Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (201) 201
humans (193) 193
female (120) 120
male (119) 119
genetics & heredity (98) 98
neurosciences (86) 86
adult (82) 82
genetics (80) 80
genome-wide association study (71) 71
research (68) 68
schizophrenia (66) 66
genetic aspects (61) 61
genomes (61) 61
heritability (58) 58
psychiatry (57) 57
genome-wide association (56) 56
genomics (55) 55
genes (53) 53
phenotype (51) 51
middle aged (49) 49
article (48) 48
polymorphism, single nucleotide (48) 48
adolescent (46) 46
intelligence (45) 45
genetic predisposition to disease (43) 43
child (41) 41
analysis (40) 40
risk factors (40) 40
studies (40) 40
twins (39) 39
mental disorders (37) 37
genotype (36) 36
gene expression (33) 33
risk (33) 33
genetic variation (32) 32
loci (32) 32
schizophrenia - genetics (32) 32
aged (29) 29
behavioral sciences (29) 29
human genetics (29) 29
netherlands (29) 29
polymorphism, single nucleotide - genetics (29) 29
psychology, multidisciplinary (29) 29
case-control studies (28) 28
children (28) 28
psychology (28) 28
association (27) 27
cohort studies (27) 27
consortia (27) 27
metaanalysis (27) 27
brain (26) 26
meta-analysis (26) 26
variants (25) 25
bipolar disorder (23) 23
gwas (23) 23
multidisciplinary sciences (23) 23
cognition (22) 22
environment (22) 22
genetic research (22) 22
twin (22) 22
biochemistry & molecular biology (21) 21
population (21) 21
single nucleotide polymorphisms (21) 21
intelligence - genetics (20) 20
health aspects (19) 19
medicin och hälsovetenskap (19) 19
models, genetic (19) 19
quantitative trait loci (19) 19
usage (19) 19
alleles (18) 18
autism (18) 18
cognitive ability (18) 18
disease (18) 18
genome-wide association studies (18) 18
genome-wide association study - methods (18) 18
linkage (18) 18
phenotypes (18) 18
traits (18) 18
twins, dizygotic - genetics (18) 18
twins, monozygotic - genetics (18) 18
young adult (18) 18
clinical neurology (17) 17
medical and health sciences (17) 17
biology (16) 16
genetic predisposition to disease - genetics (16) 16
genome, human (16) 16
power (16) 16
single-nucleotide polymorphism (16) 16
abridged index medicus (15) 15
age (15) 15
computer simulation (15) 15
disorders (15) 15
epidemiology (15) 15
evolutionary biology (15) 15
siblings (15) 15
family (14) 14
genotype & phenotype (14) 14
methods (14) 14
physiological aspects (14) 14
public health/gesundheitswesen (14) 14
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Analysis of shared heritability in common disorders of the brain
by Anttila, Verneri and Bulik-Sullivan, Brendan and Finucane, Hilary K and Walters, Raymond K and Bras, Jose and Duncan, Laramie and Escott-Price, Valentina and Falcone, Guido J and Gormley, Padhraig and Malik, Rainer and Patsopoulos, Nikolaos A and Ripke, Stephan and Wei, Zhi and Yu, Dongmei and Lee, Phil H and Turley, Patrick and Grenier-Boley, Benjamin and Chouraki, Vincent and Kamatani, Yoichiro and Berr, Claudine and Letenneur, Luc and Hannequin, Didier and Amouyel, Philippe and Boland, Anne and Deleuze, Jean-François and Duron, Emmanuelle and Vardarajan, Badri N and Reitz, Christiane and Goate, Alison M and Huentelman, Matthew J and Ilyas Kamboh, M and Larson, Eric B and Rogaeva, Ekaterina and George-Hyslop, Peter St and Hakonarson, Hakon and Kukull, Walter A and Farrer, Lindsay A and Barnes, Lisa L and Beach, Thomas G and Yesim Demirci, F and Head, Elizabeth and Hulette, Christine M and Jicha, Gregory A and Kauwe, John S.K and Kaye, Jeffrey A and Leverenz, James B and Levey, Allan I and Lieberman, Andrew P and Pankratz, Vernon