS
Journal Article
Scientia Medica, ISSN 1980-6108, 01/2016, Volume 26, Issue 3, p. ID23399
Objetivos: A osteoporose é uma doença comum, que afeta principalmente as mulheres e tem sido associada com o sistema imune. Este estudo objetivou avaliar... 
SAÚDE DA MULHER | OSTEOPOROSE PÓS-MENOPAUSA | GERONTOLOGIA | DENSIDADE ÓSSEA
Journal Article
Scientia Medica, ISSN 1980-6108, 01/2016, Volume 26, Issue 3, p. ID23399
Objetivos: A osteoporose é uma doença comum, que afeta principalmente as mulheres e tem sido associada com o sistema imune. Este estudo objetivou avaliar... 
SAÚDE DA MULHER | OSTEOPOROSE PÓS-MENOPAUSA | GERONTOLOGIA | DENSIDADE ÓSSEA
Journal Article
Journal Article
Autoimmune Diseases, ISSN 2090-0422, 07/2019, Volume 2019, pp. 1 - 7
Background. Due to the variety of functions that galectins (Gal) possess, it is clear that they participate in the pathogenesis of rheumatoid arthritis (RA).... 
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2017, Volume 815, pp. 210 - 218
The mechanisms and antinociceptive effects of a novel α adrenoceptor agonist, 3-(2-chloro-6-fluorobenzil)-imidazolinide-2,4-dione (PT-31) were investigated... 
PT-31 | α2A adrenoceptors | Clonidine | Acute and chronic pain | Locus coeruleus | α | adrenoceptors | Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2017, Volume 815, p. 210
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.ejphar.2017.09.018 The... 
Medical colleges | Care and treatment | Pain | Analysis | Formaldehyde | Chronic pain
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2016, Volume 791, pp. 622 - 631
Journal Article
Natural Product Research, ISSN 1478-6419, 2018, pp. 1 - 10
Betulin (BE) is a pentacyclic triterpenes, obtained from natural sources and with several biological activities described, such as anti-tumoral and... 
derivatives | cytokines | Betulin | cytotoxicity | cyclooxygenase-2
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2016, Volume 791, p. 622
Atherosclerosis is a complex disorder with a multifactorial pathogenesis. We previously indicated that the new TZD LPSF/GQ-02 inhibits hepatic steatosis and... 
Drug therapy | Inflammation | Atherosclerosis | RNA | Collagen
Journal Article
Journal of Rheumatology, ISSN 0315-162X, 11/2012, Volume 39, Issue 11, pp. 2221 - 2221
Journal Article
Drug Metabolism Letters, ISSN 1872-3128, 09/2016, Volume 10, Issue 3, pp. 206 - 212
Background: LPSF/GQ-02 is a promising benzylidene thiazolidinedione that has demonstrated antidiabetic, antidyslipidemic, anti-atherosclerotic properties and... 
LPSF/GQ-02 | UHPLC | Safety assessment | Preclinical pharmacokinetics | Thiazolidinedione | Bioanalytical method
Journal Article
Open Rheumatology Journal, ISSN 1874-3129, 2018, Volume 12, Issue 1, pp. 160 - 170
Rheumatoid Arthritis (RA) is a chronic and inflammatory disease that affects about 1% of the world's population. Almost 70% of RA patients have a... 
Systemic arterial hypertension | Therapy | Cardiovascular disease | Immunomodulatory effects | Cytokines | Rheumatology
Journal Article
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