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1. Full Text Integrative Clinical Genomics of Advanced Prostate Cancer
by Robinson, Dan and Van Allen, Eliezer M and Wu, Yi-Mi and Schultz, Nikolaus and Lonigro, Robert J and Mosquera, Juan-Miguel and Montgomery, Bruce and Taplin, Mary-Ellen and Pritchard, Colin C and Attard, Gerhardt and Beltran, Himisha and Abida, Wassim and Bradley, Robert K and Vinson, Jake and Cao, Xuhong and Vats, Pankaj and Kunju, Lakshmi P and Hussain, Maha and Feng, Felix Y and Tomlins, Scott A and Cooney, Kathleen A and Smith, David C and Brennan, Christine and Siddiqui, Javed and Mehra, Rohit and Chen, Yu and Rathkopf, Dana E and Morris, Michael J and Solomon, Stephen B and Durack, Jeremy C and Reuter, Victor E and Gopalan, Anuradha and Gao, Jianjiong and Loda, Massimo and Lis, Rosina T and Bowden, Michaela and Balk, Stephen P and Gaviola, Glenn and Sougnez, Carrie and Gupta, Manaswi and Yu, Evan Y and Mostaghel, Elahe A and Cheng, Heather H and Mulcahy, Hyojeong and True, Lawrence D and Plymate, Stephen R and Dvinge, Heidi and Ferraldeschi, Roberta and Flohr, Penny and Miranda, Susana and Zafeiriou, Zafeiris and Tunariu, Nina and Mateo, Joaquin and Perez-Lopez, Raquel and Demichelis, Francesca and Robinson, Brian D and Schiffman, Marc and Nanus, David M and Tagawa, Scott T and Sigaras, Alexandros and Eng, Kenneth W and Elemento, Olivier and Sboner, Andrea and Heath, Elisabeth I and Scher, Howard I and Pienta, Kenneth J and Kantoff, Philip and de Bono, Johann S and Rubin, Mark A and Nelson, Peter S and Garraway, Levi A and Sawyers, Charles L and Chinnaiyan, Arul M
Cell (Cambridge), ISSN 0092-8674, 05/2015, Volume 161, Issue 5, pp. 1215 - 1228
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasm Metastasis - genetics | Neoplasm Metastasis - drug therapy | Neoplasm Metastasis - pathology | Humans | Gene Expression Profiling - methods | Male | Mutation | Prostatic Neoplasms, Castration-Resistant - drug therapy | Prostatic Neoplasms, Castration-Resistant - genetics | Prostatic Neoplasms, Castration-Resistant - pathology | Cohort Studies | Genetic research | Genetic aspects | Prostate cancer | Cancer | Index Medicus | precision oncology | transcriptome sequencing | whole exome sequencing | prostate cancer genomics
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2. Full Text Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: Induction of steroidogenesis and androgen receptor splice variants
by Mostaghel, Elahe A and Marck, Brett T and Plymate, Stephen R and Vessella, Robert L and Balk, Stephen and Matsumoto, Alvin M and Nelson, Peter S and Montgomery, R. Bruce
Clinical cancer research, ISSN 1078-0432, 09/2011, Volume 17, Issue 18, pp. 5913 - 5925
Life Sciences & Biomedicine | Oncology | Science & Technology | Tumors of the urinary system | Urinary tract. Prostate gland | Gynecology. Andrology. Obstetrics | Pharmacology. Drug treatments | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Antineoplastic agents | Male genital diseases | Tumors | Prostatic Neoplasms - metabolism | Steroid 17-alpha-Hydroxylase - antagonists & inhibitors | Humans | Male | Gene Expression Profiling | Androstenols - therapeutic use | Biosynthetic Pathways - genetics | Prostatic Neoplasms - genetics | Gene Expression Regulation, Neoplastic - drug effects | Prostatic Neoplasms - drug therapy | Dihydrotestosterone - metabolism | Disease Models, Animal | Androgens - secretion | Alternative Splicing - genetics | Androstenols - pharmacology | Androstenes | Mice, SCID | Prostatic Neoplasms - mortality | Orchiectomy | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Animals | Receptors, Androgen - genetics | Cell Proliferation - drug effects | Mice | Androgens - metabolism | Index Medicus | steroidogenesis | abiraterone | androgen receptor splice variant | castration resistant prostate cancer | CYP17A1
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3. Full Text Integrative Clinical Genomics of Advanced Prostate Cancer
