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Journal Article
Nucleic Acids Research, ISSN 0305-1048, 1/2008, Volume 36, Issue suppl_1, pp. D919 - D922
The molecular basis of drug action is often not well understood. This is partly because the very abundant and diverse information generated in the past decades... 
UNIPROT | PROTEIN DATA-BANK | DATABASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISCOVERY | Proteins - genetics | User-Computer Interface | Pharmaceutical Preparations - metabolism | Drug Design | Pharmaceutical Preparations - chemistry | Pharmacology | Internet | Proteins - chemistry | Databases, Factual | Drug Delivery Systems | Index Medicus
Journal Article
BMC Medicine, ISSN 1741-7015, 11/2010, Volume 8, Issue 1, pp. 70 - 70
Background: The incorporation of sex and gender-specific analysis in medical research is increasing due to pressure from public agencies, funding bodies, and... 
MORTALITY | TRIALS | MEDICINE, GENERAL & INTERNAL | DISEASE | ACUTE MYOCARDIAL-INFARCTION | RISK | WOMENS HEALTH | Publications - statistics & numerical data | Sex Distribution | Biomedical Research - trends | Female | Male | Humans | Evaluation | Usage | Animal models in research | Growth | Analysis | Sex differences (Psychology) | Science | Practice guidelines (Medicine) | Index Medicus
Journal Article
Science, ISSN 0036-8075, 12/2017, Volume 358, Issue 6367, p. eaan4368
Kinase inhibitors are important cancer therapeutics. Polypharmacology is commonly observed, requiring thorough target deconvolution to understand drug... 
REFINEMENT | PROTEIN | CHEMICAL PROTEOMICS | INHIBITOR SELECTIVITY | DATA QUALITY | QUANTIFICATION | MULTIDISCIPLINARY SCIENCES | INTEGRATIVE GENOMICS VIEWER | SALT-INDUCIBLE KINASES | CANCER | COMPREHENSIVE ANALYSIS | fms-Like Tyrosine Kinase 3 - antagonists & inhibitors | Lung Neoplasms - drug therapy | Lung Neoplasms - enzymology | Cytokines - metabolism | Humans | Drug Discovery - methods | Antineoplastic Agents - chemistry | Molecular Targeted Therapy | Xenograft Model Antitumor Assays | Leukemia, Myeloid, Acute - enzymology | Protein Kinase Inhibitors - chemistry | Animals | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Line, Tumor | Leukemia, Myeloid, Acute - drug therapy | Antineoplastic Agents - pharmacology | Mice | Protein Kinase Inhibitors - pharmacology | Proteomics - methods | Salts | Target recognition | Lung cancer | Selectivity | Drug development | Cancer therapies | Signal transduction | Biomolecules | Protein-tyrosine kinase | Tyrosine | Medical research | Imatinib | Decision making | Medical treatment | Mass spectroscopy | Tumor necrosis factor-α | Embryos | Bruton's tyrosine kinase | Mode of action | Side effects | Inhibitors | Interleukin 10 | Affinity | Drug discovery | Mass spectrometry | Acute myeloid leukemia | Drugs | Deregulation | Leukemia | Interleukin | Medical services | Clinical trials | Leucine | Kinases | Biological effects | Epidermal growth factor | Salt-inducible kinase | Xenografts | Cell survival | Epidermal growth factor receptors | Research & development--R&D | Therapeutic applications | Myeloid leukemia | Markers | Data processing | Lead compounds | Leucine zipper proteins | Signaling | Proteomics | Cancer | Index Medicus
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 7/2011, Volume 39, Issue suppl_2, pp. W215 - W222
The sheer volume of non-synonymous single nucleotide polymorphisms that have been generated in recent years from projects such as the Human Genome Project, the... 
POINT MUTATIONS | SUPPORT VECTOR MACHINES | MUTANTS | DATABASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SEQUENCE | DISEASE | RESIDUES | GENOME | AMINO-ACID SUBSTITUTION | TABLES | Proteins - genetics | Thermodynamics | Disease - genetics | Humans | Protein Conformation | Software | Internet | Mutation | Protein Stability | Amino Acid Substitution | Index Medicus
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2014, Volume 42, Issue 1, pp. D744 - D748
Scents are well known to be emitted from flowers and animals. In nature, these volatiles are responsible for inter- and intra-organismic communication, e. g.... 
WIDESPREAD | FUNGI | INDICATORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ORGANIC-COMPOUNDS | GROWTH | SOIL | DIVERSITY | ARABIDOPSIS | BACTERIAL VOLATILES | Bacteria - chemistry | Fungi - chemistry | Internet | Volatile Organic Compounds - chemistry | Databases, Chemical | Index Medicus | IV. Viruses, bacteria, protozoa and fungi
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, pp. e51020 - e51020
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 07/2014, Volume 42, Issue 1, pp. W53 - W58
Animal trials are currently the major method for determining the possible toxic effects of drug candidates and cosmetics. In silico prediction methods... 
DRUG | SUPERTARGET | FRAGMENTS | PHARMACOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPREHENSIVE DATABASE | SETS | CHEMISTRY | Animals | Administration, Oral | Computer Simulation | Pharmaceutical Preparations - chemistry | Rodentia | Rats | Software | Internet | Lethal Dose 50 | Toxicity Tests, Acute - methods | Index Medicus
Journal Article
Frontiers in chemistry, ISSN 2296-2646, 2018, Volume 6, pp. 93 - 93
Taste of a chemical compound present in food stimulates us to take in nutrients and avoid poisons. However, the perception of taste greatly depends on the... 
Models | Chemical senses | Chemical research | sweetness prediction | bitter prediction | KNIME workflow | taste prediction | Random Forest | fingerprints
Journal Article
Journal Article