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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2014, Volume 111, Issue 7, pp. 2626 - 2631
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 2192 - 2192
Metformin is a drug commonly prescribed to treat patients with type 2 diabetes. Here we show that long-term treatment with metformin (0.1% w/w in diet)... 
COMPLEX I | HEPATIC GLUCONEOGENESIS | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | RESPIRATION | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | AMPK | DIETARY RESTRICTION | ANTIDIABETIC DRUG METFORMIN | CANCER | Index Medicus
Journal Article
by Lesage, Suzanne and Drouet, Valérie and Majounie, Elisa and Deramecourt, Vincent and Jacoupy, Maxime and Nicolas, Aude and Cormier-Dequaire, Florence and Hassoun, Sidi Mohamed and Pujol, Claire and Ciura, Sorana and Erpapazoglou, Zoi and Usenko, Tatiana and Maurage, Claude-Alain and Sahbatou, Mourad and Liebau, Stefan and Ding, Jinhui and Bilgic, Basar and Emre, Murat and Erginel-Unaltuna, Nihan and Guven, Gamze and Tison, François and Tranchant, Christine and Vidailhet, Marie and Corvol, Jean Christophe and Corvol, Jean-Christophe and Krack, Paul and Leutenegger, Anne-Louise and Nalls, Michael A and Hernandez, Dena G and Heutink, Peter and Gibbs, J. Raphael and Hardy, John and Wood, Nicholas W and Gasser, Thomas and Durr, Alexandra and Deleuze, Jean-François and Tazir, Meriem and Destée, Alain and Lohmann, Ebba and Kabashi, Edor and Singleton, Andrew B and Singleton, Andrew and Corti, Olga and Brice, Alexis and Agid, Yves and Anheim, Mathieu and Bonnet, Anne-Marie and Borg, Michel and Broussolle, Emmanuel and Damier, Philippe and Dürr, Alexandra and Durif, Frank and Durif, Franck and Klebe, Stephan and Martinez, María and Martinez, Maria and Pollak, Pierre and Rascol, Olivier and Vérin, Marc and Viallet, François and Arepalli, Sampath and Barker, Roger A and Ben-Shlomo, Yoav and Berg, Daniela and Bettella, Francesco and Bhatia, Kailash and de Bie, Rob M.A and Biffi, Alessandro and Bloem, Bastiaan R and Bochdanovits, Zoltan and Bonin, Michael and Bras, Jose M and Brockmann, Kathrin and Brooks, Janet and Burn, David J and Charlesworth, Gavin and Chen, Honglei and Chinnery, Patrick F and Chong, Sean and Clarke, Carl E and Cookson, Mark R and Counsell, Carl and Dartigues, Jean-François and Deloukas, Panos and Deuschl, Günther and Dexter, David T and van Dijk, Karin D and Dillman, Allissa and Dong, Jing and Edkins, Sarah and Escott-Price, Valentina and Evans, Jonathan R and Foltynie, Thomas and Gao, Jianjun and Gardner, Michelle and Goate, Alison and Gray, Emma and Guerreiro, Rita and Harris, Clare and van Hilten, Jacobus J and ... and French Parkinson's Disease Genetics Study (PDG) and International Parkinson's Disease Genomics Consortium (IPDGC)
The American Journal of Human Genetics, ISSN 0002-9297, 03/2016, Volume 98, Issue 3, pp. 500 - 513
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 11/2011, Volume 208, Issue 12, pp. 2357 - 2366
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 01/2017, Volume 13, Issue 1, p. e1005337
Journal Article
PLoS computational biology, 01/2017, Volume 13, Issue 1, p. e1005337
We model the regulatory role of proteins bound to looped DNA using a simulation in which dsDNA is represented as a self-avoiding chain, and proteins as... 
DNA - chemistry | Animals | Computational Biology | Enhancer Elements, Genetic - genetics | Models, Genetic | DNA - metabolism | Transcription Factors - genetics | Drosophila melanogaster - genetics | Monte Carlo Method
Journal Article
by Nalls, Mike A and Pankratz, Nathan and Lill, Christina M and Do, Chuong B and Hernandez, Dena G and Saad, Mohamad and DeStefano, Anita L and Kara, Eleanna and Bras, Jose and Sharma, Manu and Schulte, Claudia and Keller, Margaux F and Arepalli, Sampath and Letson, Christopher and Edsall, Connor and Stefansson, Hreinn and Liu, Xinmin and Pliner, Hannah and Lee, Joseph H and Cheng, Rong and Ikram, M. Arfan and Ioannidis, John P. A and Hadjigeorgiou, Georgios M and Bis, Joshua C and Martinez, Maria and Perlmutter, Joel S and Goate, Alison and Marder, Karen and Fiske, Brian and Sutherland, Margaret and Xiromerisiou, Georgia and Myers, Richard H and Clark, Lorraine N and Stefansson, Kari and Hardy, John A and Heutink, Peter and Chen, Honglei and Wood, Nicholas W and Houlden, Henry and Payami, Haydeh and Brice, Alexis and Scott, William K and Gasser, Thomas and Bertram, Lars and Eriksson, Nicholas and Foroud, Tatiana and Singleton, Anew B and Plagnol, Vincent and Sheerin, Una-Marie and Simón-Sánchez, Javier and Lesage, Suzanne and Sveinbjörnsdóttir, Sigurlaug and Barker, Roger and Ben-Shlomo, Yoav and Berendse, Henk W and Berg, Daniela and Bhatia, Kailash and de Bie, Rob M. A and Biffi, Alessano and Bloem, Bas and Bochdanovits, Zoltan and Bonin, Michael and Bras, Jose M and Brockmann, Kathrin and Brooks, Janet and Burn, David J and Charlesworth, Gavin and Chinnery, Patrick F and Chong, Sean and Clarke, Carl E and Cookson, Mark R and Cooper, J. Mark and Corvol, Jean Christophe and Counsell, Carl and Damier, Philippe and Dartigues, Jean-François and Deloukas, Panos and Deuschl, Günther and Dexter, David T and van Dijk, Karin D and Dillman, Allissa and Durif, Frank and Dürr, Alexana and Edkins, Sarah and Evans, Jonathan R and Foltynie, Thomas and Dong, Jing and Gardner, Michelle and Gibbs, J. Raphael and Gray, Emma and Guerreiro, Rita and Harris, Clare and van Hilten, Jacobus J and Hofman, Albert and Hollenbeck, Albert and Holton, Janice and Hu, Michele and Huang, Xuemei and Wurster, Isabel and Mätzler, Walter and ... and GenePD and IPDG and Ashkenazi Jewish Dataset Investiga and 23AndMe and NABEC and HIHG and Greek Parkinson's Dis Consortium and GParkinson's Study Grp PSG Parkins and NGRC and Alzheimer Genetic Analysis Gr and CHARGE and UKBEC and Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI) and Hussman Institute of Human Genomics (HIHG) and 23andMe and Greek Parkinson's Disease Consortium and International Parkinson's Disease Genomics Consortium (IPDGC) and Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE) and United Kingdom Brain Expression Consortium (UKBEC) and NeuroGenetics Research Consortium (NGRC) and Ashkenazi Jewish Dataset Investigator and North American Brain Expression Consortium (NABEC) and Alzheimer Genetic Analysis Group and The Ashkenazi Jewish Dataset Investigator
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 9, pp. 989 - +
Journal Article