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by Kato, Norihiro and Loh, Marie and Takeuchi, Fumihiko and Verweij, Niek and Wang, Xu and Zhang, Weihua and NKelly, Tanika and Saleheen, D and Lehne, Benjamin and Leach, Irene Mateo and ng, Alexander and Abbott, James and Wahl, Simone and Tan, Sian-Tsung and Scott, William R and Campanella, Gianluca and Chadeau-Hyam, Marc and Afzal, Uzma and Ahluwalia, Tarunveer Singh and Bonder, Marc and Chen, Ping and Dehghan, Abbas and Edwards, Todd L and Esko, Tõnu and Go, Min Jin and Harris, Sarah and Hartiala, Jaana and Kasela, Silva and Kasturiratne, Anuradhani and Khor, C.C and Kleber, Marcus and Li, Huaixing and Mok, Zuan Yu and Nakatochi, Masahiro and Sapari, Nur Sabrina and Saxena, Richa and Stewart, Alexane F and Stolk, Lisette and Tabara, Yasuharu and Teh, Ai Ling and Wu, Ying and Wu, Jer-Yuarn and Zhang, Yi and Aits, Imke and Da Silva Couto Alves, Alexessander and Das, Shikta and Dorajoo, Rajkumar and CHopewell, Jemma and Kim, Yun Kyoung and WKoivula, Robert and Luan, Jian'An and Lyytikäinen, Leo-Pekka and NNguyen, Quang and Pereira, Mark A and Postmus, Douwe and TRaitakari, Olli and Scannell Bryan, Molly and Scott, Robert and Sorice, R and Tragante, Vinicius and Traglia, Michela and White, Jon and Yamamoto, Ken and Zhang, Yonghong and Adair, Linda and Ahmed, Alauddin and Akiyama, Koichi and Asif, Rasheed and Aung, Tin and Barroso, Inês and Bjonnes, Anew and Braun, Timothy R and Cai, Hui and Chang, Li-Ching and Chen, C.-H and Cheng, Ching-Yu and Chong, Yap-Seng and Collins, Francis and Courtney, Regina and Davies, Gail and Delgado, G and Do, Loi D and Doevendans, Pieter and Gansevoort, Ron and Gao, Y and Grammer, Tanja B and Grarup, Niels and Grewal, Jagvir and Gu, D and SWander, Gurpreet and Hartikainen, A.L and Hazen, Stanley and He, Jing and Heng, Chew-Kiat and Hixso, E. James Ames and Hofman, Albert and Hsu, Chris and Huang, Wei and Husemoen, Lise Lotte and Hwang, Joo-Yeon and ... and InterAct Consortium and BIOS-consortium and LifeLines Cohort Study and CARDIo GRAMplusCD and The InterAct Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Umeå universitet
Nature Genetics, ISSN 1061-4036, 11/2015, Volume 47, Issue 11, pp. 1282 - 1293
textabstractWe carried out a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up to 320,251 individuals of East... 
INDIVIDUALS | CENTRIC ARRAY | RISK-FACTORS | METAANALYSIS | VARIANTS | PULMONARY ARTERIAL-HYPERTENSION | REGIONS | TISSUE | GENETICS & HEREDITY | CARDIOVASCULAR-DISEASE | KIDNEY | Cardiovascular Diseases - ethnology | Blood Pressure - genetics | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Genetic Loci - genetics | Male | Cardiovascular Diseases - genetics | Genetic Variation | DNA Methylation | Peptide Fragments - blood | Aged, 80 and over | Cardiovascular Diseases - blood | Adult | Female | Natriuretic Peptide, Brain - blood | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Risk Factors | Genotype | Regression Analysis | Genetic Predisposition to Disease - ethnology | Aged | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Blood pressure | Regulation | Genetic aspects | Single nucleotide polymorphisms | Gene expression | Identification and classification | Health aspects | Hypertension | Genealogy | Cardiovascular disease | Genomes | Genotype & phenotype | Womens health | DNA methylation | Population | Gene loci | Binding sites | Deoxyribonucleic acid--DNA | Asians | Index Medicus | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Postmus, Iris and Trompet, Stella and Deshmukh, Harshal A and Barnes, Michael R and Li, Xiaohui and Warren, Helen R and Chasman, Daniel I and Zhou, Kaixin and Arsenault, Benoit J and Donnelly, Louise A and Wiggins, Kerri L and Avery, Christy L and Griffin, Paula and Feng, QiPing and Taylor, Kent D and Li, Guo and Evans, Daniel S and Smith, Albert V and de Keyser, Catherine E and Johnson, Anew D and de Craen, Anton J. M and Stott, David J and Buckley, Brendan M and Ford, Ian and Westendorp, Rudi G. J and Slagboom, P. Eline and Sattar, Naveed and Munroe, Patricia B and Sever, Peter and Poulter, Neil and Stanton, Alice and Shields, Denis C and O'Brien, Eoin and Shaw-Hawkins, Sue and Chen, Y.