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Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 4241 - 4241
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2018, Volume 20, Issue suppl_6, pp. vi98 - vi99
Abstract The purpose of this study is to improve the efficacy of imipridones, a novel class of AKT/ERK inhibitors. The lead compound ONC201 has entered... 
Abstracts
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2018, Volume 20, Issue suppl_6, pp. vi18 - vi19
Abstract BACKGROUND ONC201 selectively antagonizes DRD2, crosses the blood-brain barrier and induces apoptosis in high grade gliomas and other advanced... 
Abstracts
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3936 - 3936
Abstract Although standard induction therapy initially elicits a promising response in the majority of acute myeloid leukemia (AML) patients, the majority... 
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2018, Volume 20, Issue suppl_6, pp. vi90 - vi90
Abstract INTRODUCTION ONC201 is a highly selective antagonist of dopamine receptor D2 (DRD2) that is in phase II clinical trial as treatment for recurrent... 
Abstracts
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 202 - 202
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 12/2018
Dopamine receptor D2 (DRD2) is a G protein-coupled receptor antagonized by ONC201, an anti-cancer small molecule in clinical trials for high grade gliomas and... 
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 3732 - 3732
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2017, Volume 19, Issue suppl_6, pp. vi81 - vi82
ONC201, founding member of the imipridone class of compounds, has demonstrated evidence of tumor shrinkage along with exceptional safety in recurrent... 
Abstracts
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 5219 - 5219
Abstract ONC201 is a small molecule that is being developed as a novel anticancer drug based on its strong anti-tumor efficacy in preclinical models of... 
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2018, Volume 20, Issue suppl_6, pp. vi88 - vi88
Abstract Dopamine receptor D2 (DRD2) is a G protein-coupled receptor that is overexpressed in several cancers and its antagonism has been shown to cause... 
Abstracts
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 2497 - 2497
ONC201 is a first-in-class anti-tumor agent that selectively targets cancer cells without observed toxicity. ONC201 is being tested in phase III clinical... 
Journal Article
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