S and Poon, Wayne W and Quinn, Joseph F and Saykin, Andrew J and Schneider, Lon S and Smith, Amanda G and Sonnen, Joshua A and Stern, Robert A and Van Deerlin, Vivianna M and Van Eldik, Linda J and Harold, Denise and Russo, Giancarlo and Rubinsztein, David C and Bayer, Anthony and Tsolaki, Magda and Proitsi, Petra and Fox, Nick C and Hampel, Harald and Owen, Michael J and Mead, Simon and Passmore, Peter and Morgan, Kevin and Nöthen, Markus M and Rossor, Martin and Lupton, Michelle K and Hoffmann, Per and Kornhuber, Johannes and Lawlor, Brian and McQuillin, Andrew and Al-Chalabi, Ammar and Bis, Joshua C and Ruiz, Agustin and Boada, Mercè and Seshadri, Sudha and Beiser, Alexa and Rice, Kenneth and Van Der Lee, Sven J and De Jager, Philip L and Geschwind, Daniel H and Riemenschneider, Matthias and Riedel-Heller, Steffi and Rotter, Jerome I and Ransmayr, Gerhard and Hyman, Bradley T and Cruchaga, Carlos and Alegret, Montserrat and Winsvold, Bendik and Palta, Priit and Farh, Kai-How and Cuenca-Leon, Ester and Furlotte, Nicholas and Kurth, Tobias and ... and Brainstorm Consortium and The Brainstorm Consortium
Science, ISSN 0036-8075, 06/2018, Volume 360, Issue 6395, pp. 1313 - 1313
Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We... 
ANOREXIA-NERVOSA | POPULATION-BASED TWIN | DEFICIT HYPERACTIVITY DISORDER | LONG-TERM SURVIVAL | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | GENETIC CORRELATIONS | BODY-MASS INDEX | MAJOR DEPRESSIVE DISORDER | BIPOLAR DISORDER | GENOME-WIDE ASSOCIATION | Genetic Variation | Mental Disorders - genetics | Genome-Wide Association Study | Phenotype | Brain Diseases - classification | Quantitative Trait, Heritable | Brain Diseases - diagnosis | Humans | Mental Disorders - classification | Risk Factors | Brain Diseases - genetics | Mental Disorders - diagnosis | Anorexia | Disorders | Cognitive ability | Bipolar disorder | Posttraumatic stress disorder | Mental depression | Epidemiology | Risk factors | Consortia | Proteins | Ischemia | Etiology | Classification | Gilles de la Tourette syndrome | Alzheimer's disease | Neurological disorders | Neurodegenerative diseases | Comorbidity | Behavior disorders | Anorexia nervosa | Risk analysis | Patients | Neurological diseases | Correlation analysis | Heritability | Attention deficit disorder | Headache | Mental disorders | Medical services | Schizophrenia | Risk sharing | Genomes | Heterogeneity | Biological effects | Risk assessment | Stroke | Phenotypes | Migraine | Attention deficit hyperactivity disorder | Eating disorders | Personality | Genetic diversity | Statistics | Activity patterns | Crohn's Disease | Population (statistical) | Scaffolding | Diagnostic systems | Alzheimers disease | Index Medicus | Life Sciences | Human health and pathology | Mental Disorders | Neurons and Cognition | Brain Diseases | Genetics
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture
by Davis, Lea K and Yu, Dongmei and Keenan, Clare L and Gamazon, Eric R and Konkashbaev, Anuar I and Derks, Eske M and Neale, Benjamin M and Yang, Jian and Lee, S. Hong and Evans, Patrick and Barr, Cathy L and Bellodi, Laura and Benarroch, Fortu and Berrio, Gabriel Bedoya and Bienvenu, Oscar J and Bloch, Michael H and Blom, Rianne M and Bruun, Ruth D and Budman, Cathy L and Camarena, Beatriz and Campbell, Desmond and Cappi, Carolina and Cardona Silgado, Julio C and Cath, Danielle C and Cavallini, Maria C and Chavira, Denise A and Chouinard, Sylvain and Conti, David V and Cook, Edwin H and Coric, Vladimir and Cullen, Bernadette A and