-D. Ida and Nickerson, Deborah A and Smith, Joshua D and Dubé, Marie Pierre and Boekholdt, S. Matthijs and Hovingh, G. Kees and Kastelein, John J. P and McKeigue, Paul M and Betteridge, John and Neil, Anew and Durrington, Paul N and Doney, Alex and Carr, Fiona and Morris, Anew and McCarthy, Mark I and Groop, Leif and Ahlqvist, Emma and Bis, Joshua C and Rice, Kenneth and Smith, Nicholas L and Lumley, Thomas and Whitsel, Eric A and Stürmer, Til and Boerwinkle, Eric and Ngwa, Julius S and O'Donnell, Christopher J and Vasan, Ramachanan S and Wei, Wei-Qi and Wilke, Russell A and Liu, Ching-Ti and Sun, Fangui and Guo, Xiuqing and Heckbert, Susan R and Post, Wendy and Sotoodehnia, Nona and Arnold, Alice M and Stafford, Jeanette M and Ding, Jingzhong and Herrington, David M and Kritchevsky, Stephen B and Eiriksdottir, Gudny and Launer, Leonore J and Harris, Tamara B and Chu, Auey Y and Giulianini, Franco and Macfadyen, Jean G and Barratt, Bryan J and Nyberg, Freik and Stricker, Bruno H and Uitterlinden, Ané G and Hofman, Albert and Rivadeneira, Fernando and Emilsson, Valur and Franco, Oscar H and Ridker, Paul M and Gudnason, Vilmundur and Liu, Yongmei and Denny, Joshua C and Ballantyne, Christie M and Rotter, Jerome I and Aienne Cupples, L and Psaty, Bruce M and Palmer, Colin N. A and Tardif, Jean-Claude and Colhoun, Helen M and Hitman, Graham and ... and Welcome Trust Case Control Consort and Welcome Trust Case Control Consortium and Data and Analysis Group and DNA, Genotyping, Data QC and Informatics Group and Membership of Wellcome Trust Case Control Consortium and Publications Committee and Sahlgrenska akademin and Göteborgs universitet and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för arbets-och miljömedicin and Gothenburg University and Institute of Medicine, Department of Public Health and Community Medicine, Section of Occupational and environmental medicine and Sahlgrenska Academy
Nature communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5068 - 5068
Journal Article
by Postmus, Iris and Warren, Helen R and Trompet, Stella and Arsenault, Benoit J and Avery, Christy L and Bis, Joshua C and Chasman, Daniel I and de Keyser, Catherine E and Deshmukh, Harshal A and Evans, Daniel S and Feng, QiPing and Li, Xiaohui and Smit, Roelof A J and Smith, Albert V and Sun, Fangui and Taylor, Kent D and Arnold, Alice M and Barnes, Michael R and Barratt, Bryan J and Betteridge, John and Boekholdt, S Matthijs and Boerwinkle, Eric and Buckley, Brendan M and Chen, Y-D Ida and de Craen, Anton J M and Cummings, Steven R and Denny, Joshua C and Dubé, Marie Pierre and Durrington, Paul N and Eiriksdottir, Gudny and Ford, Ian and Guo, Xiuqing and Harris, Tamara B and Heckbert, Susan R and Hofman, Albert and Hovingh, G Kees and Kastelein, John J P and Launer, Leonore J and Liu, Ching-Ti and Liu, Yongmei and Lumley, Thomas and McKeigue, Paul M and Munroe, Patricia B and Neil, Andrew and Nickerson, Deborah A and Nyberg, Fredrik and O'Brien, Eoin and O'Donnell, Christopher J and Post, Wendy and Poulter, Neil and Vasan, Ramachandran S and Rice, Kenneth and Rich, Stephen S and Rivadeneira, Fernando and Sattar, Naveed and Sever, Peter and Shaw-Hawkins, Sue and Shields, Denis C and Slagboom, P Eline and Smith, Nicholas L and Smith, Joshua D and Sotoodehnia, Nona and Stanton, Alice and Stott, David J and Stricker, Bruno H and Stürmer, Til and Uitterlinden, André G and Wei, Wei-Qi and Westendorp, Rudi G J and Whitsel, Eric A and Wiggins, Kerri L and Wilke, Russell A and Ballantyne, Christie M and Colhoun, Helen M and Cupples, L Adrienne and Franco, Oscar H and Gudnason, Vilmundur and Hitman, Graham and Palmer, Colin N A and Psaty, Bruce M and Ridker, Paul M and Stafford, Jeanette M and Stein, Charles M and Tardif, Jean-Claude and Caulfield, Mark J and Jukema, J Wouter and Rotter, Jerome I and Krauss, Ronald M
Journal of Medical Genetics, ISSN 0022-2593, 12/2016, Volume 53, Issue 12, pp. 835 - 845
BackgroundIn addition to lowering low density lipoprotein cholesterol (LDL-C), statin therapy also raises high density lipoprotein cholesterol (HDL-C) levels.... 
