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JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 12, pp. 1502 - 1503
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 5, pp. 601 - 601
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2010, Volume 55, Issue 23, pp. 2556 - 2566
Objectives The aim of this study was to develop a practical risk score to predict the risk and implications of major bleeding in acute coronary syndromes... 
Cardiovascular | Internal Medicine | mortality | bleeding | myocardial infarction | risk score | STRATEGY ACUITY TRIAL | ISCHEMIC EVENTS | ELUTING STENT | CARDIAC & CARDIOVASCULAR SYSTEMS | ACUTE CATHETERIZATION | GLOBAL REGISTRY | RANDOMIZED-TRIAL | GLYCOPROTEIN IIB/IIIA INHIBITORS | ACUTE MYOCARDIAL-INFARCTION | UNSTABLE ANGINA | CLINICAL-OUTCOMES | Multivariate Analysis | Predictive Value of Tests | Confidence Intervals | Platelet Glycoprotein GPIIb-IIIa Complex - adverse effects | Humans | Middle Aged | Acute Coronary Syndrome - mortality | Hemorrhage - mortality | Heparin - therapeutic use | Male | Heparin - adverse effects | Cause of Death | Hospital Mortality - trends | Fibrinolytic Agents - adverse effects | Fibrinolytic Agents - therapeutic use | Aged, 80 and over | Electrocardiography | Female | Platelet Aggregation Inhibitors - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Severity of Illness Index | Coronary Artery Bypass - methods | Risk Assessment | Angioplasty, Balloon, Coronary - methods | Kaplan-Meier Estimate | Proportional Hazards Models | Probability | Treatment Outcome | Acute Coronary Syndrome - drug therapy | Coronary Angiography | Acute Coronary Syndrome - diagnosis | Survival Analysis | Platelet Glycoprotein GPIIb-IIIa Complex - therapeutic use | Acute Coronary Syndrome - therapy | Aged | Hemorrhage - chemically induced | Transluminal angioplasty | Sects | Medical research | Coronary artery bypass | Cardiac patients | Mortality | Medicine, Experimental | Health aspects | Coronary heart disease | Risk factors | Medical colleges | Blood transfusions | Heart attacks | Medical imaging | Blood products | Data bases | Confidence intervals | Biomarkers | Intubation | Acute coronary syndromes | Age | Logistics
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 69, Issue 3, pp. 345 - 357
Abstract Propensity scores (PS) are an increasingly popular method to adjust for confounding in observational studies. Propensity score methods have... 
Cardiovascular | Internal Medicine | comparison of methods | observational studies | regression | bias | Heart failure | Medical colleges | Comparative analysis | Mortality | Methods
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 69, Issue 20, pp. 2576 - 2577
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2014, Volume 64, Issue 15, pp. 1615 - 1628
Abstract This paper describes some important controversies regarding the current state of clinical trials research in cardiology. Topics covered include the... 
Cardiovascular | Internal Medicine | clinical trial | placebo effect | research design | statistical analysis | random allocation | public health | reporting
Journal Article
American Heart Journal, ISSN 0002-8703, 2011, Volume 162, Issue 5, pp. 900 - 906
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2015, Volume 66, Issue 23, pp. 2648 - 2662
Abstract This paper tackles several statistical controversies that are commonly faced when reporting a major clinical trial. Topics covered include:... 
Cardiovascular | Internal Medicine | intention-to-treat analysis | logistic models | risk assessment | randomized controlled trials as topic | proportional hazards models | statistics | Clinical trials | Confidence intervals | Hypotheses | Heart attacks | Statistical analysis | Funding | Statistical methods | Acute coronary syndromes
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2015, Volume 66, Issue 22, pp. 2536 - 2549
Abstract This paper is a practical guide to the essentials of statistical analysis and reporting of randomized clinical trials (RCTs). It is the first in a... 
