X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (67) 67
male (59) 59
animals (45) 45
humans (39) 39
article (33) 33
rats (29) 29
female (27) 27
rats, sprague-dawley (25) 25
neurosciences (21) 21
brain (20) 20
pharmacology & pharmacy (20) 20
critical care medicine (19) 19
subarachnoid hemorrhage (19) 19
middle aged (18) 18
adult (17) 17
traumatic brain injury (17) 17
arachidonic-acid (16) 16
mice (16) 16
arachidonic acid (14) 14
cytochrome p-450 enzyme system - metabolism (14) 14
pharmacokinetics (14) 14
research (14) 14
aged (13) 13
clinical neurology (12) 12
neuroprotection (11) 11
pharmacy (11) 11
20-hydroxyeicosatetraenoic acid (10) 10
adolescent (10) 10
injuries (10) 10
lipids (10) 10
metabolism (10) 10
analysis (9) 9
controlled cortical impact (9) 9
disease models, animal (9) 9
drug metabolism (9) 9
endocrinology & metabolism (9) 9
enzymes (9) 9
expression (9) 9
hydroxyeicosatetraenoic acids - metabolism (9) 9
nursing (9) 9
rodents (9) 9
cardiovascular system (8) 8
cerebral-blood-flow (8) 8
hypothermia (8) 8
hypothermia, induced (8) 8
ischemia (8) 8
liver - enzymology (8) 8
mass spectrometry (8) 8
original (8) 8
pharmaceutical sciences (8) 8
stroke (8) 8
young adult (8) 8
20-hete (7) 7
abridged index medicus (7) 7
biomarker (7) 7
cells, cultured (7) 7
drug therapy (7) 7
metabolites (7) 7
neurology (7) 7
original article (7) 7
pediatrics (7) 7
prospective studies (7) 7
rat (7) 7
risk factors (7) 7
therapeutic hypothermia (7) 7
time factors (7) 7
treatment outcome (7) 7
vasospasm (7) 7
arachidonic acid - metabolism (6) 6
biochemistry & molecular biology (6) 6
biomarkers - blood (6) 6
brain - metabolism (6) 6
brain damage (6) 6
cardiac arrest (6) 6
care and treatment (6) 6
cerebrospinal fluid (6) 6
children (6) 6
critical care (6) 6
cytochrome p-450 cyp2e1 - metabolism (6) 6
delayed cerebral ischemia (6) 6
education, scientific disciplines (6) 6
graduate education (6) 6
hematology (6) 6
kidney - metabolism (6) 6
liver - metabolism (6) 6
medicine (6) 6
mice, inbred c57bl (6) 6
microsomes, liver - enzymology (6) 6
model (6) 6
moderate hypothermia (6) 6
original articles (6) 6
soluble epoxide hydrolase (6) 6
subarachnoid hemorrhage - cerebrospinal fluid (6) 6
subarachnoid hemorrhage - genetics (6) 6
therapy (6) 6
traumatic brain-injury (6) 6
articles (5) 5
biochemical research methods (5) 5
biomarkers (5) 5
blood-flow (5) 5
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of neurotrauma, ISSN 0897-7151, 02/2019
The purpose of this review is to highlight the pharmacologic barrier to drug development for traumatic brain injury (TBI) and to discuss best practice... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2017, Volume 114, Issue 38, pp. E7997 - E8006
Journal Article
Nature Chemistry, ISSN 1755-4330, 2014, Volume 6, Issue 6, pp. 542 - 552
Journal Article
Experimental Neurology, ISSN 0014-4886, 07/2019, Volume 317, pp. 10 - 21
Membrane transporters regulate the trafficking of endogenous and exogenous molecules across biological barriers and within the neurovascular unit. In traumatic... 
ATP-binding cassette transporters | Traumatic brain injury | Neurovascular unit | Solute carriers | Blood-brain barrier | Multidrug resistance | Brain | Medical research | Drug resistance in microorganisms | Neurons | Medicine, Experimental | Amino acids | Single nucleotide polymorphisms | Glutamate | Injuries | Blood proteins
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, p. e110162
Fatty liver disease is an emerging public health problem without effective therapies, and chronic hepatic inflammation is a key pathologic mediator in its... 