LDL CHOLESTEROL | LOWERING RESPONSE | DENSITY-LIPOPROTEIN CHOLESTEROL | CORONARY ATHEROSCLEROSIS | CARDIOVASCULAR EVENTS | DISEASE | GENETICS & HEREDITY | RISK | TRANSFER PROTEIN GENE | ATORVASTATIN | LIPIDS | Index Medicus | HDL-Cholesterol | Pharmacogenetics | Genome-wide association study | Statins
Journal Article
Plos Genetics, ISSN 1553-7404, 2014, Volume 10, Issue 12, pp. e1004799 - e1004799
Journal Article
BMC Medical Genetics, ISSN 1471-2350, 10/2011, Volume 12, Issue 1, pp. 131 - 131
Background: The PHArmacogenetic study of Statins in the Elderly at risk (PHASE) is a genome wide association study in the PROspective Study of Pravastatin in... 
DENSITY-LIPOPROTEIN CHOLESTEROL | VARIANTS | LIPID-LEVELS | GENETICS & HEREDITY | RISK | LOCI | PRAVASTATIN | CORONARY-HEART-DISEASE | GENOME-WIDE ASSOCIATION | ARTERY-DISEASE | Blood circulation disorders | Low density lipoproteins | Physiological aspects | Genomes | Genetic aspects | Research | Risk factors | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, pp. e0149992 - e0149992
Journal Article
by Teumer, Alexander and Chaker, Layal and Groeneweg, Stefan and Li, Yong and Di Munno, Celia and Barbieri, Caterina and Schultheiss, Ulla T and Traglia, Michela and Ahluwalia, Tarunveer S and Akiyama, Masato and Appel, Emil Vincent R and Arking, Dan E and Arnold, Alice and Astrup, Arne and Beekman, Marian and Beilby, John P and Bekaert, Sofie and Boerwinkle, Eric and Brown, Suzanne J and De Buyzere, Marc and Campbell, Purdey J and Ceresini, Graziano and Cerqueira, Charlotte and Cucca, Francesco and Deary, Ian J and Deelen, Joris and Eckardt, Kai-Uwe and Ekici, Arif B and Eriksson, Johan G and Ferrrucci, Luigi and Fiers, Tom and Fiorillo, Edoardo and Ford, Ian and Fox, Caroline S and Fuchsberger, Christian and Galesloot, Tessel E and Gieger, Christian and Gögele, Martin and De Grandi, Alessandro and Grarup, Niels and Greiser, Karin Halina and Haljas, Kadri and Hansen, Torben and Harris, Sarah E and van Heemst, Diana and den Heijer, Martin and Hicks, Andrew A and den Hollander, Wouter and Homuth, Georg and Hui, Jennie and Ikram, M. Arfan and Ittermann, Till and Jensen, Richard A and Jing, Jiaojiao and Jukema, J. Wouter and Kajantie, Eero and Kamatani, Yoichiro and Kasbohm, Elisa and Kaufman, Jean-Marc and Kiemeney, Lambertus A and Kloppenburg, Margreet and Kronenberg, Florian and Kubo, Michiaki and Lahti, Jari and Lapauw, Bruno and Li, Shuo and Liewald, David C. M and Alizadeh, Behrooz Z and Boezen, H. Marike and Franke, Lude and van der Harst, Pim and Navis, Gerjan and Rots, Marianne and Snieder, Harold and Swertz, Morris A and Wijmenga, Cisca and Lim, Ee Mun and Linneberg, Allan and Marina, Michela and Mascalzoni, Deborah and Matsuda, Koichi and Medenwald, Daniel and Meisinger, Christa and Meulenbelt, Ingrid and De Meyer, Tim and Meyer zu Schwabedissen, Henriette E and Mikolajczyk, Rafael and Moed, Matthijs and Netea-Maier, Romana T and Nolte, Ilja M and Okada, Yukinori and Pala, Mauro and Pattaro, Cristian and Pedersen, Oluf and Petersmann, Astrid and Porcu, Eleonora and Postmus, Iris and Pramstaller, Peter P and Psaty, Bruce M and Ramos, Yolande F. M and ... and Lifelines Cohort Study
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4455 - 14
Journal Article