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British Journal of Pharmacology, ISSN 0007-1188, 02/2019
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 2019
Histamine dysregulation was implicated as a rare cause of Tourette syndrome and other tic disorders a decade ago by a landmark genetic study in a high density... 
Journal Article
American Academy of Child and Adolescent Psychiatry. Journal, ISSN 0890-8567, 10/2016, Volume 55, Issue 10, pp. S317 - S317
Objectives: TD and related tic disorders remain enigmatic, and their pathophysiology remains obscure. Pathophysiologically grounded animal models will be... 
Journal Article
Journal of the American Academy of Child & Adolescent Psychiatry, ISSN 0890-8567, 2016, Volume 55, Issue 10, pp. S317 - S317
Objectives: TD and related tic disorders remain enigmatic, and their pathophysiology remains obscure. Pathophysiologically grounded animal models will be... 
Pediatrics | Psychiatry | Tourette's syndrome | Basal ganglia | Animal models | Pathophysiological aspects | Dopamine | Neurons | Psychotherapy | Biosynthesis | Hypothalamus | Histidine decarboxylase | Ganglia | Histamine | Pathology | Animals | Repetitive behaviour | Histidine | Lighting | Treatment methods | Physiological psychology | Disruption | Psychopathology | Tourette syndrome | Laboratory animals
Journal Article
by Anttila, Verneri and Bulik-Sullivan, Brendan and Finucane, Hilary K and Walters, Raymond K and Bras, Jose and Duncan, Laramie and Escott-Price, Valentina and Falcone, Guido J and Gormley, Padhraig and Malik, Rainer and Patsopoulos, Nikolaos A and Ripke, Stephan and Wei, Zhi and Yu, Dongmei and Lee, Phil H and Turley, Patrick and Grenier-Boley, Benjamin and Chouraki, Vincent and Kamatani, Yoichiro and Berr, Claudine and Letenneur, Luc and Hannequin, Didier and Amouyel, Philippe and Boland, Anne and Deleuze, Jean-François and Duron, Emmanuelle and Vardarajan, Badri N and Reitz, Christiane and Goate, Alison M and Huentelman, Matthew J and Ilyas Kamboh, M and Larson, Eric B and Rogaeva, Ekaterina and George-Hyslop, Peter St and Hakonarson, Hakon and Kukull, Walter A and Farrer, Lindsay A and Barnes, Lisa L and Beach, Thomas G and Yesim Demirci, F and Head, Elizabeth and Hulette, Christine M and Jicha, Gregory A and Kauwe, John S.K and Kaye, Jeffrey A and Leverenz, James B and Levey, Allan I and Lieberman, Andrew P and Pankratz, Vernon S and Poon, Wayne W and Quinn, Joseph F and Saykin, Andrew J and Schneider, Lon S and Smith, Amanda G and Sonnen, Joshua A and Stern, Robert A and Van Deerlin, Vivianna M and Van Eldik, Linda J and Harold, Denise and Russo, Giancarlo and Rubinsztein, David C and Bayer, Anthony and Tsolaki, Magda and Proitsi, Petra and Fox, Nick C and Hampel, Harald and Owen, Michael J and Mead, Simon and Passmore, Peter and Morgan, Kevin and Nöthen, Markus M and Rossor, Martin and Lupton, Michelle K and Hoffmann, Per and Kornhuber, Johannes and Lawlor, Brian and McQuillin, Andrew and Al-Chalabi, Ammar and Bis, Joshua C and Ruiz, Agustin and Boada, Mercè and Seshadri, Sudha and Beiser, Alexa and Rice, Kenneth and Van Der Lee, Sven J and De Jager, Philip L and Geschwind, Daniel H and Riemenschneider, Matthias and Riedel-Heller, Steffi and Rotter, Jerome I and Ransmayr, Gerhard and Hyman, Bradley T and Cruchaga, Carlos and Alegret, Montserrat and Winsvold, Bendik and Palta, Priit and Farh, Kai-How and Cuenca-Leon, Ester and Furlotte, Nicholas and Kurth, Tobias and ... and Brainstorm Consortium and The Brainstorm Consortium
Science, ISSN 0036-8075, 06/2018, Volume 360, Issue 6395, pp. 1313 - 1313
Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We... 
