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The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 02/2018, Volume 141, Issue 2, pp. AB56 - AB56
Blood samples were drawn for assessment of C1-INH functional activity at screening; at weeks 1, 3, 5, 8, 11, and 14 of each treatment period; and at the... 
Teenagers | Pharmacology | Esterase | Angioedema | Age
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 2, pp. AB233 - AB233
  Methods Data from the COMPACT (Clinical Studies for Optimal Management in Preventing Angioedema with Low-Volume Subcutaneous C1-inhibitor Replacement... 
Allergy and Immunology | Allergy | Allergic reaction
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 2, pp. AB234 - AB234
  Assessments using the Treatment Satisfaction Questionnaire for Medication (TSQM), the Investigator's Global Assessment of Response to Therapy (IGART), and... 
Allergy and Immunology | Enzymes | Hydrolases
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 02/2019, Volume 143, Issue 2, pp. AB39 - AB39
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2017, Volume 376, Issue 12, pp. 1131 - 1140
Journal Article
PLOS ONE, ISSN 1932-6203, 01/2016, Volume 11, Issue 1, p. e0146783
Background and Purpose Ischemic stroke provokes severe brain damage and remains a predominant disease in industrialized countries. The coagulation factor XII... 
ISCHEMIA-REPERFUSION INJURY | STROKE | SYSTEM | ACTIVATION | THROMBUS FORMATION | MULTIDISCIPLINARY SCIENCES | MICE | PROVIDES PROTECTION | DEFICITS | CONTACT PATHWAY | INFESTIN-4 | Factor XIIa - metabolism | Cricetulus | Insect Proteins - pharmacology | Recombinant Fusion Proteins - pharmacology | Recombinant Fusion Proteins - therapeutic use | Rats | Male | Serum Albumin, Human | Brain - drug effects | Serine Proteinase Inhibitors - therapeutic use | Serum Albumin - therapeutic use | Brain - blood supply | Rotarod Performance Test | Animals | Factor XIIa - antagonists & inhibitors | Reperfusion Injury - prevention & control | Serum Albumin - pharmacology | Brain - pathology | Insect Proteins - therapeutic use | Infarction, Middle Cerebral Artery - drug therapy | Drug Evaluation, Preclinical | Serine Proteinase Inhibitors - pharmacology | CHO Cells | Complications and side effects | Care and treatment | Ischemia | Patient outcomes | Physiological aspects | Brain damage | Research | Blood coagulation factors | Drug therapy | Occlusion | Brain | Blood coagulation | Traumatic brain injury | Prophylaxis | Coagulation | Coagulation factor XIIa | Activation | Carotid arteries | Immunology | Reperfusion | Cerebral blood flow | Rodents | Physiology | Edema | Anticoagulants | Stroke | Inflammation | Survival | Thrombosis | Blood clots | Neurological diseases | Coagulation factors | Injury prevention | Brain research | Inhibitors | Brain injury | Coagulation factor XII | Veins & arteries
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2013, Volume 33, Issue 9, pp. 2202 - 2211
OBJECTIVE—The ability of high-density lipoprotein (HDL) to remove cholesterol from atherosclerotic plaque is thought to underlie its inverse correlation with... 