by Robinson, Dan and Van Allen, Eliezer M and Wu, Yi-Mi and Schultz, Nikolaus and Lonigro, Robert J and Mosquera, Juan-Miguel and Montgomery, Bruce and Taplin, Mary-Ellen and Pritchard, Colin C and Attard, Gerhardt and Beltran, Himisha and Abida, Wassim and Bradley, Robert K and Vinson, Jake and Cao, Xuhong and Vats, Pankaj and Kunju, Lakshmi P and Hussain, Maha and Feng, Felix Y and Tomlins, Scott A and Cooney, Kathleen A and Smith, David C and Brennan, Christine and Siddiqui, Javed and Mehra, Rohit and Chen, Yu and Rathkopf, Dana E and Morris, Michael J and Solomon, Stephen B and Durack, Jeremy C and Reuter, Victor E and Gopalan, Anuradha and Gao, Jianjiong and Loda, Massimo and Lis, Rosina T and Bowden, Michaela and Balk, Stephen P and Gaviola, Glenn and Sougnez, Carrie and Gupta, Manaswi and Yu, Evan Y and Mostaghel, Elahe A and Cheng, Heather H and Mulcahy, Hyojeong and True, Lawrence D and Plymate, Stephen R and Dvinge, Heidi and Ferraldeschi, Roberta and Flohr, Penny and Miranda, Susana and Zafeiriou, Zafeiris and Tunariu, Nina and Mateo, Joaquin and Perez-Lopez, Raquel and Demichelis, Francesca and Robinson, Brian D and Sboner, Andrea and Schiffman, Marc and Nanus, David M and Tagawa, Scott T and Sigaras, Alexandros and Eng, Kenneth W and Elemento, Olivier and Heath, Elisabeth I and Scher, Howard I and Pienta, Kenneth J and Kantoff, Philip and de Bono, Johann S and Rubin, Mark A and Nelson, Peter S and Garraway, Levi A and Sawyers, Charles L and Chinnaiyan, Arul M
Cell (Cambridge), ISSN 0092-8674, 07/2015, Volume 162, Issue 2, pp. 454 - 454
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology
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4. Full Text Clinical significance of AR-V567Es in prostate cancer-letter
by Uo, Takuma and Plymate, Stephen R
Clinical cancer research, ISSN 1078-0432, 10/2019, Volume 25, Issue 19, pp. 6009 - 6009
Life Sciences & Biomedicine | Oncology | Science & Technology | Prostatic Neoplasms | Male | Taxoids | Humans | Neoplastic Cells, Circulating | Index Medicus
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5. Full Text Truncation and constitutive activation of the androgen receptor by diverse genomic rearrangements in prostate cancer
by Henzler, Christine and Li, Yingming and Yang, Rendong and McBride, Terri and Ho, Yeung and Sprenger, Cynthia and Liu, Gang and Coleman, Ilsa and Lakely, Bryce and Li, Rui and Ma, Shihong and Landman, Sean R and Kumar, Vipin and Hwang, Tae Hyun and Raj, Ganesh V and Higano, Celestia S and Morrissey, Colm and Nelson, Peter S and Plymate, Stephen R and Dehm, Scott M
Nature communications, ISSN 2041-1723, 11/2016, Volume 7, Issue 1, pp. 13668 - 13668
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | RNA, Messenger - genetics | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Exons - genetics | Male | Chromosomes, Human, Pair 11 - genetics | Gene Dosage | RNA, Messenger - metabolism | Prostatic Neoplasms, Castration-Resistant - genetics | Neoplasm Metastasis | Alleles | Cell Line, Tumor | Clone Cells | Gene Rearrangement - genetics | Genome, Human | Index Medicus
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6. Full Text Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
by Sun, Shihua and Sprenger, Cynthia C. T and Vessella, Robert L and Haugk, Kathleen and Soriano, Kathryn and Mostaghel, Elahe A and Page, Stephanie T and Coleman, Ilsa M and Nguyen, Holly M and Sun, Huiying and Nelson, Peter S and Plymate, Stephen R
The Journal of clinical investigation, ISSN 0021-9738, 08/2010, Volume 120, Issue 8, pp. 2715 - 2730
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Neoplasm Transplantation | Prostatic Neoplasms - pathology | Humans | Gene Expression Regulation, Neoplastic | Male | Transplantation, Heterologous | Orchiectomy | Prostatic Neoplasms - therapy | Neoplasm Metastasis | RNA Splicing | Animals | Prostatic Neoplasms - genetics | Receptors, Androgen - genetics | Androgen Antagonists - therapeutic use | Cell Line, Tumor | Mice | Hydroxamic Acids - pharmacology | Receptors, Androgen - physiology | Complications and side effects | Hormone receptors | Castration | Development and progression | Properties | Prostate cancer | Risk factors | Index Medicus | Abridged Index Medicus
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7. Full Text An androgen receptor N-terminal domain antagonist for treating prostate cancer
by Myung, Jae-Kyung and Banuelos, Carmen A and Fernandez, Javier Garcia and Mawji, Nasrin R and Wang, Jun and Tien, Amy H and Yang, Yu Chi and Tavakoli, Iran and Haile, Simon and Watt, Kate and McEwan, Iain J and Plymate, Stephen and Andersen, Raymond J and Sadar, Marianne D
