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Antioxidants & Redox Signaling, ISSN 1523-0864, 12/2016, Volume 25, Issue 17, pp. 921 - 935
Aims: Sickle retinopathy (SR) is a major cause of blindness in sickle cell disease (SCD). The genetic mutation responsible for SCD is known, however; oxidative... 
Original Research Communications | fetal hemoglobin induction | inflammation | Nrf2 | retina | monomethyl fumarate | oxidative stress | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROXYUREA | ELECTRORETINOGRAPHIC FINDINGS | PROTECTIVE ROLE | FETAL-HEMOGLOBIN | ENDOCRINOLOGY & METABOLISM | MICE | ANEMIA | ISCHEMIA-REPERFUSION | RETINAL-PIGMENT EPITHELIUM | Retina - drug effects | Retinal Pigment Epithelium - metabolism | Retina - metabolism | Humans | Neovascularization, Pathologic | Fumarates - administration & dosage | Retinal Diseases - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Retinal Pigment Epithelium - pathology | Retinal Diseases - etiology | gamma-Globulins - metabolism | Retinal Diseases - pathology | Retinal Neurons - drug effects | Nuclear Proteins - genetics | Disease Models, Animal | Retinal Pigment Epithelium - drug effects | Electroretinography | Gene Expression | Administration, Oral | Anemia, Sickle Cell - complications | Gene Expression Regulation | Nuclear Proteins - metabolism | Blood-Retinal Barrier - pathology | Blood-Retinal Barrier - metabolism | Carrier Proteins - genetics | Intercellular Adhesion Molecule-1 - metabolism | Animals | Carrier Proteins - metabolism | Retinal Neurons - metabolism | Intercellular Adhesion Molecule-1 - genetics | NF-E2-Related Factor 2 - metabolism | gamma-Globulins - genetics | Mice | Retinal Neurons - pathology | Anemia, Sickle Cell - blood | Anemia, Sickle Cell - diagnosis | Oxidative Stress - drug effects | Retinal Diseases - drug therapy | Retina - pathology | Antioxidants | Complications and side effects | Care and treatment | Sickle cell anemia | Retinal diseases | Health aspects | Risk factors | Oxidative stress | Animal models | Multiple sclerosis | Drug delivery systems | Retinopathy | Medical services | Innovations | Retina | Drug delivery | Proteins | Autopsy | Hemoglobin | Sickle cell disease | Formulations | Hematology | Complications | Fetuses | Abnormalities | Oral administration | Inflammation | Ribonucleic acid--RNA | Pathology | Fumaric acid | Blindness
Journal Article
EBioMedicine, ISSN 2352-3964, 09/2016, Volume 11, Issue C, pp. 138 - 150
Journal Article
Redox Biology, ISSN 2213-2317, 01/2020, Volume 28, p. 101336
The retinal pigment epithelium (RPE) is consistently exposed to high levels of pro-oxidant and inflammatory stimuli. As such, under normal conditions the... 
Oxidative stress | microRNA | Nrf2 | miR-144 | RPE | Retinal pigment epithelium
Journal Article
Oncotarget, 11/2017, Volume 8, Issue 61, p. 103568
Retinal neovascularization (RNV) is a sight threatening complication of ischemic retinopathies with limited therapeutic options. The transcription factor... 
Journal Article
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