high-density lipoproteins, pre-ß | cholesterol | apolipoproteins | acute coronary syndrome | inflammation | REGRESSION | LECITHINCHOLESTEROL ACYLTRANSFERASE | CELLULAR CHOLESTEROL | HUMAN ATHEROSCLEROTIC PLAQUE | high-density lipoproteins, pre-beta | INTRAVENOUS-INFUSION | TRANSPORT | PERIPHERAL VASCULAR DISEASE | MICE | HEMATOLOGY | A-I | LECITHIN | Apolipoprotein A-I - pharmacology | Lipoproteins, HDL - pharmacokinetics | Up-Regulation | Anticholesteremic Agents - blood | Lipoproteins, HDL - blood | Cholesterol - blood | Humans | Cholesterol Esters - blood | Apolipoprotein A-I - pharmacokinetics | Lipoproteins, HDL - pharmacology | Biological Transport | Female | ATP Binding Cassette Transporter 1 | Macrophages - immunology | Cytokines - blood | Cell Line | Lipoproteins, HDL - administration & dosage | Rabbits | Anti-Inflammatory Agents - pharmacology | Inflammation Mediators - blood | Particle Size | Anticholesteremic Agents - pharmacokinetics | Macrophages - metabolism | Animals | ATP-Binding Cassette Transporters - drug effects | Anticholesteremic Agents - administration & dosage | ATP-Binding Cassette Transporters - blood | Cholesterol, HDL - blood | Macrophages - drug effects | Apolipoprotein A-I - administration & dosage | Mice | Infusions, Intravenous | Anticholesteremic Agents - pharmacology | Apolipoprotein A-I - blood
Journal Article
Critical Care Medicine, ISSN 0090-3493, 12/2016, Volume 44, Issue 12 Suppl 1, pp. 451 - 451
Journal Article
Critical Care Medicine, ISSN 0090-3493, 12/2016, Volume 44, Issue 12 Suppl 1, pp. 457 - 457
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 131, Issue 2, pp. AB109 - AB109
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 07/2015, Volume 113, Issue 4, pp. 870 - 880
Summary Factor VII (FVII) activating protease (FSAP) is a circulating protease with a putative function in blood coagulation and fibrinolysis. Genetic... 
Stroke, Systemic or Venous Thromboembolism | Haemostasis | Fibrinolysis | FSAP | Thrombosis | HABP2 | Coagulation | LIVER FIBROSIS | RISK | PROTEOLYSIS | fibrinolysis | thrombosis | haemostasis | G534E | PERIPHERAL VASCULAR DISEASE | MARBURG-I POLYMORPHISM | HEMATOLOGY | FACTOR PATHWAY INHIBITOR | Carotid Artery Diseases - prevention & control | Serine Endopeptidases - administration & dosage | Thrombosis - chemically induced | Carotid Artery Diseases - chemically induced | Mesenteric Vascular Occlusion - genetics | Venous Thromboembolism - blood | Chlorides | Serine Endopeptidases - genetics | Carotid Arteries - enzymology | Mesenteric Vascular Occlusion - enzymology | Thrombosis - blood | Thrombosis - prevention & control | Disease Models, Animal | Genetic Predisposition to Disease | Serine Endopeptidases - deficiency | Mesenteric Vascular Occlusion - prevention & control | Mice, Inbred C57BL | Thrombosis - enzymology | Hemostasis - genetics | Lipoproteins - blood | Mesenteric Vascular Occlusion - blood | Venous Thromboembolism - enzymology | Mice, Knockout | Ferric Compounds | Phenotype | Venous Thromboembolism - genetics | Animals | Carotid Artery Diseases - enzymology | Carotid Artery Diseases - blood | Collagen | Carotid Artery Diseases - genetics | Venous Thromboembolism - chemically induced | Blood Coagulation Tests | Thrombosis - genetics | Jugular Veins - enzymology | Norepinephrine | Mesenteric Vascular Occlusion - chemically induced | Mesenteric Arteries - enzymology
Journal Article
Journal Article
The Journal of Allergy and Clinical Immunology: In Practice, ISSN 2213-2198, 09/2018, Volume 6, Issue 5, pp. 1733 - 1741.e3
Hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE) impairs health-related quality of life (HRQoL). The objective of this study was to assess HRQoL... 
Productivity | Hereditary angioedema | Subcutaneous | HAEGARDA | Satisfaction | Patient-reported outcomes | C1-inhibitor protein | Quality of life | UNITED-STATES | DEPRESSION | MANAGEMENT | ANXIETY | ILLNESS | IMMUNOLOGY | C1 INHIBITOR | PROPHYLAXIS | HUMANISTIC BURDEN | ALLERGY | DISEASE | REPLACEMENT THERAPY | Angioedema | Prophylaxis | Data processing | FDA approval | Absenteeism | Mental depression | Patients | Studies | Disease prevention | Androgens | Anxieties | Anxiety
Journal Article