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Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 9074 - 14
Maf transcription factors are critical regulators of beta-cell function. We have previously shown that reduced MafA expression in human and mouse islets is... 
RHEUMATOID-ARTHRITIS | INSULIN | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | RISK | LOCI | DIFFERENTIATION | C-MAF | PANCREATIC LYMPH-NODES | T-CELLS | GENOME-WIDE ASSOCIATION | Transcription factors | CD8 antigen | Autoantigens | T cell receptors | Lymphocytes T | Inflammation | Gene expression | Lymph nodes | Thymus | CD4 antigen | Beta cells | T-cell receptor | Cell activation | B220 antigen | Lymphocytes B | Lymphocytes | Bone marrow | Pancreas
Journal Article
European Journal of Endocrinology, ISSN 0804-4643, 05/2017, Volume 176, Issue 5, pp. R247 - R267
Objective: To summarize the current knowledge on epigenetic alterations in mother and offspring subjected to gestational diabetes (GDM) and indicate future... 
Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
European Journal of Endocrinology, ISSN 0804-4643, 12/2018, Volume 179, Issue 6, pp. 363 - 372
Journal Article
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 09/2018, Volume 472, pp. 10 - 17
Journal Article
Genome Biology and Evolution, ISSN 1759-6653, 09/2018, Volume 10, Issue 10, p. 2697
It is often unavoidable to combine data from different sequencing centers or sequencing platforms when compiling datasets with a large number of individuals.... 
Genetik | Biological Sciences | Naturvetenskap | Genetics | Biologi | Natural Sciences | Bioinformatik och systembiologi | Bioinformatics and Systems Biology
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 38, pp. 13924 - 13929
Genetic variation can modulate gene expression, and thereby phenotypic variation and susceptibility to complex diseases such as type 2 diabetes (T2D). Here we... 
Beta cells | Databases | Allelic imbalance | Genes | Genetic loci | P values | Type 2 diabetes mellitus | Islets of Langerhans | Sequencing | Type 1 diabetes mellitus | PROVIDES INSIGHTS | VARIANTS | ALIGNMENT | RNA-SEQ | BETA-CELL TRANSCRIPTOME | MULTIDISCIPLINARY SCIENCES | INSULIN-SECRETION | GLYCEMIC TRAITS | DIABETES SUSCEPTIBILITY LOCI | EXPRESSION | ASSOCIATION | 5'-Nucleotidase - genetics | Cell Line | p21-Activated Kinases - genetics | Diabetes Mellitus, Type 2 - genetics | Genomics | Humans | Vesicular Transport Proteins - genetics | GPI-Linked Proteins - biosynthesis | Vesicular Transport Proteins - biosynthesis | Glucose - genetics | Male | RNA, Long Noncoding - genetics | Diabetes Mellitus, Type 2 - metabolism | Tetraspanins - biosynthesis | p21-Activated Kinases - biosynthesis | RNA, Long Noncoding - biosynthesis | Glucose - metabolism | Female | RNA Editing - physiology | Tetraspanins - genetics | Transcriptome - physiology | 5'-Nucleotidase - biosynthesis | GPI-Linked Proteins - genetics | Glucose metabolism | Pancreatic beta cells | Cell research | Genetic research | Genetic aspects | Genetic transcription | Research | Transcription factors | Pathogenesis | Glucose | Pancreas | Metabolism | Index Medicus | Biological Sciences | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
Islets, ISSN 1938-2014, 01/2019, Volume 11, Issue 1, pp. 10 - 20
Little is known about the expression and function of Retinoic acid-related orphan receptors (RORA, B, and C) in pancreatic β cells. Here in, we utilized cDNA... 
INS-1 (832/13) | Retinoic acid-related orphan receptor | gene expression microarray | Diabetes | insulin secretion | human islets | GAMMA-T | PANCREAS | ISOFORM | IDENTIFICATION | BETA | ORPHAN RECEPTOR-ALPHA | RETINOIC ACID | OSTEOBLASTS | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | TRANSCRIPTIONAL REGULATION
Journal Article
The Lancet Diabetes and Endocrinology, ISSN 2213-8587, 03/2018
Background: Diabetes is presently classified into two main forms, type 1 and type 2 diabetes, but type 2 diabetes in particular is highly heterogeneous. A... 
Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Endocrinology and Diabetes
Journal Article
The Lancet Diabetes & Endocrinology, ISSN 2213-8587, 05/2018, Volume 6, Issue 5, pp. 361 - 369
Journal Article
Biochemical and biophysical research communications, 11/2017
Osteopontin (OPN) is involved in various physiological processes and also implicated in multiple pathological states. It has been suggested that OPN may have a... 
Journal Article
by Gusarova, Viktoria and O'Dushlaine, Colm and Teslovich, Tanya M and Benotti, Peter N and Mirshahi, Tooraj and Gottesman, Omri and Van Hout, Cristopher V and Murray, Michael F and Mahajan, Anubha and Nielsen, Jonas B and Fritsche, Lars and Wulff, Anders Berg and Gudbjartsson, Daniel F and Sjögren, Marketa and Emdin, Connor A and Scott, Robert A and Lee, Wen-Jane and Small, Aeron and Kwee, Lydia C and Dwivedi, Om Prakash and Prasad, Rashmi B and Bruse, Shannon and Lopez, Alexander E and Penn, John and Marcketta, Anthony and Leader, Joseph B and Still, Christopher D and Kirchner, H. Lester and Mirshahi, Uyenlinh L and Wardeh, Amr H and Hartle, Cassandra M and Habegger, Lukas and Fetterolf, Samantha N and Tusie-Luna, Teresa and Morris, Andrew P and Holm, Hilma and Steinthorsdottir, Valgerdur and Sulem, Patrick and Thorsteinsdottir, Unnur and Rotter, Jerome I and Chuang, Lee-Ming and Damrauer, Scott and Birtwell, David and Brummett, Chad M and Khera, Amit V and Natarajan, Pradeep and Orho-Melander, Marju and Flannick, Jason and Lotta, Luca A and Willer, Cristen J and Holmen, Oddgeir L and Ritchie, Marylyn D and Ledbetter, David H and Murphy, Andrew J and Borecki, Ingrid B and Reid, Jeffrey G and Overton, John D and Hansson, Ola and Groop, Leif and Shah, Svati H and Kraus, William E and Rader, Daniel J and Chen, Yii-Der I and Hveem, Kristian and Wareham, Nicholas J and Kathiresan, Sekar and Melander, Olle and Stefansson, Kari and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and Abecasis, Goncalo R and Altshuler, David and Florez, Jose C and Boehnke, Michael and McCarthy, Mark I and Yancopoulos, George D and Carey, David J and Shuldiner, Alan R and Baras, Aris and Dewey, Frederick E and Gromada, Jesper and Diabetes - Cardiovascular Disease and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Diabetes - kardiovaskulär sjukdom and Lund University and Genomics, Diabetes and Endocrinology and EpiHealth: Epidemiology for Health and Genomik, diabetes och endokrinologi and Institutionen för kliniska vetenskaper, Malmö and Lunds universitet and Department of Clinical Sciences, Malmö
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2252 - 11
Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient... 
HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | MULTIDISCIPLINARY SCIENCES | MICE | ANGIOPOIETIN-LIKE PROTEIN-4 | LIPOPROTEIN-LIPASE | HAN CHINESE | CHINESE POPULATION | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | Diabetes Mellitus, Type 2 - genetics | Humans | Homeostasis | Male | Diabetes Mellitus, Type 2 - metabolism | Case-Control Studies | Genetic Variation | Diabetes Mellitus, Type 2 - etiology | Female | Lipoprotein Lipase - metabolism | Genetic Association Studies | Mice, Inbred C57BL | Risk Factors | Gene Silencing | Angiopoietin-like 4 Protein - deficiency | Mice, Knockout | Whole Exome Sequencing | Animals | Insulin Resistance - genetics | Angiopoietin-like 4 Protein - metabolism | Heterozygote | Mice | Blood Glucose - metabolism | Amino Acid Substitution | Angiopoietin-like 4 Protein - genetics | Deactivation | Angiopoietin | Diabetes mellitus | Health risks | Risk reduction | Risk | Lipoprotein lipase | Glucose | Lipase | Inactivation | Insulin | Proteins | Confidence intervals | Sensitivity | Nutrient loss | Rodents | Arteriosclerosis | Atherosclerosis | Genetics | Diabetes | Diabetes mellitus (non-insulin dependent) | Index Medicus | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Endocrinology and Diabetes
Journal Article
Journal Article