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Nature Cell Biology, ISSN 1465-7392, 2015, Volume 17, Issue 8, pp. 1074 - 1087
Defects in primary cilium biogenesis underlie the ciliopathies, a growing group of genetic disorders. We describe a whole-genome siRNA-based reverse genetics... 
JOUBERT-SYNDROME | RPGRIP1 | TRANSPORT | CENTRIOLE BIOGENESIS | PROTEIN | C-ELEGANS | MUTATIONS | PHOTORECEPTOR CELLS | MASTER REGULATOR | PRIMARY CILIA | CELL BIOLOGY | Humans | Pregnancy Proteins - genetics | Databases, Genetic | Suppressor Factors, Immunologic - genetics | Photoreceptor Cells - ultrastructure | Pregnancy Proteins - metabolism | Ellis-Van Creveld Syndrome - genetics | Cerebellum - abnormalities | Genetic Testing - methods | Suppressor Factors, Immunologic - metabolism | Membrane Proteins - deficiency | Transfection | RNA Interference | HEK293 Cells | Kidney Diseases, Cystic - genetics | Genomics - methods | Genetic Predisposition to Disease | Genome-Wide Association Study | Reproducibility of Results | Caenorhabditis elegans - metabolism | Cilia - pathology | Caenorhabditis elegans - genetics | Membrane Proteins - genetics | Mice, Inbred C57BL | Abnormalities, Multiple | Genetic Markers | Eye Abnormalities - genetics | Cilia - metabolism | Zebrafish - genetics | Cilia - genetics | Mice, Knockout | Proteins - genetics | Caenorhabditis elegans - ultrastructure | Phenotype | Animals | Cerebellar Diseases - genetics | Ciliary Motility Disorders - pathology | Proteins - metabolism | Photoreceptor Cells - metabolism | Zebrafish - metabolism | Retina - abnormalities | High-Throughput Nucleotide Sequencing | Ciliary Motility Disorders - metabolism | Mutation | Ciliary Motility Disorders - genetics | RNA | Cilia and ciliary motion | Genetic research | Biosynthesis | Genetic aspects | Research | Gene expression | Properties | reverse genetics | cilia | ciliopathies | Joubert syndrome | whole-genome siRNA screen | Jeune syndrome
Journal Article
Journal of Heart and Lung Transplantation, ISSN 1053-2498, 2015, Volume 34, Issue 4, pp. S329 - S330
Journal Article
Boreas, ISSN 0300-9483, 01/2014, Volume 43, Issue 1, pp. 175 - 192
Hafnium (Hf) and zirconium (Zr) concentrations measured in over 4100 agricultural soil samples from Europe were assessed with the focus on their relationship... 
LOESS | SAND | GEOGRAPHY, PHYSICAL | GEOSCIENCES, MULTIDISCIPLINARY | EASTERN | SOUTHERN ENGLAND | ACCUMULATION | COVERSAND | STRATIGRAPHY | FRANCE | THERMOLUMINESCENCE | PALEOSOLS | Loess | Soils | Zirconium | Analysis
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 2001, Volume 123, Issue 21, pp. 4896 - 4903
Journal Article
Canadian Society of Forensic Science Journal, ISSN 0008-5030, 01/2009, Volume 42, Issue 1, pp. 1 - 29
The standards and procedures presented are intended as recommendations that encourage the development of a quality system or best practices within a breath... 
Journal Article
Canadian Society of Forensic Science Journal, ISSN 0008-5030, 01/2009, Volume 42, Issue 1, pp. 31 - 61
Journal Article
Canadian Society of Forensic Science Journal, ISSN 0008-5030, 01/2009, Volume 42, Issue 1, pp. 31 - 61
Journal Article
Science, ISSN 0036-8075, 7/1988, Volume 241, Issue 4865, pp. 551 - 557
A series of four hairpin deoxyoligonucleotides was synthesized with a four-nucleotide central loop (either C or G) flanked by the complementary sequences... 
