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1. Full Text Genetically driven hyperglycemia increases risk of coronary artery disease separately from type 2 diabetes
by Merino, Jordi and Leong, Aaron and Posner, Daniel C and Porneala, Bianca and Masana, Lluís and Dupuis, Josée and Florez, Jose C
Diabetes care, ISSN 0149-5992, 05/2017, Volume 40, Issue 5, pp. 687 - 693
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Fasting | Humans | Risk Factors | Hyperglycemia - complications | Hyperglycemia - genetics | Diabetes Mellitus, Type 2 - blood | Mendelian Randomization Analysis | Coronary Artery Disease - epidemiology | Blood Glucose - metabolism | Odds Ratio | Diabetes Mellitus, Type 2 - complications | Type 2 diabetes | Complications and side effects | Hyperglycemia | Care and treatment | Coronary heart disease | Risk factors | Heart | Statistical analysis | Diabetes mellitus | Coronary artery | Health risks | Cardiovascular disease | Lipids | Genomes | Risk analysis | Coronary artery disease | Blood | Heterogeneity | Blood pressure | Research design | Diabetes | Heart diseases | Index Medicus | Cardiovascular and Metabolic Risk
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2. Full Text Tobacco-, alcohol-, and drug-attributable deaths and their contribution to mortality disparities in a cohort of homeless adults in Boston
by Baggett, Travis P and Chang, Yuchiao and Singer, Daniel E and Porneala, Bianca C and Gaeta, Jessie M and O'Connell, James J and Rigotti, Nancy A
American journal of public health (1971), ISSN 0090-0036, 06/2015, Volume 105, Issue 6, pp. 1189 - 1197
Life Sciences & Biomedicine | Public, Environmental & Occupational Health | Science & Technology | Homeless Persons - statistics & numerical data | Tobacco Use Disorder - mortality | Humans | Alcohol-Related Disorders - mortality | Drug Overdose - mortality | Boston - epidemiology | Adult | Female | Male | Substance-Related Disorders - mortality | Monte Carlo Method | Cause of Death | United States | Patient outcomes | Alcoholism | Medical care | Death | Management | Health aspects | Risk factors | Tobacco habit | Tobacco | Homeless people | Mortality | Lung cancer | Deaths | Behavior | Drug overdose | Addictions | Drug use | Smoking | Alcohol use | Index Medicus | Abridged Index Medicus | Drugs | Homelessness | Research and Practice | Alcohol | Epidemiology
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3. Full Text 757-P: Intensive Lifestyle Intervention for Diabetes Patients with Food Insecurity: A Preplanned Subgroup Analysis of the REAL HEALTH Randomized Clinical Trial (RCT)
by BERKOWITZ, SETH and WEXLER, DEBORAH J and CHANG, YUCHIAO and PORNEALA, BIANCA C and DELAHANTY, LINDA M
Diabetes (New York, N.Y.), ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 757
Intervention | Diabetes mellitus | Food security | Clinical trials | Body weight loss | Lifestyles | Diabetes | Diabetes mellitus (non-insulin dependent) | Patients
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4. Full Text Metabolite traits and genetic risk provide complementary information for the prediction of future type 2 diabetes
by Walford, Geoffrey A and Porneala, Bianca C and Dauriz, Marco and Vassy, Jason L and Cheng, Susan and Rhee, Eugene P and Wang, Thomas J and Meigs, James B and Gerszten, Robert E and Florez, Jose C
Diabetes care, ISSN 0149-5992, 2014, Volume 37, Issue 9, pp. 2508 - 2514
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Diabetes. Impaired glucose tolerance | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Metabolic diseases | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Genetic Predisposition to Disease | Area Under Curve | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Risk Factors | Logistic Models | Male | Metabolome - genetics | Diabetes Mellitus, Type 2 - diagnosis | Phenotype | Polymorphism, Single Nucleotide - genetics | Female | Odds Ratio | Type 2 diabetes | Metabolites | Analysis | Genetic aspects | Research | Single nucleotide polymorphisms | Biological markers | Risk factors | Biomarkers | Genetics | Accuracy | Diabetes | Index Medicus | Epidemiology | Health Services Research
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5. Full Text Polygenic type 2 diabetes prediction at the limit of common variant detection
by Vassy, Jason L and Hivert, Marie-France and Porneala, Bianca and Dauriz, Marco and Florez, Jose C and Dupuis, Josée and Siscovick, David S and Fornage, Myriam and Rasmussen-Torvik, Laura J and Bouchard, Claude and Meigs, James B
