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by Nalls, Michael A and Plagnol, Vincent and Hernandez, Dena G and Sharma, Manu and Sheerin, Una-Marie and Saad, Mohamad and Simon-Sanchez, Javier and Schulte, Claudia and Lesage, Suzanne and Sveinbjornsdottir, Sigurlaug and Arepalli, Sampath and Barker, Roger and Ben-Shlomo, Yoav and Berendse, Henk W and Berg, Daniela and Bhatia, Kailash and de Bie, Rob M. A and Biffi, Alessano and Bloem, Bas and Bochdanovits, Zoltan and Bonin, Michael and Bras, Jose M and Brockmann, Kathrin and Brooks, Janet and Burn, David J and Charlesworth, Gavin and Chen, Honglei and Chinnery, Patrick F and Chong, Sean and Clarke, Carl E and Cookson, Mark R and Cooper, J. Mark and Corvol, Jean Christophe and Counsell, Carl and Damier, Philippe and Dartigues, Jean-Francois and Deloukas, Panos and Deuschl, Guenther and Dexter, David T and van Dijk, Karin D and Dillman, Allissa and Durif, Frank and Duerr, Alexana and Edkins, Sarah and Evans, Jonathan R and Foltynie, Thomas and Gao, Jianjun and Gardner, Michelle and Gibbs, J. Raphael and Goate, Alison and Gray, Emma and Guerreiro, Rita and Gustafsson, Omar and Harris, Clare and van Hilten, Jacobus J and Hofman, Albert and Hollenbeck, Albert and Holton, Janice and Hu, Michele and Huang, Xuemei and Huber, Heiko and Hudson, Gavin and Hunt, Sarah E and Huttenlocher, Johanna and Illig, Thomas and Jonsson, Palmi V and Lambert, Jean-Charles and Langford, Cordelia and Lees, Anew and Lichtner, Peter and Limousin, Patricia and Lopez, Grisel and Lorenz, Delia and McNeill, Alisdair and Moorby, Catriona and Moore, Matthew and Morris, Huw R and Morrison, Karen E and Mudanohwo, Ese and O'Sullivan, Sean S and Pearson, Justin and Perlmutter, Joel S and Petursson, Hjoervar and Pollak, Pierre and Post, Bart and Potter, Simon and Ravina, Bernard and Revesz, Tamas and Riess, Olaf and Rivadeneira, Fernando and Rizzu, Patrizia and Ryten, Mina and Sawcer, Stephen and Schapira, Anthony and Scheffer, Hans and Shaw, Karen and Shoulson, Ira and Siansky, Ellen and Smith, Colin and Spencer, Chris C. A and ... and Wellcome Trust Case-Control Consor and Int Parkinson Dis Genomics Consort and International Parkinson Disease Genomics Consortium
Lancet, The, ISSN 0140-6736, 2011, Volume 377, Issue 9766, pp. 641 - 649
Journal Article
by Nalls, Mike A and Pankratz, Nathan and Lill, Christina M and Do, Chuong B and Hernandez, Dena G and Saad, Mohamad and DeStefano, Anita L and Kara, Eleanna and Bras, Jose and Sharma, Manu and Schulte, Claudia and Keller, Margaux F and Arepalli, Sampath and Letson, Christopher and Edsall, Connor and Stefansson, Hreinn and Liu, Xinmin and Pliner, Hannah and Lee, Joseph H and Cheng, Rong and Ikram, M. Arfan and Ioannidis, John P. A and Hadjigeorgiou, Georgios M and Bis, Joshua C and Martinez, Maria and Perlmutter, Joel S and Goate, Alison and Marder, Karen and Fiske, Brian and Sutherland, Margaret and Xiromerisiou, Georgia and Myers, Richard H and Clark, Lorraine N and Stefansson, Kari and Hardy, John A and Heutink, Peter and Chen, Honglei and Wood, Nicholas W and Houlden, Henry and Payami, Haydeh and Brice, Alexis and Scott, William K and Gasser, Thomas and Bertram, Lars and Eriksson, Nicholas and Foroud, Tatiana and Singleton, Anew B and Plagnol, Vincent and Sheerin, Una-Marie and Simón-Sánchez, Javier and Lesage, Suzanne and Sveinbjörnsdóttir, Sigurlaug and Barker, Roger and Ben-Shlomo, Yoav and Berendse, Henk W and Berg, Daniela and Bhatia, Kailash and de Bie, Rob M. A and Biffi, Alessano and Bloem, Bas and Bochdanovits, Zoltan and Bonin, Michael and Bras, Jose M and Brockmann, Kathrin and Brooks, Janet and Burn, David J and Charlesworth, Gavin and Chinnery, Patrick F and Chong, Sean and Clarke, Carl E and Cookson, Mark R and Cooper, J. Mark and Corvol, Jean Christophe and Counsell, Carl and Damier, Philippe and Dartigues, Jean-François and Deloukas, Panos and Deuschl, Günther and Dexter, David T and van Dijk, Karin D and Dillman, Allissa and Durif, Frank and Dürr, Alexana and Edkins, Sarah and Evans, Jonathan R and Foltynie, Thomas and Dong, Jing and Gardner, Michelle and Gibbs, J. Raphael and Gray, Emma and