Deforce, Dieter and Delorme, Richard and Dion, Yves and Edlund, Christopher K and Egberts, Karin and Falkai, Peter and Fernandez, Thomas V and Gallagher, Patience J and Garrido, Helena and Geller, Daniel and Girard, Simon L and Grabe, Hans J and Grados, Marco A and Greenberg, Benjamin D and Gross-Tsur, Varda and Haddad, Stephen and Heiman, Gary A and Hemmings, Sian M. J and Hounie, Ana G and Illmann, Cornelia and Jankovic, Joseph and Jenike, Michael A and Kennedy, James L and King, Robert A and Kremeyer, Barbara and Kurlan, Roger and Lanzagorta, Nuria and Leboyer, Marion and Leckman, James F and Lennertz, Leonhard and Liu, Chunyu and Lochner, Christine and Lowe, Thomas L and Macciardi, Fabio and McCracken, James T and McGrath, Lauren M and Mesa Restrepo, Sana C and Moessner, Rainald and Morgan, Jubel and Muller, Heike and Murphy, Dennis L and Naarden, Allan L and Ochoa, William Cornejo and Ophoff, Roel A and Osiecki, Lisa and Pakstis, Anew J and Pato, Michele T and Pato, Carlos N and Piacentini, John and Pittenger, Christopher and Pollak, Yehuda and Rauch, Scott L and Renner, Tobias J and Reus, Victor I and Richter, Margaret A and Riddle, Mark A and Robertson, Mary M and Romero, Roxana and Rosàrio, Maria C and Rosenberg, David and Rouleau, Guy A and Ruhrmann, Stephan and Ruiz-Linares, Anes and Sampaio, Aline S and Samuels, Jack and Sandor, Paul and Sheppard, Brooke and Singer, Harvey S and Smit, Jan H and ...
PLoS genetics, ISSN 1553-7390, 2013, Volume 9, Issue 10, pp. e1003864 - e1003864
The direct estimation of heritability from genome-wide common variant data as implemented in the program Genome-wide Complex Trait Analysis (GCTA) has provided... 
GILLES | SCHOOL | AUTISM | NEUROPSYCHIATRIC DISORDERS | GENETICS & HEREDITY | MISSING HERITABILITY | RISK | TIC DISORDERS | PREVALENCE | EXPRESSION | FAMILY | Tourette Syndrome - genetics | Obsessive-Compulsive Disorder - genetics | Genome-Wide Association Study | Phenotype | Quantitative Trait, Heritable | Tourette Syndrome - pathology | Gene Frequency | Humans | Obsessive-Compulsive Disorder - pathology | Polymorphism, Single Nucleotide | Tourette's syndrome | Neurogenetics | Physiological aspects | Genetic aspects | Obsessive-compulsive disorder | Research | Cell differentiation | Index Medicus | Architecture | Alcoholism | Genomes | Gene expression | Estimates | Risk factors | Studies | Brain research | Neuroses | Genetics | Tourette syndrome | Health risk assessment | Chromosomes | Child & adolescent psychiatry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Copy Number Variation in Obsessive-Compulsive Disorder and Tourette Syndrome: A Cross-Disorder Study
by McGrath, Lauren M., PhD and Yu, Dongmei, MS and Marshall, Christian, PhD and Davis, Lea K., PhD and Thiruvahindrapuram, Bhooma, MSc and Li, Bingbin, HBSc and Cappi, Carolina, MSc and Gerber, Gloria, BA and Wolf, Aaron, BA and Schroeder, Frederick A., PhD and Osiecki, Lisa, BA and O'Dushlaine, Colm, PhD and Kirby, Andrew, BA and Illmann, Cornelia, PhD and Haddad, Stephen, MS and Gallagher, Patience, BS and Fagerness, Jesen A., JD and Barr, Cathy L., PhD and Bellodi, Laura, MD and Benarroch, Fortu, MD and Bienvenu, O. Joseph, MD, PhD and Black, Donald W., MD and Bloch, Michael H., MD, MS and Bruun, Ruth D., MD and Budman, Cathy L., MD and Camarena, Beatriz, MSc and Cath, Danielle C., MD and Cavallini, Maria C., MD and Chouinard, Sylvain, MD and Coric, Vladimir, MD and Cullen, Bernadette, MB, BCh. BAO and Delorme, Richard, MD, PhD and Denys, Damiaan, MD, PhD and Derks, Eske M., PhD and