The Journal of clinical investigation, ISSN 0021-9738, 07/2013, Volume 123, Issue 7, pp. 2948 - 2960
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Prostatic Neoplasms - metabolism | Stereoisomerism | Humans | Receptors, Androgen - metabolism | Transcriptional Activation - drug effects | Cercopithecus aethiops | Male | Androgen Receptor Antagonists - pharmacology | Benzhydryl Compounds - chemistry | Luciferases - genetics | Androgen Receptor Antagonists - chemistry | Receptors, Androgen - chemistry | Chlorohydrins - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Genes, Reporter | Prostatic Neoplasms - drug therapy | Protein Structure, Tertiary | Prostatic Neoplasms - pathology | Gene Expression | Antineoplastic Agents, Hormonal - pharmacology | Click Chemistry | Mice, SCID | Chlorohydrins - chemistry | Orchiectomy | Xenograft Model Antitumor Assays | Animals | Receptors, Androgen - genetics | Tumor Burden - drug effects | Protein Binding | Mice, Inbred NOD | Benzhydryl Compounds - pharmacology | Cell Proliferation - drug effects | Mice | Antineoplastic Agents, Hormonal - chemistry | COS Cells | Luciferases - biosynthesis | Antagonists (Biochemistry) | Care and treatment | Androgens | Physiological aspects | Prostate cancer | Health aspects | Methods | Cancer | Proteins | Medical research | Ligands | Kinases | Gene expression | Experiments | Drug dosages | Tumors | Index Medicus | Abridged Index Medicus
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8. Full Text Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer
by Sharp, Adam and Coleman, Ilsa and Yuan, Wei and Sprenger, Cynthia and Dolling, David and Rodrigues, Daniel Nava and Russo, Joshua W and Figueiredo, Ines and Bertan, Claudia and Seed, George and Riisnaes, Ruth and Uo, Takuma and Neeb, Antje and Welti, Jonathan and Morrissey, Colm and Carreira, Suzanne and Luo, Jun and Nelson, Peter S and Balk, Steven P and True, Lawrence D and De Bono, Johann S and Plymate, Stephen R
The Journal of clinical investigation, ISSN 0021-9738, 01/2019, Volume 129, Issue 1, pp. 192 - 208
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Alternative Splicing | Neoplasm Proteins - biosynthesis | Humans | Gene Expression Regulation, Neoplastic | Male | Prostatic Neoplasms, Castration-Resistant - drug therapy | Mice, SCID | Prostatic Neoplasms, Castration-Resistant - metabolism | Mice, Inbred ICR | Prostatic Neoplasms, Castration-Resistant - genetics | Prostatic Neoplasms, Castration-Resistant - pathology | Antineoplastic Agents, Immunological - pharmacology | Xenograft Model Antitumor Assays | Neoplasm Metastasis | Animals | Receptors, Androgen - genetics | Receptors, Androgen - biosynthesis | Cell Line, Tumor | Mice | Neoplasm Proteins - genetics | Cancer patients | Usage | Development and progression | Genetic aspects | Biology | Research | Diagnosis | Gene expression | Prostate cancer | Health aspects | Alternative splicing | Medical research | Splicing | Laboratories | Copy number | Prostate-specific antigen | Metastasis | Cancer therapies | Survival | Patients | Metastases | Proteins | Studies | Androgens | Chemotherapy | Castration | Cell cycle | Protein expression | Ligands | Acetic acid | Prostate | Index Medicus | Abridged Index Medicus
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9. Full Text Alternative splicing in prostate cancer
by Paschalis, Alec and Sharp, Adam and Welti, Jonathan C and Neeb, Antje and Raj, Ganesh V and Luo, Jun and Plymate, Stephen R and de Bono, Johann. S
Nature reviews. Clinical oncology, ISSN 1759-4774, 11/2018, Volume 15, Issue 11, pp. 663 - 675
Life Sciences & Biomedicine | Oncology | Science & Technology | Prostatic Neoplasms - pathology | Cell Proliferation - genetics | Spliceosomes - genetics | Alternative Splicing - genetics | Humans | Carcinogenesis - genetics | Male | DNA Repair - genetics | Disease Progression | Neoplasm Metastasis | Prostatic Neoplasms - genetics | Receptors, Androgen - genetics | Protein Isoforms - genetics | Cell proliferation | Alternative splicing | Androgens | Castration | Isoforms | Ligands | Radiation therapy | DNA repair | Prostate cancer | Patients | Prostate | Metastases | Index Medicus
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