ANOREXIA-NERVOSA | POPULATION-BASED TWIN | DEFICIT HYPERACTIVITY DISORDER | LONG-TERM SURVIVAL | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | GENETIC CORRELATIONS | BODY-MASS INDEX | MAJOR DEPRESSIVE DISORDER | BIPOLAR DISORDER | GENOME-WIDE ASSOCIATION | Genetic Variation | Mental Disorders - genetics | Genome-Wide Association Study | Phenotype | Brain Diseases - classification | Quantitative Trait, Heritable | Brain Diseases - diagnosis | Humans | Mental Disorders - classification | Risk Factors | Brain Diseases - genetics | Mental Disorders - diagnosis | Anorexia | Disorders | Cognitive ability | Bipolar disorder | Posttraumatic stress disorder | Mental depression | Epidemiology | Risk factors | Consortia | Proteins | Ischemia | Etiology | Classification | Gilles de la Tourette syndrome | Alzheimer's disease | Neurological disorders | Neurodegenerative diseases | Comorbidity | Behavior disorders | Anorexia nervosa | Risk analysis | Patients | Neurological diseases | Correlation analysis | Heritability | Attention deficit disorder | Headache | Mental disorders | Medical services | Schizophrenia | Risk sharing | Genomes | Heterogeneity | Biological effects | Risk assessment | Stroke | Phenotypes | Migraine | Attention deficit hyperactivity disorder | Eating disorders | Personality | Genetic diversity | Statistics | Activity patterns | Crohn's Disease | Population (statistical) | Scaffolding | Diagnostic systems | Alzheimers disease | Life Sciences | Human health and pathology | Mental Disorders | Neurons and Cognition | Brain Diseases | Genetics
Journal Article
by Davis, Lea K and Yu, Dongmei and Keenan, Clare L and Gamazon, Eric R and Konkashbaev, Anuar I and Derks, Eske M and Neale, Benjamin M and Yang, Jian and Lee, S. Hong and Evans, Patrick and Barr, Cathy L and Bellodi, Laura and Benarroch, Fortu and Berrio, Gabriel Bedoya and Bienvenu, Oscar J and Bloch, Michael H and Blom, Rianne M and Bruun, Ruth D and Budman, Cathy L and Camarena, Beatriz and Campbell, Desmond and Cappi, Carolina and Cardona Silgado, Julio C and Cath, Danielle C and Cavallini, Maria C and Chavira, Denise A and Chouinard, Sylvain and Conti, David V and Cook, Edwin H and Coric, Vladimir and Cullen, Bernadette A and Deforce, Dieter and Delorme, Richard and Dion, Yves and Edlund, Christopher K and Egberts, Karin and Falkai, Peter and Fernandez, Thomas V and Gallagher, Patience J and Garrido, Helena and Geller, Daniel and Girard, Simon L and Grabe, Hans J and Grados, Marco A and Greenberg, Benjamin D and Gross-Tsur, Varda and Haddad, Stephen and Heiman, Gary A and Hemmings, Sian M. J and Hounie, Ana G and Illmann, Cornelia and Jankovic, Joseph and Jenike, Michael A and Kennedy, James L and King, Robert A and Kremeyer, Barbara and Kurlan, Roger and Lanzagorta, Nuria and Leboyer, Marion and Leckman, James F and Lennertz, Leonhard and Liu, Chunyu and Lochner, Christine and Lowe, Thomas L and Macciardi, Fabio and McCracken, James T and McGrath, Lauren M and Mesa Restrepo, Sana C and Moessner, Rainald and Morgan, Jubel and Muller, Heike and Murphy, Dennis L and Naarden, Allan L and Ochoa, William Cornejo and Ophoff, Roel A and Osiecki, Lisa and Pakstis, Anew J and Pato, Michele T and Pato, Carlos N and Piacentini, John and Pittenger, Christopher and Pollak, Yehuda and Rauch, Scott L and Renner, Tobias J and Reus, Victor I and Richter, Margaret A and Riddle, Mark A and Robertson, Mary M and Romero, Roxana and Rosàrio, Maria C and Rosenberg, David and Rouleau, Guy A and Ruhrmann, Stephan and Ruiz-Linares, Anes and Sampaio, Aline S and Samuels, Jack and Sandor, Paul and Sheppard, Brooke and Singer, Harvey S and Smit, Jan H and ...
PLoS genetics, ISSN 1553-7390, 2013, Volume 9, Issue 10, p. e1003864
Journal Article
Psychiatric Annals, ISSN 0048-5713, 06/2015, Volume 45, Issue 6, pp. 308 - 315
Established treatments for obsessive-compulsive disorder (OCD) are of benefit in approximately 3 of every 4 patients, but refractory disease remains... 
SEROTONIN REUPTAKE INHIBITORS | TRANSPORTER GENE SLC1A1 | ADD-ON | PSYCHIATRY | LAMOTRIGINE AUGMENTATION | DOUBLE-BLIND | D-CYCLOSERINE | N-ACETYLCYSTEINE | PLACEBO-CONTROLLED TRIAL | RILUZOLE AUGMENTATION | GENOME-WIDE ASSOCIATION
Journal Article