Guerreiro, Rita and Harris, Clare and van Hilten, Jacobus J and Hofman, Albert and Hollenbeck, Albert and Holton, Janice and Hu, Michele and Huang, Xuemei and Wurster, Isabel and Mätzler, Walter and ... and GenePD and IPDG and Ashkenazi Jewish Dataset Investiga and 23AndMe and NABEC and HIHG and Greek Parkinson's Dis Consortium and GParkinson's Study Grp PSG Parkins and NGRC and Alzheimer Genetic Analysis Gr and CHARGE and UKBEC and Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI) and Hussman Institute of Human Genomics (HIHG) and 23andMe and Greek Parkinson's Disease Consortium and International Parkinson's Disease Genomics Consortium (IPDGC) and Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE) and United Kingdom Brain Expression Consortium (UKBEC) and NeuroGenetics Research Consortium (NGRC) and Ashkenazi Jewish Dataset Investigator and North American Brain Expression Consortium (NABEC) and Alzheimer Genetic Analysis Group and The Ashkenazi Jewish Dataset Investigator
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 9, pp. 989 - +
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2014, Volume 111, Issue 7, pp. 2626 - 2631
Mutations in leucine-rich repeat kinase 2 (LRRK2) cause inherited Parkinson disease (PD), and common variants around LRRK2 are a risk factor for sporadic PD.... 
Proteins | Neurites | Transfection | Neurons | Medical genetics | Parkinson disease | Disease risk | Genetic loci | Gene expression regulation | Genetic mutation | GAK | Trans-Golgi | BAG5 | Autophagy | RECRUITMENT | autophagy | PROTEIN | VARIANTS | LRRK2 | MULTIDISCIPLINARY SCIENCES | SEQUENCE | trans-Golgi | CLATHRIN | Cell Fractionation | Immunoprecipitation | Humans | Genetic Loci - genetics | Multiprotein Complexes - genetics | DNA Primers - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Brain - metabolism | Multiprotein Complexes - metabolism | Mass Spectrometry | HEK293 Cells | Plasmids - genetics | Golgi Apparatus - ultrastructure | Protein-Serine-Threonine Kinases - metabolism | rab GTP-Binding Proteins - metabolism | Genetic Predisposition to Disease - genetics | Protein-Serine-Threonine Kinases - genetics | Blotting, Western | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Microscopy, Confocal | Protein Interaction Mapping - methods | Analysis of Variance | Transport Vesicles - metabolism | Parkinson Disease - enzymology | Adaptor Proteins, Signal Transducing - metabolism | Genome-Wide Association Study - methods | Genetic aspects | Parkinson's disease | Leucine | Gene mutations | Health aspects | Phosphotransferases | Mutation | Kinases | Genes | Parkinsons disease | Index Medicus | Biological Sciences
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2015, Volume 372, Issue 25, pp. 2387 - 2397
In this trial, patients with an acute coronary syndrome within the previous 10 days were randomly assigned to simvastatin plus either ezetimibe or placebo. At... 
CHOLESTEROL ABSORPTION | CARDIAC OUTCOMES | MEDICINE, GENERAL & INTERNAL | MYOCARDIAL-INFARCTION | EFFICACY | CARDIOVASCULAR OUTCOMES | CLINICAL-TRIALS | SIMVASTATIN | PRIMARY PREVENTION | IMPROVE-IT | ATORVASTATIN | Simvastatin - therapeutic use | Double-Blind Method | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Azetidines - adverse effects | Ezetimibe | Kaplan-Meier Estimate | Male | Anticholesteremic Agents - adverse effects | Acute Coronary Syndrome - drug therapy | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Azetidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Triglycerides - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Cholesterol, LDL - blood | Female | Aged | Drug Therapy, Combination | Usage | Simvastatin | Analysis | Practice guidelines (Medicine) | Dosage and administration | Drug therapy, Combination | Acute coronary syndrome | Drug therapy | Myocardial infarction | Cerebral infarction | Lipoproteins (low density) | Stroke | Liver | Angina | Cholesterol | Intestine | Gallbladder | Acute coronary syndromes | Cardiovascular diseases | Statins | Pharmaceuticals | Cancer | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology | Cardiology and cardiovascular system
Journal Article