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2009, ISBN 9780470145593, xx, 349
J. Suso Platero is Director of Oncology Biomarkers at Centocor. Formerly, he was associate director of molecular pathology at Bristol-Myers Squibb. Dr. Platero... 
Pathology | Pharmacogenetics | Molecular Biology | methods | Drug Design | Drug development | Pathology, Molecular
Book
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 06/2017, Volume 16, Issue 6, pp. 1010 - 1020
Fibroblast growth factor (FGF) signaling plays critical roles in key biological processes ranging from embryogenesis to wound healing and has strong links to... 
BREAST-CANCER | GROWTH-FACTOR RECEPTOR | GENE FUSIONS | ACTIVATION | PROTEIN | AMPLIFICATION | SOLID TUMORS | ONCOLOGY | BRIVANIB ALANINATE | SIGNALING PATHWAY | GASTRIC-CANCER | Phosphorylation | Humans | Male | Antineoplastic Agents - administration & dosage | Molecular Targeted Therapy | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Lysosomes - metabolism | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Pyrazoles - pharmacokinetics | Disease Models, Animal | Pyrazoles - pharmacology | Protein Kinase Inhibitors - pharmacokinetics | Quinoxalines - pharmacokinetics | Quinoxalines - administration & dosage | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Drug Discovery | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Animals | Signal Transduction - drug effects | Cell Line, Tumor | Protein Binding | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Cell culture | Fibroblast growth factor | Kinases | Metastases | Anticancer properties | Angiogenesis | Embryogenesis | Alterations | Xenografts | Protein-tyrosine kinase | Controlled release | Tyrosine | Wound healing | Extracellular signal-regulated kinase | Pharmacology | Tumor cell lines | Biological activity | Embryonic growth stage | Signaling | Inhibitors | Antitumor activity | Sustained release | Tumors | Cancer | Fibroblast growth factor receptors
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1856 - 13
Bronchial premalignant lesions (PMLs) are precursors of lung squamous cell carcinoma, but have variable outcome, and we lack tools to identify and treat PMLs... 
LUNG-CANCER | CELLS | DIAGNOSTIC EVALUATION | EPITHELIUM | MECHANISM | PACKAGE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | DYSPLASIA | RESISTANCE | GENOMIC CLASSIFIER
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 08/2017, Volume 16, Issue 8, pp. 1717 - 1726
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 09/2017, Volume 23, Issue 17, pp. 5091 - 5100
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2000, Volume 97, Issue 2, pp. 716 - 721
Centromeres of most organisms are embedded within constitutive heterochromatin, the condensed regions of chromosomes that account for a large fraction of... 
Proteins | Yeasts | Biological Sciences | Heterochromatin | Drosophila | Centromeres | HeLa cells | Histones | Antibodies | Open reading frames | Chromosomes | LOCALIZATION | ACTIVATION | INSTABILITY | CHROMATIN | MULTIDISCIPLINARY SCIENCES | CELL-LINES | heterochromatin | CHROMOSOME | ALPHA-SATELLITE DNA | MITOTIC APPARATUS | centromeres | CENP-A | Cell research | Analysis | Genomes | Research | histone H2B | Cid protein
Journal Article
Journal Article
BMC Cell Biology, ISSN 1471-2121, 01/2008, Volume 9, p. 4
A crucial event in Prostate Cancer progression is the conversion from a hormone-sensitive to a hormone-refractory disease state. Correlating with this... 
Androgens | Physiological aspects | Genetic aspects | Research | Diagnosis | Gene expression | Prostate cancer
Journal Article
Molecular Cell, ISSN 1097-2765, 1999, Volume 4, Issue 6, pp. 995 - 1004
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2000, Volume 97, Issue 2, p. 716
  Centromeres of most organisms are embedded within constitutive heterochromatin, the condensed regions of chromosomes that account for a large fraction of... 
Proteins | Deoxyribonucleic acid | DNA | Genetics
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 03/1998, Volume 140, Issue 6, p. 1297
  We examined the heterochromatic binding of GAGA factor and proliferation disrupter (Prod) proteins during the cell cycle in Drosophila melanogaster and... 
Proteins | Cellular biology | Insects | Deoxyribonucleic acid | DNA | Genetics
Journal Article
Journal Article
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