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Journal Article
Hepatology, ISSN 0270-9139, 03/2014, Volume 59, Issue 3, pp. 974 - 985
Journal Article
Journal Article
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems, ISSN 0278-0070, 12/2017, Volume 36, Issue 12, pp. 2003 - 2016
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, pp. e0133782 - e0133782
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2011, Volume 17, Issue 10, pp. 3077 - 3088
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2007, Volume 104, Issue 24, pp. 10022 - 10027
Bisphosphonate drugs (e.g., Fosamax and Zometa) are thought to act primarily by inhibiting farnesyl diphosphate synthase (FPPS), resulting in decreased... 
Enzymes | Yeasts | Electronic structure | Molecular structure | Terpenoids | Diphosphonates | Ligands | Biosynthesis | Diphosphates | Binding sites | Undecaprenyl diphosphate synthase | Geranylgeranyl diphosphate synthase | X-ray structure | Cell wall | FARNESYL DIPHOSPHATE SYNTHASE | POTENTIAL ROUTE | INHIBITION | MECHANISM | ISOPRENOID BIOSYNTHESIS | STRUCTURAL BASIS | NITROGEN-CONTAINING BISPHOSPHONATES | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | GERANYLGERANYL PYROPHOSPHATE SYNTHASE | DRUGS | Diphosphates - metabolism | Polyisoprenyl Phosphates - chemistry | Sesquiterpenes - metabolism | Models, Chemical | Stereoisomerism | Alkyl and Aryl Transferases - antagonists & inhibitors | Substrate Specificity | Crystallography, X-Ray | Isoenzymes - chemistry | Isoenzymes - metabolism | Transferases - metabolism | Farnesyltranstransferase - antagonists & inhibitors | Molecular Structure | Transferases - antagonists & inhibitors | Diterpenes - metabolism | Binding Sites | Dimerization | Diterpenes - chemistry | Alkyl and Aryl Transferases - chemistry | Sesquiterpenes - chemistry | Protein Structure, Secondary | Models, Molecular | Transferases - chemistry | Diphosphonates - metabolism | Polyisoprenyl Phosphates - metabolism | Farnesyltranstransferase - chemistry | Diphosphates - chemistry | Diphosphonates - chemistry | Hydrophobic and Hydrophilic Interactions | Saccharomyces cerevisiae - enzymology | Isoenzymes - antagonists & inhibitors | Usage | Research | X-ray spectroscopy | Plant cell walls | Guanosine triphosphatase | Biochemistry | Inhibitor drugs | Drug therapy | Index Medicus | Biological Sciences | undecaprenyl diphosphate synthase | x-ray structure | geranylgeranyl diphosphate synthase | cell wall
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 12/2011, Volume 20, Issue 24, pp. 4851 - 4864
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2012, Volume 167, Issue 7, pp. 1506 - 1519
Journal Article