Dion, Yves, MD and Rosário, Maria C., MD, PhD and Eapen, Valsama, MD, PhD and Evans, Patrick, PhD and Falkai, Peter, MD and Fernandez, Thomas V., MD and Garrido, Helena, MA and Geller, Daniel, MD and Grabe, Hans J., MD and Grados, Marco A., MD, MPH and Greenberg, Benjamin D., MD, PhD and Gross-Tsur, Varda, MD and Grünblatt, Edna, PhD and Heiman, Gary A., PhD and Hemmings, Sian M.J., PhD and Herrera, Luis D., MD, MPH and Hounie, Ana G., MD, PhD and Jankovic, Joseph, MD and Kennedy, James L., MD and King, Robert A., MD and Kurlan, Roger, MD and Lanzagorta, Nuria, PsyD and Leboyer, Marion, MD, PhD and Leckman, James F., MD and Lennertz, Leonhard, MSc and Lochner, Christine, PhD and Lowe, Thomas L., MD and Lyon, Gholson J., MD, PhD and Macciardi, Fabio, MD, PhD and Maier, Wolfgang, MD and McCracken, James T., MD and McMahon, William, MD and Murphy, Dennis L., MD and Naarden, Allan L., MD and Neale, Benjamin M., PhD and Nurmi, Erika, MD, PhD and Pakstis, Andrew J., PhD and Pato, Michele T., MD and Pato, Carlos N., MD, PhD and Piacentini, John, PhD and Pittenger, Christopher, MD, PhD and Pollak, Yehuda, PhD and Reus, Victor I., MD and Richter, Margaret A., MD and Riddle, Mark, MD and Robertson, Mary M., MD, PhD and Rosenberg, David, MD and Rouleau, Guy A., MD and Ruhrmann, Stephan, MD and Sampaio, Aline S., MD, PhD and Samuels, Jack, PhD and Sandor, Paul, MD and Sheppard, Brooke, MSc and Singer, Harvey S., MD and Smit, Jan H., PhD and Stein, Dan J., MD, PhD and Tischfield, Jay A., PhD and Vallada, Homero, MD, PhD and Veenstra-VanderWeele, Jeremy, MD and Walitza, Susanne, MD and Wang, Ying, MSc and Wendland, Jens R., MD and Shugart, Yin Yao, PhD and Miguel, Euripedes C., MD, PhD and Nicolini, Humberto, MD, PhD and Oostra, Ben A., PhD and ...
Journal of the American Academy of Child & Adolescent Psychiatry, ISSN 0890-8567, 2014, Volume 53, Issue 8, pp. 910 - 919
Objective Obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) are heritable neurodevelopmental disorders with a partially shared genetic etiology.... 
Pediatrics | Psychiatry | 16p13.11 | genetics | copy number variation | Tourette syndrome | obsessive-compulsive disorder | DUPLICATIONS | AUTISM | 16P13.11 PREDISPOSE | VARIANTS | PSYCHIATRY | RARE CHROMOSOMAL DELETIONS | PSYCHOLOGY, DEVELOPMENTAL | SCHIZOPHRENIA | DEVELOPMENTAL-DISABILITIES | PEDIATRICS | DE-NOVO CNVS | GENOME-WIDE ASSOCIATION | Tourette Syndrome - genetics | Diagnostic and Statistical Manual of Mental Disorders | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Male | Tourette Syndrome - diagnosis | DNA Copy Number Variations | Obsessive-Compulsive Disorder - genetics | Obsessive-Compulsive Disorder - diagnosis | Adolescent | Female | Polymorphism, Single Nucleotide | Tourette's syndrome | Obsessive-compulsive disorder | Genetic aspects | Neurology | Genotype & phenotype | Neuroses | Genomics | Neuropsychology | Psychopathology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text PGC Data Access Committee: Methods To Access PGC Data
by Posthuma, Danielle
European Neuropsychopharmacology, ISSN 0924-977X, 2019, Volume 29, pp. S713 - S713
Overall Abstract 
PHARMACOLOGY & PHARMACY | PSYCHIATRY | NEUROSCIENCES | CLINICAL NEUROLOGY
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Using The Lisa Genetic Cluster
by Posthuma, Danielle
European Neuropsychopharmacology, ISSN 0924-977X, 2019, Volume 29, pp. S713 - S713
Through the PGC-DAC portal PGC users obtain access to PGC-related phenotypic and genetic data. All PGC data is stored on the Dutch Genetic Cluster Computer,... 
