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Biochemical Journal, ISSN 0264-6021, 11/2011, Volume 439, Issue 3, pp. 349 - 374
Journal Article
2015, First edition., Methods in cell biology, ISBN 9780128000793, Volume 126
Web Resource
2004, ISBN 0198508786, xxvii. 447
Lysosomal storage diseases are inherited metabolic disorders characterized by severe pathology, typically involving the brain. Although individually rare, they... 
Brain | Lysosomal storage diseases | Treatment | Metabolism | Disorders | neuroscience | Lysosomal storage disorders - Treatment
Book
Drugs, ISSN 0012-6667, 11/2003, Volume 63, Issue 22, pp. 2435 - 2435
Journal Article
Nature reviews. Drug discovery, 11/2017
Lysosomal storage disorders (LSDs) - designated as 'orphan' diseases - are inborn errors of metabolism caused by defects in genes that encode proteins involved... 
Journal Article
ChemMedChem, ISSN 1860-7179, 08/2019, Volume 14, Issue 16, pp. 1466 - 1466
The Front Cover depicts two horses (taken by the lead author J.S.) that look like they are “joined at the hips.” Although they look “connected,” each horse... 
antioxidant | Niemann–Pick | protein aggregation | deferasirox | iron complexes
Journal Article
2015, ISBN 9780128000793, 451
This new volume of Methods in Cell Biology looks at methods for lysosomes and lysosomal diseases. Chapters focus upon practical experimental protocols to guide... 
Lysosomes | Biology, life sciences | Lysosomal storage diseases
eBook
Journal of Cell Biology, ISSN 0021-9525, 11/2012, Volume 199, Issue 5, pp. 723 - 734
Journal Article
Journal Article
Cell Calcium, ISSN 0143-4160, 08/2011, Volume 50, Issue 2
Disrupted cellular Ca.sup.2+ signaling is believed to play a role in a number of human diseases including lysosomal storage diseases (LSD). LSDs are a group of... 
Proteins | Metabolism, Inborn errors of
Journal Article
Journal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, 01/2016, Volume 117, p. 276
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.jpba.2015.08.011... 
Urine | Metabolites | Analysis | Physiological aspects
Journal Article
Cell Calcium, ISSN 0143-4160, 2011, Volume 50, Issue 2, pp. 200 - 205
Abstract Disrupted cellular Ca2+ signaling is believed to play a role in a number of human diseases including lysosomal storage diseases (LSD). LSDs are a... 
Advanced Basic Science | Mucolipidosis type IV | NAADP | NPC1 | MLIV | Lysosomal calcium | Lysosomal storage disease | Niemann-Pick | PROTEIN-KINASE-C | MUCOLIPIDOSIS TYPE-IV | CATION CHANNEL | ACIDIC ORGANELLES | RELEASE CHANNEL | PLASMA-MEMBRANE | CELL BIOLOGY | SPHINGOLIPID METABOLISM | CALCIUM-RELEASE | CHEDIAK-HIGASHI-SYNDROME | 2-PORE CHANNELS
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2008, Volume 28, Issue 27, pp. 6926 - 6937
Macroautophagy, a major pathway for organelle and protein turnover, has been implicated in the neurodegeneration of Alzheimer's disease (AD). The basis for the... 
Neuroprotection | Neurotoxicity | Neuron | Storage | Neuropathology | Lysosome | Neuron death | Aging | Neuronal death | Alzheimer | Autophagy | Culture | NEURODEGENERATIVE DISEASE | RAT-LIVER | APOPTOSIS | autophagy | neuron | VINBLASTINE | storage | MACROAUTOPHAGY | MAMMALIAN-CELLS | NEUROSCIENCES | neuron death | TRANSPORT | neurotoxicity | culture | neuronal death | neuroprotection | MONITORING AUTOPHAGY | DEGRADATION | MICE | aging | lysosome | neuropathology | Protein Kinases - metabolism | Neurons - pathology | Microtubule-Associated Proteins - metabolism | Tubulin Modulators - pharmacology | Peptide Hydrolases - drug effects | Autophagy - physiology | Alzheimer Disease - pathology | Brain - metabolism | Lysosomes - metabolism | Neurons - ultrastructure | Neurites - ultrastructure | Brain - ultrastructure | Lysosomes - pathology | Phagosomes - ultrastructure | Neurons - metabolism | Peptide Hydrolases - metabolism | Animals, Newborn | Alzheimer Disease - physiopathology | Protein Kinases - drug effects | Phagosomes - metabolism | Cells, Cultured | Rats | Neurites - metabolism | Phagosomes - pathology | Rats, Sprague-Dawley | Lysosomes - ultrastructure | Neurites - pathology | Animals | Cathepsins - metabolism | Alzheimer Disease - metabolism | Brain - pathology | TOR Serine-Threonine Kinases | Vinblastine - pharmacology | Index Medicus | Aging [Ageing] | Neuron Death
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2008, Volume 14, Issue 11, pp. 1247 - 1255
Journal Article
Cell Calcium, ISSN 0143-4160, 2011, Volume 50, Issue 2, pp. 200 - 205
Disrupted cellular Ca signaling is believed to play a role in a number of human diseases including lysosomal storage diseases (LSD). LSDs are a group of ∼50... 
Mucolipidosis type IV | NAADP | NPC1 | MLIV | Lysosomal calcium | Lysosomal storage disease | Niemann-Pick
Journal Article
Journal Article
Angewandte Chemie, ISSN 0044-8249, 04/2016, Volume 128, Issue 16, p. 5142
  The majority of lysosomal enzymes are targeted to the lysosome by post-translational tagging with N-glycans terminating in mannose-6-phosphate (M6P)... 
Enzymes | Chemical synthesis
Journal Article
Journal Article