SOLUBLE EPOXIDE HYDROLASE | HYDRODYNAMICS-BASED TRANSFECTION | MULTIDISCIPLINARY SCIENCES | MOUSE | ATHEROGENIC DIET | NONALCOHOLIC STEATOHEPATITIS | EICOSANOID METABOLISM | MICE | ARACHIDONIC-ACID | LARGE GENE LISTS | ENDOTHELIAL EXPRESSION | Biomarkers - metabolism | Fatty Liver - genetics | Epoxide Hydrolases - deficiency | Inflammation - pathology | Arachidonic Acid - metabolism | Liver - pathology | Liver - enzymology | Fatty Liver - blood | Fatty Liver - pathology | Mice, Inbred C57BL | Gene Expression Regulation | Cytochrome P-450 Enzyme System - metabolism | Hydrodynamics | Male | Inflammation - blood | Metabolic Networks and Pathways - genetics | Animals | Diet | Eicosanoids - metabolism | Lipids - blood | Atherosclerosis | Fatty Liver - enzymology | Inflammation - genetics | Epoxide Hydrolases - metabolism | Unsaturated fatty acids | Inflammation | Fatty liver | Analysis | Cytochrome P-450 | Cytochrome | Health sciences | Liver | Inflammatory response | Cardiovascular disease | Biosynthesis | Arachidonic acid | Phosphatase | Epoxide hydrolase | Biological effects | Atherogenic diet | Rodents | Hepatology | Drug therapy | Pharmaceutical sciences | Public health | Cardiovascular system | Enzymes | Liver diseases | Cytochrome P450 | Environmental health | Metabolism | Gene expression | Cholesterol | Biological activity | Nutrition research | Acids | Pharmacy | Mice | Laboratory animals | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0180280
There are no therapies shown to improve outcome after severe traumatic brain injury (TBI) in humans, a leading cause of morbidity and mortality. We sought to... 
Intracranial Pressure - drug effects | Adjuvants, Pharmaceutic - pharmacology | Humans | Probenecid - blood | Child, Preschool | Acetylcysteine - cerebrospinal fluid | Male | Brain Injuries, Traumatic - cerebrospinal fluid | Glasgow Coma Scale | Intubation, Gastrointestinal | Female | Brain Injuries, Traumatic - blood | Probenecid - pharmacokinetics | Child | Brain Injuries, Traumatic - drug therapy | Double-Blind Method | Drug Administration Schedule | Probenecid - pharmacology | Glasgow Outcome Scale | Antioxidants - pharmacology | Biomarkers - blood | Body Temperature | Acetylcysteine - blood | Acetylcysteine - pharmacokinetics | Acetylcysteine - pharmacology | Adolescent | Survival Analysis | Adjuvants, Pharmaceutic - pharmacokinetics | Antioxidants - pharmacokinetics | Brain Injuries, Traumatic - mortality | Probenecid - cerebrospinal fluid | Brain | Usage | Clinical trials | Acetylcysteine | Children | Research | Health aspects | Injuries | Probenecid | Testing | Coma | Pediatrics | Drug delivery systems | Traumatic brain injury | Physicians | Critical care | Intracranial pressure | Cerebrospinal fluid | Epidemiology | Antioxidants | Randomization | Head injuries | Temperature effects | Rodents | Blood pressure | Pharmaceutical sciences | Antimicrobial agents | Patients | Morbidity | Medicine | Side effects | Brain research | Hospitals | Pharmacy | Biomarkers | Informed consent | Ventricle
Journal Article
Pediatric Research, ISSN 0031-3998, 07/2017, Volume 82, Issue 1, pp. 29 - 35
BACKGROUND: The gene ABCB1 encodes p-glycoprotein, a xenobiotic efflux pump capable of transporting certain opioids, including fentanyl. ABCB1 genotype has... 
PEDIATRIC INTENSIVE-CARE | PAIN | MANAGEMENT | TRAUMATIC BRAIN-INJURY | SEDATION | PEDIATRICS | P-GLYCOPROTEIN EXPRESSION | GENE POLYMORPHISMS | WITHDRAWAL | DEPENDENCE | ANALGESIA | Genotype & phenotype | Pediatrics | Drug delivery systems | Glycoproteins
Journal Article
Expert Opinion on Drug Metabolism & Toxicology, ISSN 1742-5255, 07/2011, Volume 7, Issue 7, pp. 803 - 816
Journal Article
Journal Article
Journal of Neurotrauma, ISSN 0897-7151, 03/2016, Volume 33, Issue 6, pp. 66 - 614
Journal Article