PHARMACOLOGY & PHARMACY | PSYCHIATRY | NEUROSCIENCES | CLINICAL NEUROLOGY
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Functional mapping and annotation of genetic associations with FUMA
by Watanabe, Kyoko and Taskesen, Erdogan and Van Bochoven, Arjen and Posthuma, Danielle
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1826 - 11
A main challenge in genome-wide association studies (GWAS) is to pinpoint possible causal variants. Results from GWAS typically do not directly translate into... 
HUMAN BRAIN | GWAS | CROHNS-DISEASE | VARIANTS | MULTIDISCIPLINARY SCIENCES | SCHIZOPHRENIA | LOCI | CAPTURE HI-C | ACETYLCHOLINE-RECEPTOR | DISCOVERY | GENOME-WIDE ASSOCIATION | Crohn Disease - genetics | Computational Biology - methods | Genetic Predisposition to Disease | Genome-Wide Association Study - instrumentation | Humans | Databases, Genetic | Molecular Sequence Annotation - methods | Chromosome Mapping - instrumentation | Linkage Disequilibrium | Chromosome Mapping - methods | Internet | Genome, Human | Genome-Wide Association Study - methods | Quantitative Trait Loci | Chromatin - genetics | Chromatin | Visual aids | Linkage disequilibrium | Genomes | Gene expression | Data interpretation | Quantitative trait loci | Genotype & phenotype | Biological effects | Annotations | Coding | Gene loci | Gene mapping | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
by Savage, Jeanne E and Jansen, Philip R and Stringer, Sven and Watanabe, Kyoko and Bryois, Julien and De Leeuw, Christiaan A and Nagel, Mats and Awasthi, Swapnil and Barr, Peter B and Coleman, Jonathan R. I and Grasby, Katrina L and Hammerschlag, Anke R and Kaminski, Jakob A and Karlsson, Robert and Krapohl, Eva and Lam, Max and Nygaard, Marianne and Reynolds, Chandra A and Trampush, Joey W and Young, Hannah and Zabaneh, Delilah and Hägg, Sara and Hansell, Narelle K and Karlsson, Ida K and Linnarsson, Sten and Montgomery, Grant W and Muñoz-Manchado, Ana B and Quinlan, Erin B and Schumann, Gunter and Skene, Nathan G and Webb, Bradley T and White, Tonya and Arking, Dan E and Avramopoulos, Dimitrios and Bilder, Robert M and Bitsios, Panos and Burdick, Katherine E and Cannon, Tyrone D and Chiba-Falek, Ornit and Christoforou, Andrea and Cirulli, Elizabeth T and Congdon, Eliza and Corvin, Aiden and Davies, Gail and Deary, Ian J and Derosse, Pamela and Dickinson, Dwight and Djurovic, Srdjan and Donohoe, Gary and Conley, Emily Drabant and Eriksson, Johan G and Espeseth, Thomas and Freimer, Nelson A and Giakoumaki, Stella and Giegling, Ina and Gill, Michael and Glahn, David C and Hariri, Ahmad R and Hatzimanolis, Alex and Keller, Matthew C and Knowles, Emma and Koltai, Deborah and Konte, Bettina and Lahti, Jari and Le Hellard, Stephanie and Lencz, Todd and Liewald, David C and London, Edythe and Lundervold, Astri J and Malhotra, Anil K and Melle, Ingrid and Morris, Derek and Need, Anna C and Ollier, William and Palotie, Aarno and Payton, Antony and Pendleton, Neil and Poldrack, Russell A and Räikkönen, Katri and Reinvang, Ivar and Roussos, Panos and Rujescu, Dan and Sabb, Fred W and Scult, Matthew A and Smeland, Olav B and Smyrnis, Nikolaos and Starr, John M and Steen, Vidar M and Stefanis, Nikos C and Straub, Richard E and Sundet, Kjetil and Tiemeier, Henning and Voineskos, Aristotle N and Weinberger, Daniel R and Widen, Elisabeth and Yu, Jin and Abecasis, Goncalo and Andreassen, Ole A and Breen, Gerome and Christiansen, Lene and ...