Oligomers | Molecules | Gels | DNA | Oligonucleotides | Ultraviolet spectrum | Chemical bases | Fluorescence | Spectral index | Absorption spectra | Thermodynamics | Hydrogen Bonding | Electrophoresis, Polyacrylamide Gel | Models, Molecular | Nucleic Acid Conformation | Spectrum Analysis | Synthesis | Research | Molecular structure | Organic compounds | Genetics
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 1987, Volume 28, Issue 32, pp. 3643 - 3646
5-(p-nitrophenyl) tetrazole/DMAP mixtures are more effective phosphoramidite activators than either tetrazole, 5-(o-nitrophenyl) tetrazole or 5-(p-nitrophenyl)... 
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 1989, Volume 17, Issue 9, pp. 3501 - 3517
Strong aqueous ammonium hydroxide used to remove N-acyl protecting groups from synthetic oligoribonucleotides causes removal of some alkylsilyl protecting... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | Hydrolysis | Oligoribonucleotides - chemical synthesis | Drug Stability | Oligoribonucleotides - isolation & purification | Indicators and Reagents | Silicon | Structure-Activity Relationship | Chromatography, High Pressure Liquid
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 1991, Volume 32, Issue 14, pp. 1715 - 1718
An N-dimethoxytritylated biotin group coupled to a 6-aminohexanol linker was converted into a phosphoramidite to yield a biotinylating reagent which can be... 
CHEMISTRY, ORGANIC | OLIGODEOXYRIBONUCLEOTIDES | HYBRIDIZATION PROBES
Journal Article
Nucleosides, Nucleotides and Nucleic Acids, ISSN 1525-7770, 03/2001, Volume 20, Issue 4-7, pp. 985 - 989
Multiple oligonucleotides linked end-to-end in tandem can be synthesized by adding a nucleoside to the 5′-OH end of a prior sequence. Nucleosides with... 
REAGENTS | ACID Q-LINKER | NUCLEOSIDES | BIOCHEMISTRY & MOLECULAR BIOLOGY | Organophosphorus Compounds - chemistry | Nucleosides - chemistry | Tandem Repeat Sequences | Pyridines - chemistry | Cross-Linking Reagents - chemical synthesis | Oligonucleotides - chemical synthesis
Journal Article
BioTechniques, ISSN 0736-6205, 09/1999, Volume 27, Issue 3, pp. 528 - 536
This study surveyed strategies of sequencing primer selection and evaluated primer performance in automated DNA sequencing. We asked participants to relate... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | HYBRIDIZATION | BIOCHEMICAL RESEARCH METHODS | Rhodamines | Chemical Phenomena | Drug Design | Indicators and Reagents | Software | DNA Primers - chemistry | Chemistry, Physical | Dimerization | Sequence Analysis, DNA | DNA Primers - chemical synthesis | Fluorescent Dyes | Autoanalysis
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 07/1995, Volume 212, Issue 3, p. 995
Journal Article
BioTechniques, ISSN 0736-6205, 1988, Volume 6, Issue 8, pp. 768 - 775
An improved and simplified procedure for the attachment of nucleosides onto long chain alkylamine controlled pore glass beads (LCAA-CPG) is presented. This... 
Nucleosides - chemical synthesis | Glass | Colorimetry | Receptor Aggregation | Succinates - chemical synthesis | Esters - chemical synthesis | Oligonucleotides - chemical synthesis
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 10/1995, Volume 23, Issue 19, pp. 3916 - 3921
The effects of 5-fluorouridine (FUrd) and 5-fluorodeoxyuridine (FdUrd) substitution on the stabilities of duplex RNA and DNA have been studied to determine how... 
BASE-STACKING | NMR | DEOXYRIBOOLIGONUCLEOTIDE | THERMODYNAMICS | MESSENGER-RNA | METABOLISM | KINETICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HELICES | MAGNETIC-RESONANCE | ANTICODON
Journal Article
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