Cardiovascular | Internal Medicine | clinical trials | interpretation | publication | statistics | Clinical trials | Statistics | Heart failure | Heart attacks | Statistical analysis | Mortality | Hospitalization | Family medical history | Estimates | Patients | Clinical outcomes | Confidence intervals | Diabetes | Acute coronary syndromes | Chronic illnesses
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 68, Issue 24, pp. 2608 - 2618
Journal Article
Journal Article
American Heart Journal, ISSN 0002-8703, 2015, Volume 171, Issue 1, pp. 40 - 47
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2015, Volume 66, Issue 25, pp. 2886 - 2898
Abstract As a sequel to last week’s paper on the fundamentals of clinical trial design, this paper tackles related controversial issues: noninferiority trials,... 
Cardiovascular | Internal Medicine | strategy trials | Data Monitoring Committees | statistical stopping guidelines | noninferiority trials | factorial designs | adaptive designs | randomized controlled trials as topic | Clinical trials | Studies | Hypertension | Design | Confidence intervals | Aspirin | Heart attacks | Ischemia | Acute coronary syndromes | Patients
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2015, Volume 66, Issue 24, pp. 2757 - 2766
Abstract This paper provides practical guidance on the fundamentals of design for major randomized controlled trials. Topics covered include the choice of... 
Cardiovascular | Internal Medicine | avoidance of bias | selection of patients | study design | treatments and endpoints | sample size | randomized controlled trial | Clinical trials | Heart failure | Heart attacks | Mortality | Stratigraphy | Diabetes | Cardiology | Acute coronary syndromes | Patients | Drug dosages | Methods
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2008, Volume 51, Issue 20, pp. 1992 - 1992
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2015, Volume 66, Issue 11, pp. 1273 - 1285
Abstract Little is known about the benefits and risks of the long-term use of cardiovascular drugs. Evidence from randomized clinical trials (RCTs) rarely goes... 
Cardiovascular | Internal Medicine | long-term treatment | cardiovascular medications | randomized clinical trials | deprescribing | elderly | polypharmacy | Enzymes | Aspirin | Usage | Cardiac patients | Angiotensin | Drug therapy | Heart attack | Statins | Cardiovascular disease | Heart attacks | Cardiology | Cholesterol
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2016, Volume 118, Issue 11, pp. 1661 - 1668
Women are frequently reported to have increased morbidity after presentation with acute coronary syndromes and myocardial infarction; however, whether a... 
Cardiovascular | BIVALIRUDIN | MORTALITY | REVASCULARIZATION | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOPLASTY | RISK | SEX-DIFFERENCES | POSTMENOPAUSAL WOMEN | ELEVATION MYOCARDIAL-INFARCTION | PLATELET REACTIVITY | INSIGHTS | United States - epidemiology | Antineoplastic Agents, Phytogenic | Paclitaxel - pharmacology | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Heparin - administration & dosage | Male | Thromboembolism - epidemiology | ST Elevation Myocardial Infarction - diagnosis | Incidence | Hospital Mortality - trends | Thromboembolism - prevention & control | Time Factors | Platelet Aggregation Inhibitors - administration & dosage | Ticlopidine - administration & dosage | Female | Intraoperative Complications - epidemiology | Drug-Eluting Stents | Survival Rate - trends | Risk Assessment | Risk Factors | Europe - epidemiology | Thromboembolism - etiology | Ticlopidine - analogs & derivatives | Coronary Angiography | ST Elevation Myocardial Infarction - mortality | ST Elevation Myocardial Infarction - surgery | Sex Factors | Sex Distribution | Aged | Percutaneous Coronary Intervention - adverse effects | New South Wales - epidemiology | Transluminal angioplasty | Medical colleges | Coronary heart disease | Analysis | Hypertension | Women | Heart attacks | Medical imaging | Heart surgery | Laboratories | Aneurysms | Gender differences | Thrombosis | Blood clots | Variables | Coronary vessels | Intubation | Diabetes | Acute coronary syndromes | Stents | Veins & arteries
Journal Article