Nature Genetics, ISSN 1061-4036, 07/2018, Volume 50, Issue 7, pp. 912 - 919
Intelligence is highly heritable(1) and a major determinant of human health and well-being(2). Recent genome-wide meta-analyses have identified 24 genomic loci... 
GENERAL COGNITIVE FUNCTION | CONSORTIUM | TEST BATTERIES | GWAS | ANNOTATION | GENETICS & HEREDITY | RISK | LOCI | EDUCATIONAL-ATTAINMENT | TRAITS | HERITABILITY | Genetic Predisposition to Disease | Humans | Middle Aged | Adolescent | Female | Male | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Intelligence - genetics | Quantitative Trait Loci | Brain - physiology | Brain | Chromatin | Neurosciences | Intelligence | Synaptogenesis | Mental disorders | Genomics | Genes | Cognitive ability | Schizophrenia | Association analysis | Nervous system | Identification | Mapping | Genomes | Genetic effects | Annotations | Coding | Genetic analysis | Neostriatum | Alzheimer's disease | Bioinformatics | Neurodegenerative diseases | Neurons | Attention deficit hyperactivity disorder | Causation | Gene expression | Spiny neurons | Loci | Educational attainment | Meta-analysis | Quantitative trait loci | Neurological diseases | Studies | Pyramidal cells | Gene loci | Gene mapping | Alzheimers disease | Hippocampus | Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | Alzheimer disease | Article | nervous system development | genetic association | gene location | schizophrenia | Klinisk medicin | pleiotropy | gene mapping | genetic correlation | priority journal | human | Neurologi | corpus striatum | hippocampus | synapse | chromatin | heredity | genetic variability | intelligence | pyramidal nerve cell | gene locus | Mendelian randomization analysis | Clinical Medicine | Neurology | expression quantitative trait locus | medium spiny neuron | genome-wide association study | attention deficit disorder | exon | conserved sequence | gene expression
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Meta-analysis of the heritability of human traits based on fifty years of twin studies
by Polderman, T.J.C and Benyamin, B and Leeuw, C.A. de and Sullivan, P.F and Bochoven, A. van and Visscher, P.M and Posthuma, D
Nature Genetics, ISSN 1061-4036, 2015, Volume 47, Issue 7, pp. 702 - +
Despite a century of research on complex traits in humans, the relative importance and specific nature of the influences of genes and environment on human... 
MISSING HERITABILITY | DISEASES | RELATIVES | EPISTASIS | BIAS | GENETICS & HEREDITY | Genetic Predisposition to Disease | Genetic Association Studies | Twins, Monozygotic - genetics | Humans | Models, Genetic | Gene-Environment Interaction | Genetic Heterogeneity | Twins, Dizygotic - genetics | Cluster Analysis | Chromosome mapping | Genetic variation | Innovations | Genetic aspects | Heritability | Twins | Identification and classification | Studies | Design | Sample size | Authorship | Genes | Older people | Classification | Population | Research | Metabolism | Estimates | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text MAGMA: Generalized Gene-Set Analysis of GWAS Data
by Leeuw, C.A. de and Mooij, J.M and Heskes, T and Posthuma, D
PLoS Computational Biology, ISSN 1553-7358, 2015, Volume 11, Issue 4, pp. e1004219 - e1004219
By aggregating data for complex traits in a biologically meaningful way, gene and gene-set analysis constitute a valuable addition to single-marker analysis.... 