Diabetes (New York, N.Y.), ISSN 0012-1797, 2014, Volume 63, Issue 6, pp. 2172 - 2182
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Prospective Studies | Follow-Up Studies | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Child, Preschool | Male | Sedentary Lifestyle | Obesity - genetics | Diabetes Mellitus, Type 2 - epidemiology | Genetic Variation | Adult | Female | Child | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Obesity - complications | Risk Factors | Proportional Hazards Models | African Americans - genetics | Genotype | Environmental Exposure | Adolescent | Insulin Resistance - genetics | Aged | Polymorphism, Single Nucleotide | Type 2 diabetes | Genome-wide association studies | Usage | Analysis | Risk assessment | Multifactorial traits | Insulin resistance | Genetic aspects | Research | Statistics | Risk factors | Genotype & phenotype | Genomes | Diabetes | Index Medicus | Abridged Index Medicus | Metabolomics | Genetics | Proteomics
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6. Full Text Type 2 diabetes genetic predisposition, obesity, and all-cause mortality risk in the U.S.: A multiethnic analysis
by Leong, Aaron and Porneala, Bianca and Dupuis, Josée and Florez, Jose C and Meigs, James B
Diabetes care, ISSN 0149-5992, 04/2016, Volume 39, Issue 4, pp. 539 - 546
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Body Mass Index | United States - epidemiology | Genetic Predisposition to Disease | Prevalence | Follow-Up Studies | Diabetes Mellitus, Type 2 - genetics | Humans | Risk Factors | Neoplasms - mortality | Logistic Models | Male | Genotyping Techniques | Cardiovascular Diseases - genetics | Obesity - genetics | Socioeconomic Factors | Ethnic Groups - genetics | Neoplasms - genetics | Diabetes Mellitus, Type 2 - mortality | Alleles | Cardiovascular Diseases - mortality | Adult | Female | Polymorphism, Single Nucleotide | Obesity - mortality | Type 2 diabetes | Obesity | Care and treatment | United States | Mortality | Analysis | Single nucleotide polymorphisms | Research | Health aspects | Body mass index | Diabetes | Regression analysis | Risk assessment | Index Medicus | Epidemiology | Health Services Research
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7. Full Text Metabolomics insights into early type 2 diabetes pathogenesis and detection in individuals with normal fasting glucose
by Merino, Jordi and Leong, Aaron and Liu, Ching-Ti and Porneala, Bianca and Walford, Geoffrey A and von Grotthuss, Marcin and Wang, Thomas J and Flannick, Jason and Dupuis, Josée and Levy, Daniel and Gerszten, Robert E and Florez, Jose C and Meigs, James B
Diabetologia, ISSN 0012-186X, 6/2018, Volume 61, Issue 6, pp. 1315 - 1324
Metabolomics | Type 2 diabetes prediction | Type 2 diabetes pathophysiology | Medicine & Public Health | Human Physiology | Metabolic Diseases | Internal Medicine | Normoglycaemia | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Glycine - metabolism | Phenylalanine - metabolism | Prospective Studies | Area Under Curve | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Risk Factors | Computational Biology | Male | Diabetes Mellitus, Type 2 - metabolism | Incidence | Tandem Mass Spectrometry | Diabetes Mellitus, Type 2 - blood | Mendelian Randomization Analysis | Adult | Female | ROC Curve | Aged | Blood Glucose - metabolism | Taurine - metabolism | Type 2 diabetes | Metabolites | Analysis | Development and progression | Glucose | Medical screening | Glycine | Dextrose | Taurine | Fasting | Phenylalanine | Diabetes mellitus | Population studies | Regression analysis | Metabolism | Risk factors | Classification | Diabetes | Health risk assessment | Diabetes mellitus (non-insulin dependent) | Quantitative analysis | Index Medicus
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8. Full Text 2263-PUB: Consideration of Insulin Resistance Improves HbA1c-Based Type 2 Diabetes Risk Assessment
by MEIGS, JAMES B and PORNEALA, BIANCA C and LEONG, AARON and SHIFFMAN, DOV and DEVLIN, JAMES and MCPHAUL, MICHAEL J
Diabetes (New York, N.Y.), ISSN 0012-1797, 06/2020, Volume 69, Issue Supplement 1, p. 2263
Homeostasis | Insulin resistance | Fasting | Diabetes mellitus (non-insulin dependent) | Insulin | Risk assessment
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9. Full Text 240-OR: Combining Type 2 Diabetes Polygenic Scores Improves Prediction in 36,000 European and Non-European Participants in the Partners Healthcare Biobank
by MERCADER, JOSEP M and FLOREZ, JOSE C and LEONG, AARON and KAUR, VARINDERPAL and UDLER, MIRIAM and MEIGS, JAMES B and PORNEALA, BIANCA
Diabetes (New York, N.Y.), ISSN 0012-1797, 06/2020, Volume 69, Issue Supplement 1, p. 240
Genetic variance | Linkage disequilibrium | Biobanks | Predictions | Genomes | Diabetes | Diabetes mellitus (non-insulin dependent)
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10. Full Text Effectiveness of Lifestyle Intervention for Type 2 Diabetes in Primary Care: the REAL HEALTH-Diabetes Randomized Clinical Trial
by Delahanty, Linda M and Levy, Douglas E and Chang, Yuchiao and Porneala, Bianca C and Goldman, Valerie and McCarthy, Jeanna and Bissett, Laurie and Rodriguez, Anthony Romeo and Chase, Barbara and LaRocca, Rajani and Wheeler, Amy and Wexler, Deborah J
Journal of general internal medicine : JGIM, ISSN 0884-8734, 09/2020, Volume 35, Issue 9, pp. 2637 - 2646
Health Care Sciences & Services | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Type 2 diabetes | Clinical trials | Community health services | Diabetes therapy | Health care | Statistical analysis | Nutrition | Diabetes mellitus | Weight loss | Health centres | Body weight loss | Diabetes | Diabetes mellitus (non-insulin dependent) | Primary care | Patients | Index Medicus
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11. Full Text Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin
by Liu, Ching-Ti and Raghavan, Sridharan and Maruthur, Nisa and Kabagambe, Edmond Kato and Hong, Jaeyoung and Ng, Maggie C.Y and Hivert, Marie-France and Lu, Yingchang and An, Ping and Bentley, Amy R and Drolet, Anne M and Gaulton, Kyle J and Guo, Xiuqing and Armstrong, Loren L and Irvin, Marguerite R and Li, Man and Lipovich, Leonard and Rybin, Denis V and Taylor, Kent D and Agyemang, Charles and Palmer, Nicholette D and Cade, Brian E and Chen, Wei-Min and Dauriz, Marco and Delaney, Joseph A.C and Edwards, Todd L and Evans, Daniel S and Evans, Michele K and Lange, Leslie A and Leong, Aaron and Liu, Jingmin and Liu, Yongmei and Nayak, Uma and Patel, Sanjay R and Porneala, Bianca C and Rasmussen-Torvik, Laura J and Snijder, Marieke B and Stallings, Sarah C and Tanaka, Toshiko and Yanek, Lisa R and Zhao, Wei and Becker, Diane M and Bielak, Lawrence F and Biggs, Mary L and Bottinger, Erwin P and Bowden, Donald W and Chen, Guanjie and Correa, Adolfo and Couper, David J and Crawford, Dana C and Cushman, Mary and Eicher, John D and Fornage, Myriam and Franceschini, Nora and Fu, Yi-Ping and Goodarzi, Mark O and Gottesman, Omri and Hara, Kazuo and Harris, Tamara B and Jensen, Richard A and Johnson, Andrew D and Jhun, Min A and Karter, Andrew J and Keller, Margaux F and Kho, Abel N and Kizer, Jorge R and Krauss, Ronald M and Langefeld, Carl D and Li, Xiaohui and Liang, Jingling and Liu, Simin and Lowe, William L and Mosley, Thomas H and North, Kari E and Pacheco, Jennifer A and Peyser, Patricia A and Patrick, Alan L and Rice, Kenneth M and Selvin, Elizabeth and Sims, Mario and Smith, Jennifer A and Tajuddin, Salman M and Vaidya, Dhananjay and Wren, Mary P and Yao, Jie and Zhu, Xiaofeng and Ziegler, Julie T and Zmuda, Joseph M and Zonderman, Alan B and Zwinderman, Aeilko H and Adeyemo, Adebowale and Boerwinkle, Eric and Ferrucci, Luigi and Hayes, M. Geoffrey and Kardia, Sharon L.R and Miljkovic, Iva and Pankow, James S and Rotimi, Charles N and Sale, Michele M and Wagenknecht, Lynne E and ... and MEDIA Consortium and COGENT-BP Consortium and AAAG Consortium and eMERGE Consortium and MAGIC Consortium and CARe Consortium
American journal of human genetics, ISSN 0002-9297, 07/2016, Volume 99, Issue 1, pp. 56 - 75
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | European Continental Ancestry Group - genetics | Gene Frequency - genetics | Genome-Wide Association Study | Introns - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Molecular Sequence Annotation | Asian Continental Ancestry Group - genetics | Male | Continental Population Groups - genetics | Transcription Factors - metabolism | Insulin - metabolism | Ethnic Groups - genetics | Islets of Langerhans - metabolism | Insulin Resistance - genetics | Polymorphism, Single Nucleotide - genetics | Blood Glucose - genetics | Female | Enhancer Elements, Genetic - genetics | African Continental Ancestry Group - genetics | Fasting - metabolism | Quantitative Trait Loci - genetics | Genetic aspects | Glucose | Gene expression | Observations | Insulin | Dextrose | Genetics | Diabetes | Genomics | Meta-analysis | Index Medicus
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