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Neurotoxicology, ISSN 0161-813X, 03/2018, Volume 65, p. 248
The effect of sarin on the binding parameters (KD & Bmax) of M2 muscarinic acetylcholine receptor (mAChR) was studied 24 h and 1 week post exposure. Male &... 
Binding | Brain | Acetylcholine receptors (muscarinic) | Rats | Exposure | Males | Recovery | Neurology | Receptors | Reduction | Drunkenness | Sarin | Atropine | Brain damage | Affinity | Receptor density | Intoxication | Females | Synaptic cleft
Journal Article
Journal of Molecular Neuroscience, ISSN 0895-8696, 2003, Volume 20, Issue 3, pp. 349 - 356
Journal Article
Brain Research, ISSN 0006-8993, 04/2006, Volume 1085, Issue 1, pp. 102 - 110
Certain organophosphate (OP) cholinesterase inhibitors (ChEIs) are also known to bind to the muscarinic acetylcholine receptor (mAChR). The functional... 
cAMP metabolism | PI hydrolysis | Allosteric binding site | G proteins | Cholinesterase inhibitor | Organophosphate compound | Muscarinic acetylcholine receptor
Journal Article
Brain Research, ISSN 0006-8993, 04/2006, Volume 1085, Issue 1, p. 102
Certain organophosphate (OP) cholinesterase inhibitors (ChEIs) are also known to bind to the muscarinic acetylcholine receptor (mAChR). The functional... 
Coenzymes | Guanosine | Smart drugs and nutrients | Cyclic adenylic acid | Hamsters | Cholinesterase inhibitors | Cyclic guanylic acid | Membrane proteins | Hydrolysis | Carbachol | Physiological aspects | G proteins | Adenylic acid
Journal Article
Journal of Molecular Neuroscience, ISSN 0895-8696, 08/2002, Volume 19, Issue 1-2, pp. 145 - 153
The M-1 muscarinic agonists AF102B (Cevimeline, EVOXACTM: prescribed in USA and Japan for Sjogren's Syndrome), AF150(S) and AF267B-1) are neurotrophic and... 
Agonist | Memory | AF102B | AF150(S) | AF267B | Amyloid precursor protein | muscarinic | Tau protein | Cell death | Aged microcebes | Neurotrophic | β-amyloid | Alzheimer's | Apoptosis | ACTIVATION | memory | RECEPTOR AGONISTS | apoptosis | MICROCEBUS-MURINUS | CEREBROSPINAL-FLUID | TAU-PHOSPHORYLATION | beta-amyloid | amyloid precursor protein | BETA-PROTEIN | neurotrophic | CELLS | cell death | BIOCHEMISTRY & MOLECULAR BIOLOGY | agonist | aged microcebes | NEUROSCIENCES | CEREBRAL-CORTEX | M-1 muscarinic | SECRETION | tau protein | Water | Spinal Cord - drug effects | Spinal Cord - metabolism | Apoptosis - drug effects | Muscarinic Agonists - pharmacology | Muscarinic Agonists - therapeutic use | Amyloid beta-Peptides - drug effects | tau Proteins - metabolism | Receptors, Muscarinic - metabolism | Spiro Compounds - therapeutic use | Hippocampus - drug effects | Thiazoles - therapeutic use | PC12 Cells | Cerebral Cortex - metabolism | Receptors, Muscarinic - drug effects | Piperidines - pharmacology | Amyloid beta-Peptides - metabolism | Models, Animal | Cell Death - drug effects | Cerebral Cortex - drug effects | Phosphorylation - drug effects | Drug Evaluation, Preclinical | Nerve Growth Factor - metabolism | Alzheimer Disease - drug therapy | Rats | Epidermal Growth Factor - metabolism | Cognition - drug effects | Maze Learning - drug effects | Receptor, Muscarinic M1 | Hippocampus - metabolism | Animals | Piperidines - therapeutic use | Alzheimer Disease - metabolism | Mice | Thiazoles - pharmacology | Oxidative Stress - drug effects | Spiro Compounds - pharmacology | Drug therapy | Alzheimer's disease | Amyloid beta-protein | Care and treatment | Research | Health aspects | Agonists (Biochemistry) | Alzheimers disease | Rodents
Journal Article
Brain Research, ISSN 0006-8993, 2006, Volume 1085, Issue 1, pp. 102 - 110
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 11/1998, Volume 71, Issue 5, pp. 2094 - 2103
Journal Article
Developmental Brain Research, ISSN 0165-3806, 2003, Volume 144, Issue 1, pp. 83 - 90
We have recently cloned the novel homeobox-containing activity-dependent neuroprotective protein (ADNP). In the current study, mouse ADNP was shown to be... 
Activity-dependent neuroprotective protein | Embryo | Neural tube | Gene expression | Knockout | Vasoactive intestinal peptide | knockout | DEFECTS | VASOACTIVE-INTESTINAL-PEPTIDE | NEUROTROPHIC FACTOR | MOUSE | embryo | neural tube | RESTRICTION | NEUROSCIENCES | activity-dependent neuroprotective protein | vasoactive intestinal peptide | GROWTH | MICE | VIP | BLOCKADE | EXPRESSION | gene expression | Mice, Knockout - genetics | Octamer Transcription Factor-3 | Organ Culture Techniques - methods | Brain - embryology | Mice, Knockout - embryology | Embryo, Mammalian | Homeodomain Proteins - metabolism | Repressor Proteins | Molecular Sequence Data | Embryonic and Fetal Development | Mice, Knockout - metabolism | Brain - metabolism | DNA-Binding Proteins - metabolism | RNA, Messenger - biosynthesis | Time Factors | Vasoactive Intestinal Peptide - pharmacology | Gene Expression Regulation, Developmental | Reverse Transcriptase Polymerase Chain Reaction - methods | Cloning, Molecular | In Situ Hybridization - methods | RNA, Messenger - drug effects | Blotting, Western - methods | Nerve Tissue Proteins - physiology | Paired Box Transcription Factors | Mice, Inbred C57BL | PAX6 Transcription Factor | Gestational Age | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Blotting, Northern - methods | Mice | Transcription Factors | Eye Proteins
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2000, Volume 21, pp. 187 - 187
Journal Article
Journal of Molecular Neuroscience, ISSN 0895-8696, 8/2003, Volume 20, Issue 3, pp. 349 - 356
M1 muscarinic receptors (M1 mAChRs) play a role in an apparent linkage of three major hallmarks of Alzheimer’s disease (AD): β-amyloid (Aβ) peptide; tau... 
Neurology | Neurosciences | α-APPs | animal models | Biomedicine | tau proteins | Alzheimer’s disease | cell death | M 1 agonist | apoptosis | β-amyloid
Journal Article
Journal of Molecular Neuroscience, ISSN 0895-8696, 8/2002, Volume 19, Issue 1, pp. 145 - 153
The M1 muscarinic agonists AF102B (Cevimeline, EVOXACTM: prescribed in USA and Japan for Sjogren’s Syndrome), AF150(S) and AF267B—1) are neurotrophic and... 
neurotrophic | Neurosciences | memory | cell death | AF102B | AF150(S) | AF267B | apoptosis | agonist | aged microcebes | M 1 muscarinic | Alzheimer’s | Neurology | Biomedicine | amyloid precursor protein | tau protein | β-amyloid
Journal Article
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