DISEASES | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | SCHIZOPHRENIA | COMMON | LOCI | ENRICHMENT ANALYSIS | GENOME-WIDE ASSOCIATION | Crohn Disease - genetics | Computational Biology - methods | Computer Simulation | Humans | Databases, Genetic | Models, Genetic | Software | Genome-Wide Association Study - methods | Index Medicus | Competition | Simulation | Genes | Statistics | Magma | Methods | Crohns disease
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome
by Huang, Alden Y and Yu, Dongmei and Davis, Lea K and Sul, Jae Hoon and Tsetsos, Fotis and Ramensky, Vasily and Zelaya, Ivette and Ramos, Eliana Marisa and Osiecki, Lisa and Chen, Jason A and McGrath, Lauren M and Illmann, Cornelia and Sandor, Paul and Barr, Cathy L and Grados, Marco and Singer, Harvey S and Nöthen, Markus M and Hebebrand, Johannes and King, Robert A and Dion, Yves and Rouleau, Guy and Budman, Cathy L and Depienne, Christel and Worbe, Yulia and Hartmann, Andreas and Müller-Vahl, Kirsten R and Stuhrmann, Manfred and Aschauer, Harald and Stamenkovic, Mara and Schloegelhofer, Monika and Konstantinidis, Anastasios and Lyon, Gholson J and McMahon, William M and Barta, Csaba and Tarnok, Zsanett and Nagy, Peter and Batterson, James R and Rizzo, Renata and Cath, Danielle C and Wolanczyk, Tomasz and Berlin, Cheston and Malaty, Irene A and Okun, Michael S and Woods, Douglas W and Rees, Elliott and Pato, Michele T and Pato, Carlos N and Knowles, James A and Posthuma, Danielle and Pauls, David L and Cox, Nancy J and Neale, Benjamin M and Freimer, Nelson B and Paschou, Peristera and Mathews, Carol A and Scharf, Jeremiah M and Coppola, Giovanni and Bruun, Ruth D and Chouinard, Sylvain and Darrow, Sabrina and Greenberg, Erica and Hirschtritt, Matthew E and Kurlan, Roger and Leckman, James F and Robertson, Mary M and Smit, Jan and TSAICG and Gilles Tourette Syndrome GWAS and Tourette Syndrome Association International Consortium for Genetics (TSAICG) and Gilles de la Tourette Syndrome GWAS Replication Initiative (GGRI)
Neuron, ISSN 0896-6273, 06/2017, Volume 94, Issue 6, pp. 1101 - 1111.e7
Tourette syndrome (TS) is a model neuropsychiatric disorder thought to arise from abnormal development and/or maintenance of cortico-striato-thalamo-cortical... 
structural variation | genetics | copy number variation | CNTN6 | Tourette Syndrome | NRXN1 | tic disorders | neurodevelopmental disorders | SNP GENOTYPING DATA | GENETICS | HIDDEN-MARKOV MODEL | NEUREXINS | CHRONIC TIC DISORDERS | COHORT | PREVALENCE | ASSOCIATION | NEUROSCIENCES | OBSESSIVE-COMPULSIVE DISORDER | Tourette Syndrome - genetics | Contactins - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Genotype | Male | Nerve Tissue Proteins - genetics | Case-Control Studies | Cell Adhesion Molecules, Neuronal - genetics | DNA Copy Number Variations | Young Adult | Adolescent | Adult | Female | Odds Ratio | Child | Tourette's syndrome | Nervous system diseases | Genomics | Attention deficit disorder | Obsessive compulsive disorder | Working groups | Mental disorders | Copy number | Circuits | Genes | Cortex | Schizophrenia | Genomes | Single-nucleotide polymorphism | Cases (containers) | Loci | Studies | Consortia | Genetics | Gilles de la Tourette syndrome | Tourette syndrome | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights